Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jean M. T. van Griensven"'
Autor:
Gerard Dooijewaard, Linda G. M. Huisman, Rik C. Schoemaker, Ria Kroon, Kees Kluft, Jean M. T. van Griensven, Thea Stuurman, Adam F. Cohen
Publikováno v:
Clinical Pharmacology & Therapeutics. 60:504-511
Objective To investigate the influence of increased liver blood flow on the pharmacokinetics and pharmacodynamics of recombinant tissue-type plasminogen activator (rt-PA) and to study the changes in endogenous urokinase-type plasminogen activator (u-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c162f853f7c0b0a2abc54f864fa8b597
https://doi.org/10.1016/s0009-9236(96)90146-0
https://doi.org/10.1016/s0009-9236(96)90146-0
Autor:
Herman H. P. J. Lemkes, Christian J. Verhorst, Adam F. Cohen, William J. Jusko, Ria Kroon, Soong T. Chiang, Jean M. T. van Griensven
Publikováno v:
Clinical Pharmacology & Therapeutics. 58:631-640
Objectives To examine the effect of diabetes mellitus on the pharmacokinetics of tolrestat and to investigate its effect on red blood cell sorbitol levels according to a new pharmacodynamic model for this class of drugs. Methods Single and multiple d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f32c0c86a83ef3d005862179e283204
https://doi.org/10.1016/0009-9236(95)90019-5
https://doi.org/10.1016/0009-9236(95)90019-5
Autor:
Rik C. Schoemaker, W. A. Günzler, Horst Beier, Jean M. T. van Griensven, Kees Kluft, Linda G. M. Huisman, Joachim Gerloff, Ria Kroon, K. Burggraaf, Adam F. Cohen
Publikováno v:
Clinical pharmacology and therapeutics. 57(4)
Objective To investigate the influence of changes in liver blood flow on the pharmacokinetics and pharmacodynamics of single-chain unglycosylated urokinase-type plasminogen activator. Methods This open, randomized, crossover trial was carried out in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb0a14bb35d2840febbd0b900317d771
https://pubmed.ncbi.nlm.nih.gov/7712665
https://pubmed.ncbi.nlm.nih.gov/7712665