Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Jean Marc Steyaert"'
Autor:
Jorgelindo da Veiga Moreira, Minoo Hamraz, Mohammad Abolhassani, Erwan Bigan, Sabine Pérès, Loïc Paulevé, Marcel Levy Nogueira, Jean-Marc Steyaert, Laurent Schwartz
Publikováno v:
Metabolites, Vol 6, Iss 4, p 33 (2016)
To better understand the energetic status of proliferating cells, we have measured the intracellular pH (pHi) and concentrations of key metabolites, such as adenosine triphosphate (ATP), nicotinamide adenine dinucleotide (NAD), and nicotinamide adeni
Externí odkaz:
https://doaj.org/article/93d7ac790bad421f883c8ef670c569d5
Publikováno v:
Journal of computational biology : a journal of computational molecular cell biology. 27(3)
Autor:
Bruno Dubois, Erwan Bigan, Olivier Lafitte, Laurent Schwartz, Mohammad Abolhassani, Jean-Marc Steyaert, Minoo Hamraz, Marcel Levy Nogueira
Publikováno v:
Alzheimer's & Dementia. 14:444-453
Introduction Exposure to traumatic brain injury is a core risk factor that predisposes an individual to sporadic neurodegenerative diseases. We provide evidence that mechanical stress increases brain levels of hallmark proteins associated with neurod
Autor:
Thierry Meinnel, Carmela Giglione, Willy V. Bienvenut, Coralie L Ebert, Cyril Dian, Sarah Ciccone, Benoit Castrec, Jean-Marc Steyaert, Jean-Pierre Le Caer
Publikováno v:
Nature Chemical Biology
Nature Chemical Biology, Nature Publishing Group, 2018, 14, pp.671-679. ⟨10.1038/s41589-018-0077-5⟩
Nature Chemical Biology, 2018, 14, pp.671-679. ⟨10.1038/s41589-018-0077-5⟩
Nature Chemical Biology, Nature Publishing Group, 2018, 14, pp.671-679. ⟨10.1038/s41589-018-0077-5⟩
Nature Chemical Biology, 2018, 14, pp.671-679. ⟨10.1038/s41589-018-0077-5⟩
International audience; An organism’s entire protein modification repertoire has yet to be comprehensively mapped. N-myristoylation (MYR) is a crucial eukaryotic N-terminal protein modification. Here we mapped complete Homo sapiens and Arabidopsis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b5c53e0a717959e04fb1417bcd642d7
https://hal-cea.archives-ouvertes.fr/cea-01873857
https://hal-cea.archives-ouvertes.fr/cea-01873857
Publikováno v:
Drug Resistance Updates
Drug Resistance Updates, Elsevier, 2018, 38, pp.1-11. ⟨10.1016/j.drup.2018.03.001⟩
Drug Resistance Updates, 2018, 38, pp.1-11. ⟨10.1016/j.drup.2018.03.001⟩
Drug Resistance Updates, Elsevier, 2018, 38, pp.1-11. ⟨10.1016/j.drup.2018.03.001⟩
Drug Resistance Updates, 2018, 38, pp.1-11. ⟨10.1016/j.drup.2018.03.001⟩
International audience; Cancer cells employ both conventional oxidative metabolism and glycolytic anaerobic metabolism. However, their proliferation is marked by a shift towards increasing glycolytic metabolism even in the presence of O2 (Warburg eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e00087acda3df7dbb0d700d6b42b8be1
https://www.hal.inserm.fr/inserm-02096107
https://www.hal.inserm.fr/inserm-02096107
The growing number of RNA-mediated regulation mechanisms identified in the last decades suggests a widespread impact of RNA-RNA interactions. The efficiency of the regulation relies on highly specific and coordinated interactions, while simultaneousl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::231fcf7b771d42e25e34a33b67f08f3c
Publikováno v:
Alzheimer's & Dementia. 12:324-333
Introduction Extracellular accumulation of amyloid-β protein and intracellular accumulation of tau in brain tissues have been described in animal models of Alzheimer's disease (AD) and mechanical stress-based diseases of different mechanisms, such a
Publikováno v:
Origins of Life and Evolution of Biospheres. 45:439-454
Osmotic pressure arising from a higher total chemical concentration inside proto-cells is thought to have played a role in the emergence and selection of self-replicating proto-cells. We present two chemical schemes through which different equilibriu
Publikováno v:
Artificial Life
Artificial Life, Massachusetts Institute of Technology Press (MIT Press), 2014, 21 (2), pp.166-92
Artificial Life, 2014, 21 (2), pp.166-92
Artificial Life, Massachusetts Institute of Technology Press (MIT Press), 2014, 21 (2), pp.166-92
Artificial Life, 2014, 21 (2), pp.166-92
International audience; We show that self-replication of a chemical system encapsulated within a membrane growing from within is possible without any explicit feature such as autocatalysis or metabolic closure, and without the need for their emergenc
Autor:
Laurent Schwartz, Perrine Kafara, Jean-Marc Steyaert, Philippe Icard, Hubert Lincet, T. Vallantin
Publikováno v:
Oncologie. 17:315-320
Les tumeurs cancereuses se comportent comme des parasites metaboliques qui puisent dans les reserves de l’hote pour alimenter leurs biosyntheses, tandis qu’elles secretent des dechets (NO, polyamines, ammoniac, lactate…) qui favorisent la crois