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pro vyhledávání: '"Jean Maguire van Seventer"'
Infectious disease control and prevention relies on a thorough understanding of the factors determining transmission. This article summarizes the fundamental principles of infectious disease transmission while highlighting many of the agent, host, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::519358a4966004220c73f9ca7255a1c3
https://doi.org/10.1016/b978-0-12-803678-5.00516-6
https://doi.org/10.1016/b978-0-12-803678-5.00516-6
Publikováno v:
Annales Nestlé (Ed. española). 67:105-121
Una interacción compleja entre factores ambientales y humanos, incluyendo factores ecológicos, genéticos, políticos y socioeconómicos, es responsable de la emergencia y la resurgencia de enfermedades infecciosas. Estos factores poseen a menudo u
Publikováno v:
Annales Nestlé (Ed. française). 67:105-121
L’interaction complexe de facteurs humains et environnementaux (facteurs écologiques, génétiques, politiques et socioéconomiques) est responsable de l’émergence et la réémergence de maladies infectieuses. Ces facteurs ont souvent un effet
Publikováno v:
Annales Nestlé (English ed.). 67:103-118
A complex interplay of environmental and human factors, including ecological, genetic, political and socioeconomic factors, is responsible for the emergence and re-emergence of infectious diseases. These factors often have a distinct effect on childr
Autor:
Jean Maguire van Seventer, John A. Meyers, Calvin F. Roff, Alyson J. Mangini, David Sehy, Taro Nagai, Gijs A. van Seventer
Publikováno v:
Cytokine. 35:235-246
Type I interferons (IFN) (IFN-alpha/beta) are recognized as both inhibitors and effectors of autoimmune disease. In multiple sclerosis, IFN-beta therapy appears beneficial, in part, due to its suppression of autoimmune inflammatory Th cell responses.
Autor:
David L. Perkins, Gijs A. van Seventer, Thomas F. Mueller, Odile Devergne, Taro Nagai, Jean Maguire van Seventer
Publikováno v:
The Journal of Immunology. 171:5233-5243
Type I IFNs, IFN-α and IFN-β, are early effectors of innate immune responses against microbes that can also regulate subsequent adaptive immunity by promoting antimicrobial Th1-type responses. In contrast, the ability of IFN-β to inhibit autoimmun
Publikováno v:
Journal of Neuroimmunology. 133:60-71
Interferon-beta is thought to provide clinical improvement to multiple sclerosis (MS) patients, in part, through its ability to suppress the generation of IL-12-dependent autoimmune T helper type 1 (Th1) cells by monocyte-derived dendritic cells (DC)
Autor:
Lili Farrokh-Siar, Kimm J. Hamann, Jean Maguire van Seventer, Henrietta Rajadurai, Ellen M. Palmer, S. C. Patel, Kourous A. Rezai, Gijs A. van Seventer, J. Terry Ernest
Publikováno v:
Current Eye Research. 24:206-213
To evaluate whether human fetal retinal pigment epithelial (HFRPE) cells express TRAIL (tumor necrosis factor related apoptosis inducing ligand). The role of TRAIL in HFRPE induced apoptosis was evaluated.Pure cultures of HFRPE cells were isolated. T
Autor:
Susan F. Law, Aric M. Franz, Gijs A. van Seventer, Jean Maguire van Seventer, Geraldine M. O'Neill, Steven B. Kanner, Erica A. Golemis, Maureen M. Mullen, Heinz J. Salmen
Publikováno v:
European Journal of Immunology. 31:1417-1427
Although beta1 integrin-dependent T cell migration is required for immune function, little is known of the signaling pathways regulating this migration. We now show that the cytoplasmic tyrosine kinase, focal adhesion kinase (FAK) plays an essential
Autor:
Taro Nagai, Bradford L. McRae, Gijs A. van Seventer, Jean Maguire van Seventer, Roshanak Tolouei Semnani
Publikováno v:
Blood. 96:210-217
Dendritic cell (DC) precursors and immature DC reside in epithelium where they encounter pathogens and cytokines, which stimulate their differentiation. We hypothesized that type-I interferons (IFN- and -β), cytokines that are produced early in t