Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jean M. Daley"'
Autor:
Meredith J Crane, Jean M Daley, Olivier van Houtte, Samielle K Brancato, William L Henry, Jorge E Albina
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86660 (2014)
The origin of wound repair macrophages is incompletely defined and was examined here in sterile wounds using the subcutaneous polyvinyl alcohol sponge implantation model in mice. Phenotypic analysis identified F4/80(+)Ly6C(hi)CD64(+)MerTK(-) monocyte
Externí odkaz:
https://doaj.org/article/e72814f47ae34c9197913c5f94d8d480
Autor:
Gideon Koren, Kevin R. Murphy, Patrick J. Morrissey, Nilüfer N. Turan, Karuppiah Arunachalam, Lorraine Schofield, J. Dawn Abbott, Jean M. Daley
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 312:H959-H967
The incidence of both myocardial infarction (MI) and sudden cardiac death increases with age. Here, we describe the development of a minimally invasive large animal model of MI that can be applied to young or aged animals. We demonstrate that rabbit
Autor:
Meredith J. Crane, Samielle K. Brancato, Edmond Sabo, Jonathan S. Reichner, Jorge E. Albina, Alan A. Thomay, Jean M. Daley
Publikováno v:
Wound Repair and Regeneration. 21:624-633
The role of Toll-like receptor 4 (TLR4) in the regulation of inflammation and fibrosis in sterile wounds was investigated in TLR4 signal-deficient (C3H/HeJ or TLR4(-/-) ) and control mice using the subcutaneously implanted polyvinyl alcohol sponge wo
Autor:
Mark W. Harty, Alan A. Thomay, Jonathan S. Reichner, Jean M. Daley, P.J. Worth, Leslie J. Shelton, Jorge E. Albina, Edmond Sabo
Publikováno v:
The American Journal of Pathology. 174:2129-2136
In this study, we investigated the role of interleukin (IL)-1 signaling in wound healing. IL-1 receptor type I (IL-1R) knockout (KO) mice showed reduced fibrosis in both cutaneous and deep tissue wounds, which was accompanied by a reduction in inflam
Autor:
Gideon Koren, Yukiko Kunitomo, Xuwen Peng, Tae Yun Kim, Joseph F. Yammine, Bum-Rak Choi, Yichun Lu, Jean M. Daley, Kamana Bist, Lorraine Schofield, Mayara Grizotte-Lake, Zhilin Qu
Publikováno v:
Biophysical Journal. 108(2)
Background: Patients with post myocardial infarction (MI) have increased incidence of ventricular arrhythmias. The slowly activating K+ channels (IKs) has been reported to be downregulated consistently but in different degrees in the post-MI hearts.
Autor:
Gideon Koren, Katja E. Odening, Kamana Bist, Dmitry Terentyev, Xuwen Peng, Weiyan Li, Alain Karma, Yichun Lu, Radmila Terentyeva, Colin M. Rees, Bum-Rak Choi, Leroy L. Cooper, Hitesh K. Jindal, Jean M. Daley
Publikováno v:
Circulation research. 115(11)
Rationale: Loss-of-function mutations in human ether go-go (HERG) potassium channels underlie long QT syndrome type 2 (LQT2) and are associated with fatal ventricular tachyarrhythmia. Previously, most studies focused on plasma membrane–related path
Publikováno v:
The FASEB Journal. 27
Autor:
Samielle K, Brancato, Alan A, Thomay, Jean M, Daley, Meredith J, Crane, Jonathan S, Reichner, Edmond, Sabo, Jorge E, Albina
Publikováno v:
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. 21(4)
The role of Toll-like receptor 4 (TLR4) in the regulation of inflammation and fibrosis in sterile wounds was investigated in TLR4 signal-deficient (C3H/HeJ or TLR4(-/-) ) and control mice using the subcutaneously implanted polyvinyl alcohol sponge wo
Publikováno v:
Journal of leukocyte biology. 87(1)
Wound macrophages exhibit a complex phenotype, which changes as the wound matures and develops independently of IL-4 or IL-13. The phenotype of wound macrophages has not been studied by direct examination of these cells, yet macrophages recruited to
Autor:
Jonathan S. Reichner, William L. Henry, Balduino Mastrofrancesco, Jean M. Daley, Jorge E. Albina
Publikováno v:
The FASEB Journal. 23