Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Jean M, Schmidt"'
Publikováno v:
Bergey's Manual of Systematics of Archaea and Bacteria. :1-23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8f73c20ebb0254bb45889d0b7110f0f
https://doi.org/10.1002/9781118960608.gbm00786
https://doi.org/10.1002/9781118960608.gbm00786
Autor:
Jean M. Schmidt, Suzanne V. Kelly
Publikováno v:
Bergey's Manual of Systematics of Archaea and Bacteria. :1-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::481ee6adf35f26fdfbf1c92beffe0c59
https://doi.org/10.1002/9781118960608.gbm00827
https://doi.org/10.1002/9781118960608.gbm00827
Autor:
Jean M. Schmidt, Fiona Hogan, Jean-Charles Chapuis, Ernest Hamel, George R. Pettit, Robin K. Pettit, Bryan R. Moser, Sandy Pon, Sonja Wolf
Publikováno v:
Bioorganic & Medicinal Chemistry. 17:6606-6612
As part of a broad-based SAR investigation of E-resveratrol (strong sirtuin activator and antineoplastic) and the anticancer vascular-targeting combretastatin-type stilbenes, a series of twenty-three beta-E-nitrostyrenes was synthesized in order to e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5c3db2fa522805d5774d4bf433d169
https://doi.org/10.1016/j.bmc.2009.07.076
https://doi.org/10.1016/j.bmc.2009.07.076
Autor:
Cherry L. Herald, Rui Tan, Jean-Charles Chapuis, Larry P. Tackett, Denise Nielsen Tackett, Jiang Du, Jean M. Schmidt, Toshihiko Nogawa, Justin Searcy, Qinghua Ye, Animesh Goswami, Gordon M. Cragg, John N. A. Hooper, Michael S. Hoard, Lee Williams, Dennis L. Doubek, Robin K. Pettit, Felicia M. Craciunescu, Fiona Hogan, George R. Pettit, Zbigniew A. Cichacz, Jun-Ping Xu
Publikováno v:
Journal of Natural Products. 71:438-444
Bioassay-guided fractionation of extracts of various plants, marine organisms, and microorganisms has led to the discovery of new natural sources of a number of known compounds that have significant biological activity. The isolation of interesting a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d5b60ce5fc1ae387985d7ee5ca6ac5f
https://doi.org/10.1021/np700738k
https://doi.org/10.1021/np700738k
Autor:
Jean M. Schmidt, George R. Pettit, Ernest Hamel, D. L. Herald, Monte R. Rhodes, Robin K. Pettit
Publikováno v:
Journal of Medicinal Chemistry. 48:4087-4099
A series of cis- and trans-stilbenes related to combretastatin A-4 (1a), with a variety of substituents at the 3‘-position of the aryl B-ring, were synthesized and evaluated for inhibitory activity employing six human cancer cell lines (NCI-H460 lu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::308feab31a2ecaf0ccc197560b215e7d
https://doi.org/10.1021/jm0205797
https://doi.org/10.1021/jm0205797
Autor:
Jean-Charles Chapuis, George R. Pettit, Jean M. Schmidt, Dennis L. Doubek, Robin K. Pettit, Veronique Pinilla, Qingwen Zhang, John C. Knight, Holger Hoffmann
Publikováno v:
Journal of Natural Products. 68:729-733
Using bioactivity-directed isolation procedures, three new spirostanol saponins designated sansevierin A (1), sansevistatin 1 (2), and sansevistatin 2 (3) were isolated (10-5 % yield) from the CH3OH−CH2Cl2 extract of Sansevieria ehrenbergii, accomp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e73b65e4ad0557640305aea6965a1af
https://doi.org/10.1021/np040203r
https://doi.org/10.1021/np040203r
Autor:
Jean-Charles Chapuis, Delbert L. Herald, Dennis L. Doubek, Jean M. Schmidt, Sylvie Ducki, George R. Pettit
Publikováno v:
Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics. 15:11-20
Two bromopyrrole marine alkaloids were isolated from the Mexican sponge, Agelas sp.: hymenidin (1) and agelastatin A (2). The structures were elucidated by analysis of their spectroscopic data and found to correspond to those in the literature. The a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dfca3ba0eda79e38926b88e8b692445
https://doi.org/10.3727/096504005775082075
https://doi.org/10.3727/096504005775082075
Autor:
Yung Chang, Holger Hoffmann, Larry V. Pearce, Peter M. Blumberg, Robin K. Pettit, Delbert L. Herald, Jean M. Schmidt, Ernest Hamel, Nancy E. Lewin, George R. Pettit
Publikováno v:
Journal of Medicinal Chemistry. 47:1775-1782
The marine sponge constituent aaptamine (1) has been converted to the cancer cell growth inhibitor and antibiotic designated hystatin 2 (8a). Herein, we also report results of an initial SAR evaluation of new benzyl derivatives of aaptamine (1). Sing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f09b262dabeeacf2af619b54c9193b0d
https://doi.org/10.1021/jm030070r
https://doi.org/10.1021/jm030070r
Autor:
George R. Pettit, Animesh Goswami, Takeshi Yamada, Atsushi Numata, Chika Iwamoto, Paul J. Clewlow, Hideaki Morito, Jean M. Schmidt, Gordon M. Cragg
Publikováno v:
Journal of Natural Products. 65:1886-1891
The bark of the giant neem tree Melia dubia was found to contain 11 euphane-type triterpenes. Five new compounds, meliastatins 1−5 (1−5), proved to inhibit growth of the P388 lymphocytic leukemia cell line (ED50 1.7−5.6 μg/mL). Four of the oth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f5c3c7814bdadf47d778fa148ae928d
https://doi.org/10.1021/np020216+
https://doi.org/10.1021/np020216+