Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Jean Luc Poyet"'
Autor:
Manuela C. Aguirre-Botero, Eduardo Aliprandini, Anisha Gladston, Olga Pacios, Rafael Miyazawa Martins, Jean-Luc Poyet, Rogerio Amino
Publikováno v:
Microorganisms, Vol 12, Iss 3, p 480 (2024)
Membranolytic molecules constitute the first line of innate immune defense against pathogenic microorganisms. Plasmodium sporozoites are potentially exposed to these cytotoxic molecules in the hemolymph and salivary glands of mosquitoes, as well as i
Externí odkaz:
https://doaj.org/article/4f5d4429d3264601ad82e325d1de34de
Autor:
Natesh Singh, Philippe Vayer, Shivalika Tanwar, Jean-Luc Poyet, Katya Tsaioun, Bruno O. Villoutreix
Publikováno v:
Frontiers in Drug Discovery, Vol 3 (2023)
Finding new drugs usually consists of five main stages: 1) a pre-discovery stage in which basic research is performed to try to understand the mechanisms leading to diseases and propose possible targets (e.g., proteins); 2) the drug discovery stage,
Externí odkaz:
https://doaj.org/article/6f2a514b24314b60a120d3a18a156d8f
Autor:
Hafsia Abbas, Dalia Kheira Derkaoui, Louise Jeammet, Emilie Adicéam, Jérôme Tiollier, Hélène Sicard, Thorsten Braun, Jean-Luc Poyet
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 136 (2024)
Apoptosis, or programmed cell death, is a fundamental process that maintains tissue homeostasis, eliminates damaged or infected cells, and plays a crucial role in various biological phenomena. The deregulation of apoptosis is involved in many human d
Externí odkaz:
https://doaj.org/article/b08ffce44d49476b993797e7ae02aaa3
Autor:
Laertty Garcia de Sousa Cabral, Cyntia Silva Oliveira, Katielle Albuquerque Freire, Monique Gonçalves Alves, Vani Xavier Oliveira, Jean-Luc Poyet, Durvanei Augusto Maria
Publikováno v:
Cancers, Vol 15, Iss 22, p 5342 (2023)
Breast cancer is the most common cancer in women, the so-called “Triple-Negative Breast Cancer” (TNBC) subtype remaining the most challenging to treat, with low tumor-free survival and poor clinical evolution. Therefore, there is a clear medical
Externí odkaz:
https://doaj.org/article/93b360d8c69e4e6682c0efb26e592b33
Autor:
Laertty Garcia de Sousa Cabral, Henrique Hesse, Katielle Albuquerque Freire, Cyntia Silva de Oliveira, Cibele Nicolaski Pedron, Monique Gonçalves Alves, Julio Pacheco Carlstron, Jean-Luc Poyet, Vani X. Oliveira, Jr, Durvanei A. Maria
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 153, Iss , Pp 113398- (2022)
Triple-negative breast cancer is the most aggressive subtype of breast cancer, with worse clinical evolution and tumor-free survival, leading to the need to develop new effective therapies for its control. The present study evaluated the action of tu
Externí odkaz:
https://doaj.org/article/500cfb582cdd4cfc8f3d361b1885dfe4
Autor:
Justine Habault, Nicolas Thonnart, Caroline Ram-Wolff, Martine Bagot, Armand Bensussan, Jean-Luc Poyet, Anne Marie-Cardine
Publikováno v:
Cells, Vol 11, Iss 19, p 2933 (2022)
Sézary syndrome (SS) is an aggressive cutaneous T cell lymphoma with poor prognosis mainly characterized by the expansion of a tumor CD4+ T cell clone in both skin and blood. So far, the development of new therapeutic strategies has been hindered by
Externí odkaz:
https://doaj.org/article/a11a96cdd8684b188c954f9c448134c6
Autor:
Gabriel Ichim, Benjamin Gibert, Sahil Adriouch, Catherine Brenner, Nathalie Davoust, Solange Desagher, David Devos, Svetlana Dokudovskaya, Laurence Dubrez, Jérôme Estaquier, Germain Gillet, Isabelle Guénal, Philippe P. Juin, Guido Kroemer, Patrick Legembre, Romain Levayer, Stéphen Manon, Patrick Mehlen, Olivier Meurette, Olivier Micheau, Bernard Mignotte, Florence Nguyen-Khac, Nikolay Popgeorgiev, Jean-Luc Poyet, Muriel Priault, Jean-Ehrland Ricci, Franck B. Riquet, Santos A. Susin, Magali Suzanne, Pierre Vacher, Ludivine Walter, Bertrand Mollereau
Publikováno v:
Biomolecules, Vol 12, Iss 7, p 901 (2022)
Since the Nobel Prize award more than twenty years ago for discovering the core apoptotic pathway in C. elegans, apoptosis and various other forms of regulated cell death have been thoroughly characterized by researchers around the world. Although ma
Externí odkaz:
https://doaj.org/article/a7116fd2eb2845b5911a169d405c21e9
Autor:
Laertty Garcia de Sousa Cabral, Cyntia Silva de Oliveira, Rosely Cabette Barbosa Alves, Vani Xavier Oliveira Jr., Jean-Luc Poyet, Durvanei Augusto Mari
Publikováno v:
Archives of Breast Cancer. :148-158
Background: Breast cancer is one of the most common diseases among women worldwide. The triple negative subtype is the most aggressive, with low tumor-free survival and the worst clinical evolution, requiring the development of more effective and tar
Autor:
Justine Habault, Anna Kaci, Ewa Pasquereau-Kotula, Claire Fraser, Christine Chomienne, Hervé Dombret, Thorsten Braun, Marika Pla, Jean-Luc Poyet
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Despite considerable progress, the treatment of acute leukemia continues to be a challenge for a significant majority of patients. Using a well-characterized preclinical mouse model of acute promyelocytic leukemia (APL), we evaluated here the antileu
Externí odkaz:
https://doaj.org/article/4d272b7d0ff046cea248fea3644850ce
Autor:
Jean-Luc Poyet, Heriberto Bruzzoni-Giovanelli, Bruno O. Villoutreix, Ewa Kotula, Léonard Jagot-Lacoussiere
AAC-11 is an antiapoptotic protein that is upregulated in most cancer cells. Increased expression of AAC-11 confers a survival advantage when cancer cells are challenged with various stresses and contributes to tumor invasion and metastases, whereas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d70ed9ffdd44691a6c053039926214a9
https://doi.org/10.1158/0008-5472.c.6508688.v1
https://doi.org/10.1158/0008-5472.c.6508688.v1