Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Jean Marie Besson"'
Publikováno v:
Anesthesiology. 104:1257-1265
Background Pain during labor is a common and severe phenomenon, but its clinical management remains haphazard because its neurophysiology is poorly understood. In the current study, the authors evaluate the parturient rat as a relevant model to study
Publikováno v:
European Journal of Pharmacology. 514:121-130
We studied the effects of the high-efficacy 5-hydroxytryptamine1A (5-HT1A) receptor agonist, F 13640 on both formalin-induced spinal cord c-Fos protein expression and pain behaviours in the rat. Replicating earlier data, F 13640 (0.63 mg/kg, i.p.; t(
Autor:
Jean-Marie Besson, Marie-Claude Fournie-Zaluski, Jaroslava Buritova, Stéphanie Le Guen, Bernard P. Roques
Publikováno v:
European Journal of Pain. 7:241-249
The effects of the S enantiomer of RB101, a complete inhibitor of enkephalin-catabolizing enzymes, alone or in combination with a functional NMDA receptor antagonist, (+)-HA966 were studied on the spinal c-Fos protein expression in the carrageenan mo
Publikováno v:
European Journal of Neuroscience. 17:2425-2437
We have recently shown concurrent changes in behavioural responses and c-Fos protein expression in the central nervous system in both naive and morphine-dependent rats after systemic administration of the opioid antagonist naloxone. However, because
Autor:
Jaroslava Buritova, Stéphanie Le Guen, Gwénaëlle Catheline, Jean Marie Besson, Marie Claude Fournie-Zaluski, Bernard P. Roques
Publikováno v:
Brain Research. 967:106-112
We have previously shown that RB101, a dual inhibitor of enkephalin-degrading enzymes, decreased carrageenin-evoked c-Fos protein expression at the spinal cord level in awake rats. Moreover, we have also shown that c-Fos expression is a useful marker
Autor:
Jean-Marie Besson, Jaroslava Buritova
Publikováno v:
Brain Research. 891:281-284
Urethane anaesthesia strongly reduced the peripheral edema (31+/-5 and 96+/-8% reduction of carrageenan-enhanced paw and ankle diameters, respectively; P
Publikováno v:
The Journal of Comparative Neurology. 427:285-301
This study examined the possibility that a tonic activity in the endogenous opioid systems (EO systems) exists in animals under normal conditions. In a first set of experiments, concurrent changes in behavioral responses and in the numbers of c-Fos-l
Autor:
Patrick W. Mantyh, Prisca Honore, Scott D. Rogers, Patrick M. Menning, Michael L. Nichols, Allan I. Basbaum, Jean Marie Besson
Publikováno v:
The Journal of Neuroscience. 19:7670-7678
Inflammatory pain involves the sensitization of both primary afferent and spinal cord neurons. To explore the neurochemical changes that contribute to inflammatory pain, we have examined the expression and ligand-induced internalization of the substa
Publikováno v:
European Journal of Pharmacology. 373:1-11
This study investigated the contribution of NMDA receptors to the development of tolerance to the antinociceptive properties of morphine at the level of the spinal cord dorsal horn. The expression of c-Fos protein following intraplantar (i.pl.) injec
Publikováno v:
European Journal of Pharmacology. 370:287-296
In an attempt to study the anti-inflammatory and the antinociceptive effects of a kappa1-opioid receptor agonist (U-69,593: trans-3,4-dichloro-N-methyl-N-[7-(1-pyrrolidinyl)cycloexil]benzene acetamide methanesulfonate), we used a combination of the m