Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jean Osterman"'
Autor:
Wenhui Zhou, Vinayaka Kotraiah, Jean Osterman, Joshua J. Kimball, Poncho Meisenheimer, Jolanta Vidugiriene, James J. Cali, Michael P. Valley, Laurent Bernad, Sarah Duellman
Publikováno v:
Analytical biochemistry. 434(2)
The aldehyde dehydrogenase (ALDH) family of enzymes is critical for cell survival and adaptation to cellular and environmental stress. These enzymes are of interest as therapeutic targets and as biomarkers of stem cells. This article describes a nove
Autor:
James J. Cali, Carolyn C. Woodroofe, Dieter Klaubert, Jean Osterman, William J. Daily, Poncho Meisenheimer, Monika G. Wood, John Shultz
Publikováno v:
Biochemistry. 47(39)
A set of 6'-alkylated aminoluciferins are shown to be bioluminescent substrates for Ultra-Glo and QuantiLum luciferases. These studies demonstrate that both the engineered and wild-type firefly luciferases tolerate much greater steric bulk at the 6'
Autor:
Jolanta Vidugiriene, Wenhui Zhou, Laurent Bernad, Poncho Meisenheimer, Ruslan Arbit, Sarah Duellman, Jean Osterman, James J. Cali
Publikováno v:
Cancer Research. 74:3743-3743
Cell-based assay development for cancer drug discovery continues to advance toward more innovative methods that provide efficient workflow and meaningful data. Rapid, sensitive techniques that are non-lytic and therefore facilitate multiplexing with
Autor:
Sarah Duellman, Jean Osterman, Jolanta Vidugiriene, Dieter Klaubert, John Shultz, Poncho Meisenheimer, Wenhui Zhou, Hui Wang, Donna Leippe, James J. Cali, Mary Sobol
Publikováno v:
Cancer Research. 72:1135-1135
Cancer is a disease defined by uncontrolled cell growth where cellular energy metabolism pathways must evolve for tumors to survive and proliferate. NAD(P) and NAD(P)H play a major role in oxidative phosphorylation and their role in aerobic glycolysi