Orthoparamyxovirinae C Proteins Have a Common Origin and a Common Structural Organization

Autor: Ada Roy, Emeric Chan Mine, Lorenzo Gaifas, Cédric Leyrat, Valentina A. Volchkova, Florence Baudin, Luis Martinez-Gil, Viktor E. Volchkov, David G. Karlin, Jean-Marie Bourhis, Marc Jamin

Publikováno v: Biomolecules, Vol 13, Iss 3, p 455 (2023)

The protein C is a small viral protein encoded in an overlapping frame of the P gene in the subfamily Orthoparamyxovirinae. This protein, expressed by alternative translation initiation, is a virulence factor that regulates viral transcription, repli

Externí odkaz: https://doaj.org/article/6b1b455b2d7547619ee63737e9669b89

Borna Disease Virus 1 Phosphoprotein Forms a Tetramer and Interacts with Host Factors Involved in DNA Double-Strand Break Repair and mRNA Processing

Autor: Nicolas Tarbouriech, Florian Chenavier, Junna Kawasaki, Kamel Bachiri, Jean-Marie Bourhis, Pierre Legrand, Lily L. Freslon, Estelle M. N. Laurent, Elsa Suberbielle, Rob W. H. Ruigrok, Keizo Tomonaga, Daniel Gonzalez-Dunia, Masayuki Horie, Etienne Coyaud, Thibaut Crépin

Publikováno v: Viruses, Vol 14, Iss 11, p 2358 (2022)

Determining the structural organisation of viral replication complexes and unravelling the impact of infection on cellular homeostasis represent important challenges in virology. This may prove particularly useful when confronted with viruses that po

Externí odkaz: https://doaj.org/article/34e8c32a029f431cb149b615aea698bd

Structural Dynamics of the C-terminal X Domain of Nipah and Hendra Viruses Controls the Attachment to the C-terminal Tail of the Nucleocapsid Protein

Autor: Jean-Marie Bourhis, Filip Yabukarski, Guillaume Communie, Robert Schneider, Valentina A. Volchkova, Mickaël Frénéat, Francine C. Gérard, Corinne Ducournau, Caroline Mas, Nicolas Tarbouriech, Malene Ringkjøbing Jensen, Viktor E. Volchkov, Martin Blackledge, Marc Jamin

Publikováno v: Journal of Molecular Biology
Journal of Molecular Biology, 2022, 434 (10), pp.167551. ⟨10.1016/j.jmb.2022.167551⟩

International audience; To understand the dynamic interactions between the phosphoprotein (P) and the nucleoprotein (N) within the transcription/replication complex of the $Paramyxoviridae$ and to decipher their roles in regulating viral multiplicati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deec8a0b5e039148bbb6bb0ac3086267
https://pubmed.ncbi.nlm.nih.gov/35317998

Structural Description of the Nipah Virus Phosphoprotein and Its Interaction with STAT1

Autor: Valentina A. Volchkova, Caroline Mas, Malene Ringkjøbing Jensen, Eric Condamine, Martin Blackledge, Jean-Marie Bourhis, Guillaume Communie, Marc Jamin, Nicolas Tarbouriech, Filip Yabukarski, Viktor E. Volchkov

Publikováno v: Biophysical Journal
Biophysical Journal, 2020, 118 (10), pp.2470-2488. ⟨10.1016/j.bpj.2020.04.010⟩
Biophysical Journal, Biophysical Society, 2020, 118 (10), pp.2470-2488. ⟨10.1016/j.bpj.2020.04.010⟩
Biophys J

International audience; The structural characterization of modular proteins containing long intrinsically disordered regions intercalated with folded domains is complicated by their conformational diversity and flexibility and requires the integratio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::551c128bb7d5233e21ab4a2ac9ddf441
https://hal.science/hal-02867772/file/S0006349520303283.pdf

Cytosolic 5'-triphosphate ended viral leader transcript of measles virus as activator of the RIG I-mediated interferon response.

Autor: Sébastien Plumet, Florence Herschke, Jean-Marie Bourhis, Hélène Valentin, Sonia Longhi, Denis Gerlier

Publikováno v: PLoS ONE, Vol 2, Iss 3, p e279 (2007)

BACKGROUND: Double stranded RNA (dsRNA) is widely accepted as an RNA motif recognized as a danger signal by the cellular sentries. However, the biology of non-segmented negative strand RNA viruses, or Mononegavirales, is hardly compatible with the pr

Externí odkaz: https://doaj.org/article/36e996ccc72a4d619cd4dbbf212795c7