Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jean Peluso"'
Autor:
Sarah Hassan, Jean Peluso, Sandra Chalhoub, Ysia Idoux Gillet, Nadia Benkirane-Jessel, Natacha Rochel, Guy Fuhrmann, Genevieve Ubeaud-Sequier
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0240676 (2020)
The impact of cancer on lifespan is significantly increasing worldwide. Enhanced activity of drug efflux pumps and the incidences of the tumor microenvironment such as the apparition of a hypoxic gradient inside of the bulk tumor, are the major cause
Externí odkaz:
https://doaj.org/article/d60be0a5429e464a83bf94e8905c6b2c
Autor:
Helena Moreira-Tabaka, Jean Peluso, Jean-Luc Vonesch, Didier Hentsch, Pascal Kessler, Jean-Marie Reimund, Serge Dumont, Christian D Muller
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e34184 (2012)
Tumor necrosis factor-alpha (TNF-α) is a pro-inflammatory cytokine today identified as a key mediator of several chronic inflammatory diseases. TNF-α, initially synthesized as a membrane-anchored precursor (pro-TNF-α), is processed by proteolytic
Externí odkaz:
https://doaj.org/article/f35f80021e1e40aa821afba47761124d
Autor:
Ferdinand Molnár, Rita Sigüeiro, Yoshiteru Sato, Clarisse Araujo, Inge Schuster, Pierre Antony, Jean Peluso, Christian Muller, Antonio Mouriño, Dino Moras, Natacha Rochel
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18124 (2011)
BackgroundThe 1α,25-dihydroxy-3-epi-vitamin-D3 (1α,25(OH)2-3-epi-D3), a natural metabolite of the seco-steroid vitamin D3, exerts its biological activity through binding to its cognate vitamin D nuclear receptor (VDR), a ligand dependent transcript
Externí odkaz:
https://doaj.org/article/25a28b670f684904a71dbf40fb88d15a
Autor:
Sandra Chalhoub, Guy Fuhrmann, Sarah Hassan, Natacha Rochel, Ysia Idoux Gillet, Genevieve Ubeaud-Sequier, Nadia Benkirane-Jessel, Jean Peluso
Publikováno v:
PLoS ONE
PLoS ONE, Public Library of Science, 2020, 15 (10), pp.e0240676. ⟨10.1371/journal.pone.0240676⟩
PLoS ONE, Vol 15, Iss 10, p e0240676 (2020)
PLoS ONE, 2020, 15 (10), pp.e0240676. ⟨10.1371/journal.pone.0240676⟩
PLoS ONE, Public Library of Science, 2020, 15 (10), pp.e0240676. ⟨10.1371/journal.pone.0240676⟩
PLoS ONE, Vol 15, Iss 10, p e0240676 (2020)
PLoS ONE, 2020, 15 (10), pp.e0240676. ⟨10.1371/journal.pone.0240676⟩
International audience; The impact of cancer on lifespan is significantly increasing worldwide. Enhanced activity of drug efflux pumps and the incidences of the tumor microenvironment such as the apparition of a hypoxic gradient inside of the bulk tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::801520679400f75950182fbcd072ff4e
https://hal.archives-ouvertes.fr/hal-03022804/document
https://hal.archives-ouvertes.fr/hal-03022804/document
Autor:
Laurence Kessler, Guillaume Kreutter, Ali El Habhab, Malak Abbas, Genevieve Ubeaud-Sequier, Mohamad Kassem, Lamia Amoura, Zobairi Fatiha, Julie Boisramé-Helms, Jean Peluso, Blandine Yver, Florence Toti, Philippe Baltzinger
Publikováno v:
Journal of Cellular and Molecular Medicine
Islet transplantation is associated with early ischaemia/reperfusion, localized coagulation and redox‐sensitive endothelial dysfunction. In animal models, islet cytoprotection by activated protein C (aPC) restores islet vascularization and protects
Publikováno v:
Cytometry Part A
Idiosyncratic drug-induced hepatotoxicity accounts for about 13% of all cases of acute liver failure, therefore cited as the most frequent reason for post-marketing drug withdrawal. Despite this, the underlying mechanisms remain poorly understood due
Autor:
Abdurazzag Abusnina, Tanveer Sharif, Guy Fuhrmann, Christian D. Muller, Jean Peluso, Mahmoud Alhosin, Claire Lugnier, Mayada Achour, Thierry Chataigneau, Valérie B. Schini-Kerth, Christian Bronner
Publikováno v:
Biochemical Pharmacology. 79:1251-1260
The salvage anti-tumoral pathway which implicates the p53-related p73 gene is not yet fully characterized. We therefore attempted to identify the up- and down-stream events involved in the activation of the p73-dependent pro-apoptotic pathway, by foc
Publikováno v:
Journal of Pharmacy and Pharmacology. 61:1473-1483
Objectives Flavonoids are phenolic compounds found in most edible fruits and vegetables. Previous studies have demonstrated their biological and beneficial effects on human health. However, their bioavailability and, in particular, their intestinal a
Autor:
Jean Peluso, Nathalie Taquet, Christian D. Muller, Helena Tabaka-Moreira, Jean-Marie Reimund, Dumont S
Publikováno v:
Cytometry Part A. :901-904
In parallel to gene therapy and cellular therapy it is clear that the more traditional pharmacological approaches still have a major role to play in the treatment of most diseases. Two drug-discovery strategies are widely used in the pharmaceutical i
Autor:
Genevieve Ubeaud-Sequier, Žiga Jakopin, Danijel Kikelj, Christian D. Muller, Janez Ilaš, Nace Zidar, Sanja Vrbek, Lucija Peterlin Mašič, Aleš Žula, Jean Peluso, Tihomir Tomašič, Marko Anderluh, Dominik Nabergoj, Marko Jukič, Marija Sollner Dolenc, Žiga Hodnik
Publikováno v:
MedChemComm
MedChemComm, Royal Society of Chemistry, 2015, 6 (1), pp.105-110. ⟨10.1039/c4md00286e⟩
MedChemComm, Royal Society of Chemistry, 2015, 6 (1), pp.105-110. ⟨10.1039/c4md00286e⟩
The marine alkaloids clathrodin, oroidin, and hymenidin, which were isolated from Agelas sponges, possess diverse biological activities. Herein, we describe the design of a library of their analogues and the evaluation of their apoptosis-inducing act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5844a81bbf82b10f12771329dec867c9
https://hal.archives-ouvertes.fr/hal-02106940
https://hal.archives-ouvertes.fr/hal-02106940