Zobrazeno 1 - 10
of 298
pro vyhledávání: '"Jean Luc Darlix"'
Autor:
Hugues de Rocquigny, Virgile Rat, Florentin Pastor, Jean Luc Darlix, Christophe Hourioux, Philippe Roingeard
Publikováno v:
Viruses, Vol 12, Iss 7, p 738 (2020)
The morphogenesis of Hepatitis B Virus (HBV) viral particles is nucleated by the oligomerization of HBc protein molecules, resulting in the formation of an icosahedral capsid shell containing the replication-competent nucleoprotein complex made of th
Externí odkaz:
https://doaj.org/article/9d6b3f9b12314e9584ba31cb22ef3ad6
Autor:
Jean-Luc Darlix, Author
Through an investigation of the nucleocapsid protein of the AIDS virus, this book illustrates how a small disordered basic viral protein controls virus structure, replication and genetic variability. It also highlights novel concepts indicating that
Publikováno v:
Retrovirology, Vol 19, Iss 1, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/68e22ee89a4842ee9e78790ca7c08c0e
Publikováno v:
Virologie (Montrouge, France). 13(5)
The human immunodeficiency viruses (HIV) are the etiologic agents of AIDS. Two types of HIV exist, essentially derived from independent events of transmission of monkey viruses to man, HIV-1 and HIV-2. These viruses differ with respect to their genet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4b632a0ca0d6f516ce728c1371bd76d9
https://pubmed.ncbi.nlm.nih.gov/36151619
https://pubmed.ncbi.nlm.nih.gov/36151619
Autor:
Richard Lathe, Jean-Luc Darlix
Publikováno v:
Archives of Virology
Lathe, R & Darlix, J-L 2020, ' Prion protein PrP nucleic acid binding and mobilization implicate retroelements as the replicative component of transmissible spongiform encephalopathy ', Archives of Virology, vol. 165, pp. 535–556 . https://doi.org/10.1007/s00705-020-04529-2
Lathe, R & Darlix, J-L 2020, ' Prion protein PrP nucleic acid binding and mobilization implicate retroelements as the replicative component of transmissible spongiform encephalopathy ', Archives of Virology, vol. 165, pp. 535–556 . https://doi.org/10.1007/s00705-020-04529-2
The existence of more than 30 strains of transmissible spongiform encephalopathy (TSE) and the paucity of infectivity of purified PrPSc, as well as considerations of PrP structure, are inconsistent with the protein-only (prion) theory of TSE. Nucleic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d82be8575fb6f2c1530a1e7bfc88c595
https://doi.org/10.1007/s00705-020-04529-2
https://doi.org/10.1007/s00705-020-04529-2
Publikováno v:
Viruses, Vol 2, Iss 4, Pp 939-960 (2010)
This mini-review summarizes the process of reverse-transcription, an obligatory step in retrovirus replication during which the retroviral RNA/DNA-dependent DNA polymerase (RT) copies the single-stranded genomic RNA to generate the double-stranded vi
Externí odkaz:
https://doaj.org/article/915dab20e4af4d14be87f46ca46c85e8
Publikováno v:
Viruses; Volume 14; Issue 3; Pages: 606
Retroviruses package two copies of their genomic RNA (gRNA) as non-covalently linked dimers. Many studies suggest that the retroviral nucleocapsid protein (NC) plays an important role in gRNA dimerization. The upper part of the L3 RNA stem-loop in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cd27d70b43b38e6b9abfe0c9deecd2d
https://doi.org/10.3390/v14030606
https://doi.org/10.3390/v14030606
Multiple Functions and Disordered Nature of Nucleocapsid Proteins of Retroviruses and Hepadnaviruses
Autor:
Hugues de Rocquigny, Jean-Luc Darlix
Publikováno v:
Viruses and Viral Infections in Developing Countries
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a47b0f6ec800560fc353269fe324d5c6
http://www.intechopen.com/articles/show/title/multiple-functions-and-disordered-nature-of-nucleocapsid-proteins-of-retroviruses-and-hepadnaviruses
http://www.intechopen.com/articles/show/title/multiple-functions-and-disordered-nature-of-nucleocapsid-proteins-of-retroviruses-and-hepadnaviruses
Autor:
Françoise Barré-Sinoussi, Jean-Luc Darlix, Philippe Roussel, Serge Bouaziz, Jean-François Delfraissy, Nathalie Chazal, Hugues de Rocquigny
Publikováno v:
Retrovirology
Retrovirology, BioMed Central, 2020, 17 (1), pp.9. ⟨10.1186/s12977-020-00518-0⟩
Retrovirology, Vol 17, Iss 1, Pp 1-4 (2020)
Retrovirology, BioMed Central, 2020, 17 (1), ⟨10.1186/s12977-020-00518-0⟩
Retrovirology, 2020, 17 (1), pp.9. ⟨10.1186/s12977-020-00518-0⟩
Retrovirology, BioMed Central, 2020, 17 (1), pp.9. ⟨10.1186/s12977-020-00518-0⟩
Retrovirology, Vol 17, Iss 1, Pp 1-4 (2020)
Retrovirology, BioMed Central, 2020, 17 (1), ⟨10.1186/s12977-020-00518-0⟩
Retrovirology, 2020, 17 (1), pp.9. ⟨10.1186/s12977-020-00518-0⟩
International audience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d60fd2223b3e2513442a9a66806d3139
https://hal.archives-ouvertes.fr/hal-02914650
https://hal.archives-ouvertes.fr/hal-02914650
Autor:
Jean-Luc Darlix, Richard Lathe
Publikováno v:
Lathe, R & Darlix, J-L 2017, ' Prion Protein PRNP: A New Player in Innate Immunity? – The Abeta Connection ', vol. 1, no. 1 . https://doi.org/10.3233/ADR-170037
Journal of Alzheimer's Disease Reports
Journal of Alzheimer's Disease Reports
The prion protein PRNP has been centrally implicated in the transmissible spongiform encephalopathies (TSEs), but its normal physiological role remains obscure. We highlight emerging evidence that PRNP displays antimicrobial activity, inhibiting the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8636932992b0993bfb4320f894ee3439
https://doi.org/10.3233/adr-170037
https://doi.org/10.3233/adr-170037