Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Jean P. Thiery"'
Autor:
Jing-Yu Wang, Xiao-Ping Zhang, Hong-Kun Zhou, Hong-Xin Cai, Jin-Biao Xu, Bao-Gang Xie, Jean-Paul Thiery, Wu Zhou
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract RNA interactomes and their diversified functionalities have recently benefited from critical methodological advances leading to a paradigm shift from a conventional conception on the regulatory roles of RNA in pathogenesis. However, the dyna
Externí odkaz:
https://doaj.org/article/aaf2b5f259cc4c7ab235a25c338a8aeb
Autor:
Xianning Lai, Sarah Kit Leng Lui, Hiu Yan Lam, Yuta Adachi, Wen Jing Sim, Natali Vasilevski, Nicola J. Armstrong, Stephanie Claire Bridgeman, Nathan Michael Main, Tuan Zea Tan, Janina E. E. Tirnitz-Parker, Jean Paul Thiery, Hiromichi Ebi, Alan Prem Kumar, Pieter Johan Adam Eichhorn
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-14 (2023)
Abstract Despite the promising antitumor activity of SHP2 inhibitors in RAS-dependent tumours, overall responses have been limited by their narrow therapeutic window. Like with all MAPK pathway inhibitors, this is likely the result of compensatory pa
Externí odkaz:
https://doaj.org/article/375510663f6147c1abe8dec01b58fcb1
Autor:
Jin Biao Xu, Jun Cao, Jin Xia, Ying Zhu, Yi He, Ming Guo Cao, Bing Mu Fang, Jean Paul Thiery, Wu Zhou
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-21 (2023)
Abstract Metastasis accounts for most cancer-associated deaths; yet, this complex process remains poorly understood, particularly the relationship between distant metastasis and primary site-derived cells. Here, we modified the classical MMTV–PyMT
Externí odkaz:
https://doaj.org/article/91c4ea1aed774660b5c858ce54a8b1f3
Akademický článek
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Akademický článek
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Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/cafa766a9bf34c739b1c96d4555bfaee
Akademický článek
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Autor:
Le Qin, Yuanbin Cui, Tingjie Yuan, Dongmei Chen, Ruocong Zhao, Shanglin Li, Zhiwu Jiang, Qiting Wu, Youguo Long, Suna Wang, Zhaoyang Tang, Huixia Pan, Xiaoping Li, Wei Wei, Jie Yang, Xuequn Luo, Zhenfeng Zhang, Qiannan Tang, Pentao Liu, Robert Weinkove, Yao Yao, Dajiang Qin, Jean Paul Thiery, Peng Li
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Co-expression of PD-L1-specific chimeric switch receptors (CSRs) improves the antitumor effects of chimeric antigen receptor (CAR) T cells. Here, CSRs are shown to promote the differentiation of mesothelin-targeting CAR T cells into central memory-li
Externí odkaz:
https://doaj.org/article/d2342c54a2474b7a9866f95bebd32b0a
Autor:
Yuanbin Cui, Tingjie Yuan, Ying Wang, Diwei Zheng, Le Qin, Shanglin Li, Zhiwu Jiang, Shouheng Lin, Wenjing Guo, Zhi Wang, Zhaoduan Liang, Yi Li, Yao Yao, Xingguo Liu, Qiannan Tang, Hai-Yan Tu, Xu-Chao Zhang, Zhaoyang Tang, Nathalie Wong, Zhenfeng Zhang, Dajiang Qin, Jean Paul Thiery, Kailin Xu, Peng Li
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112797- (2023)
Summary: Chimeric antigen receptor (CAR) T cell therapy lacks persistent efficacy with “on-target, off-tumor” toxicities for treating solid tumors. Thus, an antibody-guided switchable CAR vector, the chimeric Fc receptor CD64 (CFR64), composed of
Externí odkaz:
https://doaj.org/article/19026a5a9b9f441696fdcf97f3be7fbe
Autor:
Jean Agnetti, Vanessa Bou Malham, Christophe Desterke, Nassima Benzoubir, Juan Peng, Sophie Jacques, Souad Rahmouni, Emanuel Di Valentin, Tuan Zea Tan, Didier Samuel, Jean Paul Thiery, Ama Gassama-Diagne
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Overexpression of isoform δ of phosphoinositide 3-kinase (PI3Kδ) promotes stemness in hepatocellular carcinoma cell lines and mouse liver, whereas its inhibition promotes EMT, suggesting a key role for PI3Kδ in epithelial plasticity.
Externí odkaz:
https://doaj.org/article/b4d2124ccf174f3b8ca36dab0e6b9aba