Výsledky vyhledávání - "Jean M Grant"

Akademický článek

Viral sequestration of antigen subverts cross presentation to CD8(+) T cells.

Autor: Eric F Tewalt, Jean M Grant, Erica L Granger, Douglas C Palmer, Neal D Heuss, Dale S Gregerson, Nicholas P Restifo, Christopher C Norbury

Publikováno v: PLoS Pathogens, Vol 5, Iss 5, p e1000457 (2009)

Virus-specific CD8(+) T cells (T(CD8+)) are initially triggered by peptide-MHC Class I complexes on the surface of professional antigen presenting cells (pAPC). Peptide-MHC complexes are produced by two spatially distinct pathways during virus infect

Externí odkaz: https://doaj.org/article/0c88fc6736a94c98b98d402d66bd3a91

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Validated protocol for FoxP3 reveals increased expression in type 1 diabetes patients

Autor: Vicki Seyfert-Margolis, Alexis Conway, Paul K. Wallace, Stephen S. Wallace, Dalin Pan, Jean M. Grant, Katarzyna Bourcier

Publikováno v: Cytometry Part B: Clinical Cytometry. :69-78

Background: FoxP3 has become a key identifier of regulatory T cells. Investigators have used a variety of antibodies and methods for detecting FoxP3 by flow cytometry. To standardize FoxP3 antibody staining for use in clinical trial samples, we teste

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9887634f47ff91525190dd01357f3a87
https://doi.org/10.1002/cyto.b.20446

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Cross-priming utilizes antigen not available to the direct presentation pathway

Autor: Douglas C. Palmer, Keri B. Donohue, Nicholas P. Restifo, Christopher C. Norbury, Eric F. Tewalt, Jean M. Grant, Marc R. Theoret

Publikováno v: Immunology. 119:63-73

CD8+ T cells play a crucial role in protective immunity to viruses and tumours. Antiviral CD8+ T cells are initially activated by professional antigen presenting cells (pAPCs) that are directly infected by viruses (direct-priming) or following uptake

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1baaa83fafd958c0328d06eac10bca6d
https://doi.org/10.1111/j.1365-2567.2006.02406.x

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Viral sequestration of antigen subverts cross presentation to CD8(+) T cells

Autor: Christopher C. Norbury, Eric F. Tewalt, Nicholas P. Restifo, Neal D. Heuss, Dale S. Gregerson, Jean M. Grant, Erica L. Granger, Douglas C. Palmer

Publikováno v: PLoS Pathogens, Vol 5, Iss 5, p e1000457 (2009)
PLoS Pathogens

Virus-specific CD8+ T cells (TCD8+) are initially triggered by peptide-MHC Class I complexes on the surface of professional antigen presenting cells (pAPC). Peptide-MHC complexes are produced by two spatially distinct pathways during virus infection.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b0e712f4c2019caf28cf265f7378ae
http://europepmc.org/articles/PMC2680035?pdf=render

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Viral Sequestration of Antigen Subverts Cross Priming (93.14)

Autor: Eric Franklin Tewalt, Jean M Grant, Erica L Granger, Keri B Donohue, Chris C Norbury

Publikováno v: The Journal of Immunology. 178:S168-S168

Antigens driven by poxvirus late promoters are produced in much larger quantities than those driven by early promoters both in vitro and in vivo. Despite the abundance of protein produced, antigens driven by late poxvirus promoters typically induce a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f953386115436bce2a15f8e195c3a2af
https://doi.org/10.4049/jimmunol.178.supp.93.14

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