Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jean Mehdi Jouniaux"'
Autor:
Jean-Yves Scoazec, Francois-Xavier Danlos, Laurence Albiges, Bernard Escudier, Ronan Flippot, Lydie Cassard, Nathalie Chaput, Natacha Naoun, Marie Naigeon, Jean-Mehdi Jouniaux, Lisa Boselli, Lucia Carril-Ajuria, Marcus Teixeira, Macarena Rey-Cardenas, Larissa Rainho
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Immunotherapy profoundly changed the landscape of cancer therapy by providing long-lasting responses in subsets of patients and is now the standard of care in several solid tumor types. However, immunotherapy activity beyond conventional immune check
Externí odkaz:
https://doaj.org/article/4d45ec442ac34e56a8ca723b8b181cf8
Autor:
Jean-Yves Scoazec, Antoine Hollebecque, Aurélien Marabelle, Alexandra Leary, Lydie Cassard, Nathalie Chaput, Cristina Smolenschi, Perrine Vuagnat, Jean-Mehdi Jouniaux, Laetitia Nebot-Bral, Andrey A Yurchenko, Louise de Forceville, Mathieu Danjou, Reginaldo C A Rosa, Caroline Pouvelle, Said Aoufouchi, Emeline Colomba, Sergey Nikolaev, Patricia Kannouche
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 7 (2022)
Background Clinical studies have highlighted the efficacy of anti-programmed death 1 (αPD-1) monoclonal antibodies in patients with DNA mismatch repair-deficient (MMRD) tumors. However, the responsiveness of MMRD cancers to αPD-1 therapy is highly
Externí odkaz:
https://doaj.org/article/e34026e4687a48cba574cb8fd575cd1c
Autor:
Francois-Xavier Danlos, Aurélien Marabelle, Roberto Ferrara, Benjamin Besse, Lydie Cassard, Nathalie Chaput, Aude Desnoyer, Boris Duchemann, Marie Naigeon, Edouard Auclin, Jean-Mehdi Jouniaux, Lisa Boselli, Jonathan Grivel, Laura Mezquita, Caroline Caramella
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)
Externí odkaz:
https://doaj.org/article/0b1156acb9124f3095fba919615b8ea0
Autor:
Clélia Coutzac, Jean-Mehdi Jouniaux, Angelo Paci, Julien Schmidt, Domenico Mallardo, Atmane Seck, Vahe Asvatourian, Lydie Cassard, Patrick Saulnier, Ludovic Lacroix, Paul-Louis Woerther, Aurore Vozy, Marie Naigeon, Laetitia Nebot-Bral, Mélanie Desbois, Ester Simeone, Christine Mateus, Lisa Boselli, Jonathan Grivel, Emilie Soularue, Patricia Lepage, Franck Carbonnel, Paolo Antonio Ascierto, Caroline Robert, Nathalie Chaput
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
The gut microbiota has been reported to regulate the efficacy of cancer therapy. Here, the authors show that short-chain fatty acids, which are generated through bacterial fermentation, increases immune tolerance leading to resistance to anti-CTLA-4
Externí odkaz:
https://doaj.org/article/1117fcdf2fd44e30b8bbaa1e829d3ecf
Autor:
Nathalie Chaput, Benjamin Besse, Siham Farhane, Anne-Laure Voisin, Aurelien Marabelle, Jean-Charles Soria, Marina C. Garassino, Claudia Proto, Sabina Sangaletti, Jordi Remon, David Planchard, Lizza Hendriks, Caroline Caramella, Matthieu Texier, Laura Mezquita, Aude Desnoyer, Jonathan Grivel, Lisa Boselli, Jean-Mehdi Jouniaux, Lydie Cassard, Boris Duchemann, Edouard Auclin, Marie Naigeon, Roberto Ferrara
Variation of SIP in the overall ICI cohort and in progressing and non-progressing patients (A). Variation of immunosenescence markers (CD28 absence, CD57 expression, KLRG1 expression) on CD4 and CD8+ T-cells and variation of circulating TEMRA, naïve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bada29424b1782cef0aa346a18fd88cc
https://doi.org/10.1158/1078-0432.22479165.v1
https://doi.org/10.1158/1078-0432.22479165.v1
Autor:
Nathalie Chaput, Benjamin Besse, Siham Farhane, Anne-Laure Voisin, Aurelien Marabelle, Jean-Charles Soria, Marina C. Garassino, Claudia Proto, Sabina Sangaletti, Jordi Remon, David Planchard, Lizza Hendriks, Caroline Caramella, Matthieu Texier, Laura Mezquita, Aude Desnoyer, Jonathan Grivel, Lisa Boselli, Jean-Mehdi Jouniaux, Lydie Cassard, Boris Duchemann, Edouard Auclin, Marie Naigeon, Roberto Ferrara
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f645cacbf655cdfd4d672dc95fb9b34
https://doi.org/10.1158/1078-0432.22479138.v1
https://doi.org/10.1158/1078-0432.22479138.v1
Autor:
Nathalie Chaput, Benjamin Besse, Siham Farhane, Anne-Laure Voisin, Aurelien Marabelle, Jean-Charles Soria, Marina C. Garassino, Claudia Proto, Sabina Sangaletti, Jordi Remon, David Planchard, Lizza Hendriks, Caroline Caramella, Matthieu Texier, Laura Mezquita, Aude Desnoyer, Jonathan Grivel, Lisa Boselli, Jean-Mehdi Jouniaux, Lydie Cassard, Boris Duchemann, Edouard Auclin, Marie Naigeon, Roberto Ferrara
Patients characteristics in ICI discovery and validation cohorts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb2e88f63de0a82db5138d21a126d2b
https://doi.org/10.1158/1078-0432.22479132
https://doi.org/10.1158/1078-0432.22479132
Autor:
Nathalie Chaput, Benjamin Besse, Siham Farhane, Anne-Laure Voisin, Aurelien Marabelle, Jean-Charles Soria, Marina C. Garassino, Claudia Proto, Sabina Sangaletti, Jordi Remon, David Planchard, Lizza Hendriks, Caroline Caramella, Matthieu Texier, Laura Mezquita, Aude Desnoyer, Jonathan Grivel, Lisa Boselli, Jean-Mehdi Jouniaux, Lydie Cassard, Boris Duchemann, Edouard Auclin, Marie Naigeon, Roberto Ferrara
Purpose:CD28, CD57, and KLRG1 have been previously identified as markers of T-cell immunosenescence. The impact of immunosenescence on anti-PD(L)-1 (ICI) or platinum-based chemotherapy (PCT) in patients with advanced non–small cell lung cancer (aNS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574bae3f5dfa72155755473b5d9513e8
https://doi.org/10.1158/1078-0432.c.6530142.v1
https://doi.org/10.1158/1078-0432.c.6530142.v1
Autor:
Lydie Cassard, Claudia Proto, Caroline Caramella, Boris Duchemann, Jean-Charles Soria, Siham Farhane, Jean Mehdi Jouniaux, Sabina Sangaletti, Nathalie Chaput, L. Boselli, Roberto Ferrara, Anne-Laure Voisin, Aude Desnoyer, Jordi Remon, M. Naigeon, Marina Chiara Garassino, Edouard Auclin, Laura Mezquita, Jonathan Grivel, Benjamin Besse, Lizza E.L. Hendriks, M. Texier, David Planchard, Aurélien Marabelle
Publikováno v:
Clinical Cancer Research, 27(2), 492-503. American Association for Cancer Research Inc.
Purpose: CD28, CD57, and KLRG1 have been previously identified as markers of T-cell immunosenescence. The impact of immunosenescence on anti-PD(L)-1 (ICI) or platinum-based chemotherapy (PCT) in patients with advanced non–small cell lung cancer (aN
Autor:
Boris Duchemann, Marie Naigeon, Edouard Auclin, Roberto Ferrara, Lydie Cassard, Jean-Mehdi Jouniaux, Lisa Boselli, Jonathan Grivel, Aude Desnoyer, François-Xavier Danlos, Laura Mezquita, Caroline Caramella, Aurelien Marabelle, Benjamin Besse, Nathalie Chaput
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)
BackgroundProgrammed cell death protein-1 (PD-1) expression has been associated with activation and exhaustion of both the CD4 and CD8 populations in advanced non-small cell lung cancer (aNSCLC). Nevertheless, the impact of the balance between circul