Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Jean Marie Gillardin"'
Gastroprotective Effect of Saccharomyces boulardii in a Rat Model of Ibuprofen-Induced Gastric Ulcer
Publikováno v:
Pharmacology. 85:188-193
Background/Aims: Saccharomyces boulardii is a probiotic yeast which has been shown to protect the gastrointestinal microflora from disequilibrium and from associated gastrointestinal disorders. However, no study has explored the potential effect of t
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 36:655-661
1. The aim of the present study was to test the hypothesis that increasing GABAergic neurotransmission is involved in the prevention or treatment of brain oedema. The study was conducted in the well-established rat triethyltin (TET) model of brain oe
Publikováno v:
Alcohol. 43:197-206
Change in the function of gamma-aminobutyric acid(A) (GABA(A)) receptors attributable to alterations in receptor subunit composition is one of main molecular mechanisms with those affecting the glutamatergic system which accompany prolonged alcohol (
Publikováno v:
Pharmacology. 83:243-246
Background/Aims: Post-operative nausea and vomiting are common adverse events that require administration of anti-emetic compounds, such as the serotonin 5-HT3 receptor antagonists, but these drugs can also reduce the analgesic efficacy of some analg
Autor:
Yann Le Fur, Jean-Marie Gillardin, Marc Verleye, David Bendahan, Marie‐Emmanuelle Le Guern, Marguerite Izquierdo, Benoît Giannesini, Patrick J. Cozzone
Publikováno v:
European Journal of Pharmacology
European Journal of Pharmacology, Elsevier, 2009, 602 (1), pp.143-7
European Journal of Pharmacology, 2009, 602 (1), pp.143-7
European Journal of Pharmacology, Elsevier, 2009, 602 (1), pp.143-7
European Journal of Pharmacology, 2009, 602 (1), pp.143-7
Although citrulline malate (CM; CAS 54940-97-5, Stimol) is used against fatigue states, its anti-asthenic effect remains poorly documented. The objective of this double-blind study was to evaluate the effect of oral ingestion of CM on a rat model of
Publikováno v:
Psychopharmacology. 197:523-534
A disordered regulation of neuroactive steroids release in response to acute stress could induce GABAergic dysfunctions underlying anxiety disorders.First, we conducted studies indicating that a short immobilization stress in anxious Balb/cByJ mice p
Autor:
Marc Verleye, Benoît Giannesini, Marguerite Izquierdo, Patrick J. Cozzone, Christiane Dalmasso, Jean-Marie Gillardin, Marie‐Emmanuelle Le Guern, Yann Le Fur, David Bendahan
Publikováno v:
Muscle & Nerve. 37:496-504
Although depletion in high-energy phosphorylated compounds and mitochondrial impairment have been reported in septic skeletal muscle at rest, their impact on energy metabolism has not been documented during exercise. In this study we aimed to investi
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 85:556-561
The potent antidepressant effect of moclobemide, a selective and reversible type A monoamine oxidase (MAO) inhibitor, is clinically established. In view of the ongoing debate on the neuroprotective properties of MAO inhibitors, the present study was
Publikováno v:
Brain Research. 1138:30-38
Recent data suggested the existence of a bidirectional relation between depression and neurodegenerative diseases resulting from cerebral ischemia injury. Glutamate, a major excitatory neurotransmitter, has long been recognised to play a key role in
Autor:
Jean-Marie Gillardin, Philippe Girard, Yannick Pansart, Danielle Verniers, Marie-Claude Coppé
Publikováno v:
Pharmacological Research. 54:195-202
The non-opiate analgesic nefopam has been shown to inhibit monoamines uptake, but little is known about receptor subtypes effectively involved in its analgesic effect. In vitro binding assays yielded the following measures of affinity (IC(50)): serot