Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Jean P. Thiery"'
Autor:
Gro V. Røsland, Sissel E. Dyrstad, Deusdedit Tusubira, Reham Helwa, Tuan Zea Tan, Maria L. Lotsberg, Ina K. N. Pettersen, Anna Berg, Charlotte Kindt, Fredrik Hoel, Kirstine Jacobsen, Ari J. Arason, Agnete S. T. Engelsen, Henrik J. Ditzel, Per E. Lønning, Camilla Krakstad, Jean P. Thiery, James B. Lorens, Stian Knappskog, Karl J. Tronstad
Publikováno v:
Cancer & Metabolism, Vol 7, Iss 1, Pp 1-18 (2019)
Abstract Background Epithelial to mesenchymal transition (EMT) is a well-characterized process of cell plasticity that may involve metabolic rewiring. In cancer, EMT is associated with malignant progression, tumor heterogeneity, and therapy resistanc
Externí odkaz:
https://doaj.org/article/34446e854aaf4dda922810b5f57564ec
Autor:
Debasish Boral, Monika Vishnoi, Haowen N. Liu, Wei Yin, Marc L. Sprouse, Antonio Scamardo, David S. Hong, Tuan Z. Tan, Jean P. Thiery, Jenny C. Chang, Dario Marchetti
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Characterization of CTCs derived from breast cancer patients with brain metastasis (BCBM) may allow for early diagnosis of brain metastasis and/or help for treatment choice and its efficacy. In this study, the authors identify a unique signature, bas
Externí odkaz:
https://doaj.org/article/924c0ac03d9d404c931127a48b58fb79
Autor:
Jing-Yu Wang, Xiao-Ping Zhang, Hong-Kun Zhou, Hong-Xin Cai, Jin-Biao Xu, Bao-Gang Xie, Jean-Paul Thiery, Wu Zhou
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract RNA interactomes and their diversified functionalities have recently benefited from critical methodological advances leading to a paradigm shift from a conventional conception on the regulatory roles of RNA in pathogenesis. However, the dyna
Externí odkaz:
https://doaj.org/article/aaf2b5f259cc4c7ab235a25c338a8aeb
Autor:
Xianning Lai, Sarah Kit Leng Lui, Hiu Yan Lam, Yuta Adachi, Wen Jing Sim, Natali Vasilevski, Nicola J. Armstrong, Stephanie Claire Bridgeman, Nathan Michael Main, Tuan Zea Tan, Janina E. E. Tirnitz-Parker, Jean Paul Thiery, Hiromichi Ebi, Alan Prem Kumar, Pieter Johan Adam Eichhorn
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-14 (2023)
Abstract Despite the promising antitumor activity of SHP2 inhibitors in RAS-dependent tumours, overall responses have been limited by their narrow therapeutic window. Like with all MAPK pathway inhibitors, this is likely the result of compensatory pa
Externí odkaz:
https://doaj.org/article/375510663f6147c1abe8dec01b58fcb1
Autor:
Jin Biao Xu, Jun Cao, Jin Xia, Ying Zhu, Yi He, Ming Guo Cao, Bing Mu Fang, Jean Paul Thiery, Wu Zhou
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-21 (2023)
Abstract Metastasis accounts for most cancer-associated deaths; yet, this complex process remains poorly understood, particularly the relationship between distant metastasis and primary site-derived cells. Here, we modified the classical MMTV–PyMT
Externí odkaz:
https://doaj.org/article/91c4ea1aed774660b5c858ce54a8b1f3
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/cafa766a9bf34c739b1c96d4555bfaee
Autor:
Yuanbin Cui, Tingjie Yuan, Ying Wang, Diwei Zheng, Le Qin, Shanglin Li, Zhiwu Jiang, Shouheng Lin, Wenjing Guo, Zhi Wang, Zhaoduan Liang, Yi Li, Yao Yao, Xingguo Liu, Qiannan Tang, Hai-Yan Tu, Xu-Chao Zhang, Zhaoyang Tang, Nathalie Wong, Zhenfeng Zhang, Dajiang Qin, Jean Paul Thiery, Kailin Xu, Peng Li
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112797- (2023)
Summary: Chimeric antigen receptor (CAR) T cell therapy lacks persistent efficacy with “on-target, off-tumor” toxicities for treating solid tumors. Thus, an antibody-guided switchable CAR vector, the chimeric Fc receptor CD64 (CFR64), composed of
Externí odkaz:
https://doaj.org/article/19026a5a9b9f441696fdcf97f3be7fbe
Autor:
Zhao Liu, Chen Zhang, Beiming Cui, Yijie Wang, Kaisheng Lim, Kai Li, Jean Paul Thiery, Jun Chen, Chun Loong Ho
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 161, Iss , Pp 114443- (2023)
Protein-based cancer therapies are considered an alternative to conventional anticancer regimens, providing multifunctional properties while showing low toxicity. However, its widespread use is limited by absorption and instability issues, resulting
Externí odkaz:
https://doaj.org/article/b75b0cb998ea4f6682456896be71e62d
Autor:
Meriem Hasmim, Malina Xiao, Kris Van Moer, Akinchan Kumar, Alexandra Oniga, Michel Mittelbronn, Caroline Duhem, Anwar Chammout, Guy Berchem, Jean Paul Thiery, Marianna Volpert, Brett Hollier, Muhammad Zaeem Noman, Bassam Janji
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Triple-negative subtype of breast cancer (TNBC) is hallmarked by frequent disease relapse and shows highest mortality rate. Although PD-1/PD-L1 immune checkpoint blockades have recently shown promising clinical benefits, the overall response rate rem
Externí odkaz:
https://doaj.org/article/35d1f9ea5edc46af8039bc9506e5c176
Publikováno v:
Clinical and Translational Discovery, Vol 2, Iss 1, Pp n/a-n/a (2022)
Abstract Gene expression profiling is commonly used to define molecular subtypes in cancers and gene sets can be identified as prognostic indicators or as potential biomarkers. Reverse transcription‐quantitative real‐time polymerase chain reactio
Externí odkaz:
https://doaj.org/article/1ea15466644c43f084943fb7145138f2