Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jean Pierre Eliane"'
Autor:
Francesco Passamonti, Andrea Patriarca, Steven Knapper, Candido Rivera, Joseph M Scandura, Timothy Devos, Nikki Granacher, Adam Mead, Stephen Oh, Jeanne Palmer, Raajit K Rampal, Lino Teichmann, Qing LI, Jean-Pierre Eliane, Tzuu-Wang Chang, Sandra Klein, Gozde Colak, Claire Harrison
Publikováno v:
HemaSphere, Vol 7, p e9927843 (2023)
Externí odkaz:
https://doaj.org/article/7ddf83147e984511807a01aa1e288684
Autor:
Moshe Sade-Feldman, Yunxin J. Jiao, Jonathan H. Chen, Michael S. Rooney, Michal Barzily-Rokni, Jean-Pierre Eliane, Stacey L. Bjorgaard, Marc R. Hammond, Hans Vitzthum, Shauna M. Blackmon, Dennie T. Frederick, Mehlika Hazar-Rethinam, Brandon A. Nadres, Emily E. Van Seventer, Sachet A. Shukla, Keren Yizhak, John P. Ray, Daniel Rosebrock, Dimitri Livitz, Viktor Adalsteinsson, Gad Getz, Lyn M. Duncan, Bo Li, Ryan B. Corcoran, Donald P. Lawrence, Anat Stemmer-Rachamimov, Genevieve M. Boland, Dan A. Landau, Keith T. Flaherty, Ryan J. Sullivan, Nir Hacohen
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Resistance to immune-checkpoint blockade often occurs in treated patients. Here, the authors demonstrate that B2M loss is a mechanism of primary and acquired resistance to therapies targeting CTLA4 or PD-1 in melanoma patients.
Externí odkaz:
https://doaj.org/article/4b7fd694a84645dbafce545e168de8d2
Autor:
David A. Barbie, Cloud Peter Paweletz, David Dornan, Kwok-Kin Wong, Genevieve M. Boland, Roger D. Kamm, Keith T. Flaherty, F. Stephen Hodi, Patrick A. Ott, Jochen H. Lorch, Paul T. Kirschmeier, Gordon J. Freeman, Eliezer M. Van Allen, Levi A. Garraway, Meenhard Herlyn, Juan Miret, Charles H. Yoon, Raphael Bueno, William G. Richards, Joshua Wong, Vivek Sivathanu, Thanh U. Barbie, Benchun Miao, Rohit Thummalapalli, Shunsuke Kitajima, Brian C. Miller, James M. Cleary, Sareh Parangi, Viswanath Gunda, Guilherme Rabinowits, Nicole R. LeBoeuf, Manisha Thakuria, Benjamin Izar, Parin Shah, Mei-Ju Su, Lisa Cameron, Anat O. Stemmer-Rachamimov, Jean-Pierre Eliane, Adriano Piris, Mai P. Hoang, Wei Huang, Glenn J. Hanna, Shuai Li, Hua Zhang, Eric S. Wang, Raven Vlahos, Marc R. Hammond, Tran C. Thai, Israel Cañadas, Michal Barzily-Rokni, Zhiheng Jia, Lance Stapleton, Maria Anguiano, Lauren Keogh, Robert E. Jones, Asaf Rotem, Alicia Smart, Bart Phillips, Prafulla C. Gokhale, Andrew Portell, Joshua A. Kaplan, Chandrasekar Venkataramani, Max Quinn, Ashley Merlino, Jong Wook Kim, Hans Vitzthum, Mark Bittinger, Sangeetha Palakurthi, Zhi Wei, Chaoran Cheng, Tian Tian, Gao Zhang, William Walker, Meng Xiao He, Diana Miao, Hongye Liu, Jiehui Deng, Michaela Bowden, Chensheng W. Zhou, Susanna Stinson, Elena Ivanova, Patrick H. Lizotte, Amir R. Aref, Russell W. Jenkins
PDOTS Movie 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5816e3f89be3fcf42e03c4886a26bb
https://doi.org/10.1158/2159-8290.22531837.v1
https://doi.org/10.1158/2159-8290.22531837.v1
Autor:
David A. Barbie, Cloud Peter Paweletz, David Dornan, Kwok-Kin Wong, Genevieve M. Boland, Roger D. Kamm, Keith T. Flaherty, F. Stephen Hodi, Patrick A. Ott, Jochen H. Lorch, Paul T. Kirschmeier, Gordon J. Freeman, Eliezer M. Van Allen, Levi A. Garraway, Meenhard Herlyn, Juan Miret, Charles H. Yoon, Raphael Bueno, William G. Richards, Joshua Wong, Vivek Sivathanu, Thanh U. Barbie, Benchun Miao, Rohit Thummalapalli, Shunsuke Kitajima, Brian C. Miller, James M. Cleary, Sareh Parangi, Viswanath Gunda, Guilherme Rabinowits, Nicole R. LeBoeuf, Manisha Thakuria, Benjamin Izar, Parin Shah, Mei-Ju Su, Lisa Cameron, Anat O. Stemmer-Rachamimov, Jean-Pierre Eliane, Adriano Piris, Mai P. Hoang, Wei Huang, Glenn J. Hanna, Shuai Li, Hua Zhang, Eric S. Wang, Raven Vlahos, Marc R. Hammond, Tran C. Thai, Israel Cañadas, Michal Barzily-Rokni, Zhiheng Jia, Lance Stapleton, Maria Anguiano, Lauren Keogh, Robert E. Jones, Asaf Rotem, Alicia Smart, Bart Phillips, Prafulla C. Gokhale, Andrew Portell, Joshua A. Kaplan, Chandrasekar Venkataramani, Max Quinn, Ashley Merlino, Jong Wook Kim, Hans Vitzthum, Mark Bittinger, Sangeetha Palakurthi, Zhi Wei, Chaoran Cheng, Tian Tian, Gao Zhang, William Walker, Meng Xiao He, Diana Miao, Hongye Liu, Jiehui Deng, Michaela Bowden, Chensheng W. Zhou, Susanna Stinson, Elena Ivanova, Patrick H. Lizotte, Amir R. Aref, Russell W. Jenkins
In vitro kinase inhibitory activity of Compound 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aee36e2ca091d61ba8d57a8c6457e16a
https://doi.org/10.1158/2159-8290.22531825
https://doi.org/10.1158/2159-8290.22531825
Autor:
David A. Barbie, Cloud Peter Paweletz, David Dornan, Kwok-Kin Wong, Genevieve M. Boland, Roger D. Kamm, Keith T. Flaherty, F. Stephen Hodi, Patrick A. Ott, Jochen H. Lorch, Paul T. Kirschmeier, Gordon J. Freeman, Eliezer M. Van Allen, Levi A. Garraway, Meenhard Herlyn, Juan Miret, Charles H. Yoon, Raphael Bueno, William G. Richards, Joshua Wong, Vivek Sivathanu, Thanh U. Barbie, Benchun Miao, Rohit Thummalapalli, Shunsuke Kitajima, Brian C. Miller, James M. Cleary, Sareh Parangi, Viswanath Gunda, Guilherme Rabinowits, Nicole R. LeBoeuf, Manisha Thakuria, Benjamin Izar, Parin Shah, Mei-Ju Su, Lisa Cameron, Anat O. Stemmer-Rachamimov, Jean-Pierre Eliane, Adriano Piris, Mai P. Hoang, Wei Huang, Glenn J. Hanna, Shuai Li, Hua Zhang, Eric S. Wang, Raven Vlahos, Marc R. Hammond, Tran C. Thai, Israel Cañadas, Michal Barzily-Rokni, Zhiheng Jia, Lance Stapleton, Maria Anguiano, Lauren Keogh, Robert E. Jones, Asaf Rotem, Alicia Smart, Bart Phillips, Prafulla C. Gokhale, Andrew Portell, Joshua A. Kaplan, Chandrasekar Venkataramani, Max Quinn, Ashley Merlino, Jong Wook Kim, Hans Vitzthum, Mark Bittinger, Sangeetha Palakurthi, Zhi Wei, Chaoran Cheng, Tian Tian, Gao Zhang, William Walker, Meng Xiao He, Diana Miao, Hongye Liu, Jiehui Deng, Michaela Bowden, Chensheng W. Zhou, Susanna Stinson, Elena Ivanova, Patrick H. Lizotte, Amir R. Aref, Russell W. Jenkins
Device loading, media addition, media extraction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b6831b80aa77558ce1859b1d37bb61e
https://doi.org/10.1158/2159-8290.22531834.v1
https://doi.org/10.1158/2159-8290.22531834.v1
Autor:
Trevor J. Cunningham, Jean-Pierre Eliane, Kenneth H. Ngo, Milan J. Anadkat, Amir H. Ameri, Ilana S. Rosman, Amy Musiek, Maia Livneh, Sara Moradi Tuchayi, Thomas Horn, Anniek Zaalberg, Shadmehr Demehri
Publikováno v:
Journal of Investigative Dermatology. 139:62-70
High-risk skin cancer is a rare, but severe, complication associated with discoid lupus erythematosus (DLE). Chronic scar, inflammation, ultraviolet radiation and immunosuppressive medications are proposed explanations for this heightened skin cancer
Autor:
Mark A. Bittinger, Parin Shah, William F. Walker, Meng Xiao He, Nicole R. LeBoeuf, Chaoran Cheng, Rohit Thummalapalli, Chandrasekar Venkataramani, Glenn J. Hanna, Joshua A. Kaplan, Eliezer M. Van Allen, Jochen H. Lorch, Susanna Stinson, Raphael Bueno, Max M. Quinn, Michaela Bowden, Genevieve M. Boland, Cloud P. Paweletz, Bart Phillips, Gao Zhang, Jong Wook Kim, Adriano Piris, Patrick H. Lizotte, Raven Vlahos, Patrick A. Ott, Lance Stapleton, Levi A. Garraway, Hua Zhang, Chensheng W. Zhou, Jean Pierre Eliane, Eric S. Wang, Alicia Smart, Andrew Portell, Zhi Wei, Hongye Liu, Jiehui Deng, Meenhard Herlyn, Shuai Li, Diana Miao, Israel Cañadas, F. Stephen Hodi, Hans Vitzthum, Marc R. Hammond, Russell W. Jenkins, Prafulla C. Gokhale, Thanh U. Barbie, Michal Barzily-Rokni, David A. Barbie, Keith T. Flaherty, Tran C. Thai, Shunsuke Kitajima, Gordon J. Freeman, Roger D. Kamm, Juan J. Miret, Lauren Keogh, Elena Ivanova, Charles H. Yoon, Lisa A. Cameron, Viswanath Gunda, Ashley A. Merlino, David Dornan, Anat Stemmer-Rachamimov, Joshua A. Wong, Kwok-Kin Wong, William G. Richards, Sangeetha Palakurthi, Maria Anguiano, Wei Huang, Sareh Parangi, James M. Cleary, Benjamin Izar, Amir Reza Aref, Brian C. Miller, Vivek Sivathanu, Zhiheng Jia, Asaf Rotem, Mai P. Hoang, Paul Kirschmeier, Benchun Miao, Mei-Ju Su, Manisha Thakuria, Tian Tian, Robert E. Jones, Guilherme Rabinowits
Publikováno v:
Cancer Discovery. 8:196-215
Ex vivo systems that incorporate features of the tumor microenvironment and model the dynamic response to immune checkpoint blockade (ICB) may facilitate efforts in precision immuno-oncology and the development of effective combination therapies. Her
Autor:
Marina Kem, Meghan J. Mooradian, Justin F. Gainor, Tiffany Huynh, Mari Mino-Kenudson, Jean-Pierre Eliane, M. Lisa Zhang, A. John Iafrate
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 32(4)
Like programmed cell death ligand 1 (PD-L1), indoleamine 2,3-dioxygenase 1 (IDO1) is known to exert immunosuppressive effects and be variably expressed in human lung cancer. However, IDO1 expression has not been well studied in lung adenocarcinoma. P
Autor:
Cloud P. Paweletz, Vancheswaran Gopalakrishnan, Sangeetha M. Reddy, Stacey L. Bjorgaard, Elena Ivanova, Keren Yizhak, Gad Getz, Genevieve M. Boland, Alexandre Reuben, Nir Hacohen, Jennifer A. Wargo, David A. Barbie, Michal Barzily-Rokni, Shauna M. Blackmon, Jean Pierre Eliane, Russell W. Jenkins, John P. Ray, Andrew Portell, Patrick H. Lizotte, Jonathan H. Chen, Bo Li, Amir Reza Aref, David J. Lieb, Moshe Sade-Feldman, Carl G. de Boer, Alexandra-Chloé Villani, Hans Vitzthum, Dennie T. Frederick, Zachary A. Cooper, Paul Hoover, Samuel S. Freeman, Ryan J. Sullivan, Marc R. Hammond, Keith T. Flaherty, Anat Stemmer-Rachamimov
Publikováno v:
Cell. 175(4)
Treatment of cancer has been revolutionized by immune checkpoint blockade therapies. Despite the high rate of response in advanced melanoma, the majority of patients succumb to disease. To identify factors associated with success or failure of checkp
Autor:
Lyn M. Duncan, Mehlika Hazar-Rethinam, Yunxin J. Jiao, Jonathan H. Chen, Genevieve M. Boland, Jean Pierre Eliane, Dimitri Livitz, Marc R. Hammond, Keith T. Flaherty, Gad Getz, Moshe Sade-Feldman, Viktor A. Adalsteinsson, Brandon Nadres, Michael S. Rooney, Donald P. Lawrence, Keren Yizhak, Ryan J. Sullivan, Bo Li, Shauna M. Blackmon, Michal Barzily-Rokni, Dennie T. Frederick, John P. Ray, Nir Hacohen, Ryan B. Corcoran, Daniel Rosebrock, Emily E. Van Seventer, Sachet A. Shukla, Anat Stemmer-Rachamimov, Dan A. Landau, Hans Vitzthum, Stacey L. Bjorgaard
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Treatment with immune checkpoint blockade (CPB) therapies often leads to prolonged responses in patients with metastatic melanoma, but the common mechanisms of primary and acquired resistance to these agents remain incompletely characterized and have