Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jean Paul ten Klooster"'
Autor:
Miriam J. Oost, Adil Ijaz, Daphne A. van Haarlem, Kitty van Summeren, Francisca C. Velkers, Aletta D. Kraneveld, Koen Venema, Christine A. Jansen, Raymond H. H. Pieters, Jean Paul ten Klooster
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Intestinal organoids are advanced cellular models, which are widely used in mammalian studies to mimic and study in vivo intestinal function and host–pathogen interactions. Growth factors WNT3 and RSPO1 are crucial for the growth of intest
Externí odkaz:
https://doaj.org/article/7b419c3d6b5942dcb11442a30baef2cf
Autor:
Jean Paul ten Klooster, Marianne Bol-Schoenmakers, Kitty van Summeren, Arno L. W. van Vliet, Cornelis A. M. de Haan, Frank J. M. van Kuppeveld, Saertje Verkoeijen, Raymond Pieters
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
ten Klooster et al. use ileum-derived organoids and report that bacterial and viral stimuli can drive IL22 production by T cells via distinct signaling pathways, and that IL22 can stimulate expression of anti-microbial and antiviral factors. This stu
Externí odkaz:
https://doaj.org/article/60c64a2589874380b2adeb1328a5a8e9
Autor:
Joyce Aarts, Annemarie Boleij, Bartijn C. H. Pieters, Anouk L. Feitsma, R. J. Joost van Neerven, Jean Paul ten Klooster, Laura M’Rabet, Onno J. Arntz, Marije I. Koenders, Fons A. J. van de Loo
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Many studies provided compelling evidence that extracellular vesicles (EVs) are involved in the regulation of the immune response, acting as both enhancers and dampeners of the immune system, depending on the source and type of vesicle. Research, inc
Externí odkaz:
https://doaj.org/article/7206aa4f590f40579215db13f8663deb
Autor:
Andrijana Nešić, Annemarie Stam, Milena Čavić, Jean Paul Ten Klooster, Raymond Pieters, Joost Smit, Marija Gavrović-Jankulović
Publikováno v:
Journal of Functional Foods, Vol 62, Iss , Pp - (2019)
In this study, two intestinal models were employed to assess the modulatory potential of a major kiwifruit allergen on the innate immunity of epithelial cells. Effects of Act d 1 were analyzed in terms of gene expression and structural changes of tig
Externí odkaz:
https://doaj.org/article/410787c3bbe94e02a85dcdb6bc4fd611
Autor:
Anouk L. Feitsma, Fons A. J. van de Loo, Jean Paul ten Klooster, Laura M’Rabet, Annemarie Boleij, Marije I. Koenders, R. J. Joost van Neerven, Onno J. Arntz, Bartijn C. H. Pieters, Joyce Aarts
Publikováno v:
Frontiers in Immunology, 12
Frontiers in Immunology
Frontiers in Immunology 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
Many studies provided compelling evidence that extracellular vesicles (EVs) are involved in the regulation of the immune response, acting as both enhancers and dampeners of the immune system, depending on the source and type of vesicle. Research, inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0224e3b9fb615489d7125c73055d486f
Autor:
Kitty van Summeren, Melanie Hesse, Jordy J.M. Bomers, Carin Biel, Peter Olinga, Jean Paul ten Klooster, Stefan Vaessen, Marc Teunis, Emilia Bigaeva
Publikováno v:
Toxicology in Vitro, 69:104974. PERGAMON-ELSEVIER SCIENCE LTD
Precision-cut intestinal slices (PCIS) are used to study intestinal (patho)physiology, drug efficacy, toxicity, transport and metabolism ex vivo. One of the factors that limit the use of PCIS is a relatively short life-span. Moreover, culture-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22dec791a97660f053545579c3e212cd
https://doi.org/10.1016/j.tiv.2020.104974
https://doi.org/10.1016/j.tiv.2020.104974
Autor:
Harry Gruppen, Jean-Paul Vincken, Jocelijn Meijerink, Renger F. Witkamp, Jean Paul ten Klooster, Michiel G.J. Balvers, Renate L. M. Jansen, Ya Wang, Pierluigi Plastina
Publikováno v:
ACS Chemical Neuroscience, 8(3), 548-557. ACS publications
ACS Chemical Neuroscience 8 (2017) 3
ACS Chemical Neuroscience, 8(3), 548-557
ACS Chemical Neuroscience 8 (2017) 3
ACS Chemical Neuroscience, 8(3), 548-557
Several studies indicate that the n-3 long-chain polyunsaturated fatty acid docosahexaenoic acid (DHA) contributes to an attenuated inflammatory status in the development of neurodegenerative disorders, such as Alzheimer's and Parkinson's disease. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f42b6553b8945ec3a64c351394e0690
https://surfsharekit.nl/public/82e0473a-e2ce-477a-b482-0ce6e0f8a388
https://surfsharekit.nl/public/82e0473a-e2ce-477a-b482-0ce6e0f8a388
Autor:
Nicolai E. Savaskan, Willem-Jan Keune, Peter L. Hordijk, Francis van Horck, Iman van den Bout, Jean Paul ten Klooster, Amra Hajdo-Milasinovic, Mireille Snell, Nullin Divecha, Jonathan R. Halstead
Publikováno v:
Journal of cell science, 123(20), 3535-3546. Company of Biologists Ltd
Halstead, J R, Savaskan, N E, Van Den Bout, I, Van Horck, F, Hajdo-Milasinovic, A, Snell, M, Keune, W J, Ten Klooster, J P, Hordijk, P L & Divecha, N 2010, ' Rac controls PIP5K localisation and PtdIns(4,5)P2 synthesis, which modulates vinculin localisation and neurite dynamics ', Journal of Cell Science, vol. 123, no. 20, pp. 3535-3546 . https://doi.org/10.1242/jcs.062679
Journal of Cell Science, 123(20), 3535-3546. Company of Biologists Ltd
Halstead, J R, Savaskan, N E, Van Den Bout, I, Van Horck, F, Hajdo-Milasinovic, A, Snell, M, Keune, W J, Ten Klooster, J P, Hordijk, P L & Divecha, N 2010, ' Rac controls PIP5K localisation and PtdIns(4,5)P2 synthesis, which modulates vinculin localisation and neurite dynamics ', Journal of Cell Science, vol. 123, no. 20, pp. 3535-3546 . https://doi.org/10.1242/jcs.062679
Journal of Cell Science, 123(20), 3535-3546. Company of Biologists Ltd
In N1E-115 cells, neurite retraction induced by neurite remodelling factors such as lysophosphatidic acid, sphingosine 1-phosphate and semaphorin 3A require the activity of phosphatidylinositol 4-phosphate 5-kinases (PIP5Ks). PIP5Ks synthesise the ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8050ab98d6103aa79278180c9554352
https://doi.org/10.1242/jcs.062679
https://doi.org/10.1242/jcs.062679
Publikováno v:
Physiological Reviews, 89(3), 777-798. American Physiological Society
Jansen M, ten Klooster JP, Offerhaus GJ, Clevers H. LKB1 and AMPK Family Signaling: The Intimate Link Between Cell Polarity and Energy Metabolism. Physiol Rev 89: 777-798, 2009; doi:10.1152/physrev.00026.2008. Research on the LKB1 tumor suppressor pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ea72cf822726c56e1ffba9d7f0c5fcd
https://doi.org/10.1152/physrev.00026.2008
https://doi.org/10.1152/physrev.00026.2008
Autor:
Frédéric Colland, Jin Yuan, Peter Hornbeck, Marnix Jansen, Jean Paul ten Klooster, John de Koning, Harry Begthel, Viola Oorschot, Hans Clevers, Valeria Di Giacomo, Madelon M. Maurice
Publikováno v:
Developmental Cell, 16(4), 551-562. Cell Press
SummaryThe human Lkb1 kinase, encoded by the ortholog of the invertebrate Par4 polarity gene, is mutated in Peutz-Jeghers cancer syndrome. Lkb1 activity requires complex formation with the pseudokinase Strad and the adaptor protein Mo25. The complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2be824b3f74b6e8be841e419a86506d8
https://doi.org/10.1016/j.devcel.2009.01.016
https://doi.org/10.1016/j.devcel.2009.01.016