Výsledky vyhledávání - "Jean P. Lariviere"

Tissue pO2 of Orthotopic 9L and C6 Gliomas and Tumor-Specific Response to Radiotherapy and Hyperoxygenation

Autor: Harold M. Swartz, Huagang Hou, Eugene Demidenko, David J. Gladstone, Nadeem Khan, Jean P. Lariviere, Hongbin Li

Publikováno v: International Journal of Radiation Oncology*Biology*Physics. 73:878-885

Purpose Tumor hypoxia is a well-known therapeutic problem; however, a lack of methods for repeated measurements of glioma partial pressure of oxygen (pO 2 ) limits the ability to optimize the therapeutic approaches. We report the effects of 9.3 Gy of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3884825f89c4a14794bc725f02c09bbf
https://doi.org/10.1016/j.ijrobp.2008.10.025

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Arsenic as an Endocrine Disruptor: Arsenic Disrupts Retinoic Acid Receptor–and Thyroid Hormone Receptor–Mediated Gene Regulation and Thyroid Hormone–Mediated Amphibian Tail Metamorphosis

Autor: Jennifer C. Davey, Cavus Batki, Athena P. Nomikos, Manida Wungjiranirun, Jenna R. Sherman, Liam Ingram, Joshua W. Hamilton, Jean P. Lariviere

Publikováno v: Environmental Health Perspectives

Exposure to excess arsenic, principally from contaminated drinking water, is considered one of the top environmental health threats both in the United States and worldwide [Abernathy et al. 2003; Mukherjee et al. 2006; National Research Council (NRC)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdedecfb76eab7a4cf0aad8a63fc7400
https://doi.org/10.1289/ehp.10131

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Skeletal Muscle and Glioma Oxygenation by Carbogen Inhalation in Rats: A Longitudinal Study by EPR Oximetry Using Single-Probe Implantable Oxygen Sensors

Autor: Benjamin B. Williams, Jean P. Lariviere, Harold M. Swartz, Periannan Kuppusamy, Sassan Hodge, Eunice Y. Chen, Huagang Hou, Nadeem Khan, Alan Eastman, Lesley A. Jarvis

Publikováno v: Advances in Experimental Medicine and Biology ISBN: 9781493905836

The feasibility of EPR oximetry using a single-probe implantable oxygen sensor (ImOS) was tested for repeated measurement of pO₂ in skeletal muscle and ectopic 9L tumors in rats. The ImOS (50 mm length) were constructed using nickel-chromium alloy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2b1140b21b40f2de339db9c6058ef13
https://europepmc.org/articles/PMC4301407/

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Arsenic alters the function of the glucocorticoid receptor as a transcription factor

Autor: Alisa M. Davis, Jean P. Lariviere, Joshua W. Hamilton, Ronald C. Kaltreider

Publikováno v: Environmental Health Perspectives

Chronic human exposure to nonovertly toxic doses of arsenic is associated with an increased risk of cancer. Although its carcinogenic mechanism is still unknown, arsenic does not directly cause DNA damage or mutations and is therefore thought to act

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd2445127d6102b8c7a9c70b82a6ba0
http://europepmc.org/articles/PMC1240242

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Differential effects of arsenic(III) and chromium(VI) on nuclear transcription factor binding

Autor: Michael A. Ihnat, Jean P. Lariviere, Ronald C. Kaltreider, Joshua W. Hamilton, Carrie A. Pesce

Publikováno v: Molecular Carcinogenesis. 25:219-229

The toxic metals arsenic(III) and chromium(VI) are considered human carcinogens, although they may act through different mechanisms. We previously showed that when administered at single low, non-overtly toxic doses, chromium, arsenic, and several ot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::08f852e1d91ee7bd6cbe77d6b7e04b33
https://doi.org/10.1002/(sici)1098-2744(199907)25:3<219::aid-mc8>3.0.co

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Dynamic changes in oxygenation of intracranial tumor and contralateral brain during tumor growth and carbogen breathing: a multisite EPR oximetry with implantable resonators

Autor: Harold M. Swartz, Ruhong Dong, Benjamin B. Williams, Jean P. Lariviere, Hongbin Li, Risto A. Kauppinen, Shahryar K. Hekmatyar, Huagang Hou, Nadeem Khan

Publikováno v: Journal of magnetic resonance (San Diego, Calif. : 1997). 214(1)

Several techniques currently exist for measuring tissue oxygen; however technical difficulties have limited their usefulness and general application. We report a recently developed electron paramagnetic resonance (EPR) oximetry approach with multiple

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b59b765ab5533695ef6c363cba8424
https://pubmed.ncbi.nlm.nih.gov/22033225

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Repeated tumor oximetry to identify therapeutic window during metronomic cyclophosphamide treatment of 9L gliomas

Autor: Harold M. Swartz, Nadeem Khan, Youssef Jounaidi, Huagang Hou, Sriram P. Mupparaju, Jean P. Lariviere

Publikováno v: Oncology reports. 26(1)

Malignant gliomas are aggressive and angiogenic tumors with high VEGF content. Consequently, approaches such as metronomic chemotherapy, which have an anti-angiogenic effect, are being investigated. However, a lack of an appropriate technique that ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9184f37e379b76826e1f0f1bf0d8c148
https://pubmed.ncbi.nlm.nih.gov/21503586

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Synergistic combination of hyperoxygenation and radiotherapy by repeated assessments of tumor pO2 with EPR oximetry

Autor: Huagang Hou, Jean P. Lariviere, Nadeem Khan, Ruhong Dong, Harold M. Swartz, Sriram P. Mupparaju

Carbogen/EPR oximetry/Irradiation/Tumor oxygenation. The effect of hyperoxygenation with carbogen (95% O2 + 5% CO2) inhalation on RIF-1 tumor pO2 and its consequence on growth inhibition with fractionated radiotherapy is reported. The temporal change

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39f1c9d1747a4bef61efd512e126a486
https://europepmc.org/articles/PMC3955714/

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Modulation of Tumor Hypoxia by Topical Formulations with Vasodilators for Enhancing Therapy

Autor: Nadeem Khan, Harold M. Swartz, Kristl Julijana, Jean P. Lariviere, Zrinka Abramović, Marjeta Šentjurc, Huagang Hou

Publikováno v: Oxygen Transport to Tissue XXXII ISBN: 9781441977557

Tumor hypoxia is a well known therapeutic problem which contributes to radioresistance and aggressive tumor characteristics. Lack of techniques for repeated measurements of tumor oxygenation (pO(2), partial pressure of oxygen) has restricted the opti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e73575a53d5e30a8db2373fa1e420a98
https://doi.org/10.1007/978-1-4419-7756-4_11

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