Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jean Louis Maurel"'
Publikováno v:
Thermochimica Acta. 408:85-96
Thermogravimetric analysis was used to study the sublimation and vaporisation processes of S(−) efaroxan hydrochloride, a potent and highly selective α-2-adrenoreceptor antagonist. The kinetic parameters of the sublimation were investigated by con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ced5d1814572ed4fd59c5b4354a51af
https://doi.org/10.1016/s0040-6031(03)00321-6
https://doi.org/10.1016/s0040-6031(03)00321-6
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 53:123-131
We have shown that efaxoran hydrochloride and efaxoran hydrobromide form solid solution over the entire range of compositions. The small values of enthalpy of mixing indicate that the system is close to ideality. Consequently, Oonk's method was used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a6f7a17786df02eecbd36f8fafa8d16
https://doi.org/10.1023/a:1010159402692
https://doi.org/10.1023/a:1010159402692
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 53:697-709
The phase diagram of R(+)-S(-) efaroxan hydrochloride (Tfus.(R)=245.1±0.3°C. ΔHfus.(R)=119.6±3.0 J g-1) shows a racemic compound. The melting temperature and melting enthalpy of the compound are: Tfus.(RS)=247.8±0.2°C and ΔHfus. (RS)=124.6±2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c82fdd243f62b8eb2bc2870fea38607
https://doi.org/10.1023/a:1010118122750
https://doi.org/10.1023/a:1010118122750
Autor:
Laure Monconduit, Jean-Louis Maurel, Claude Belin, Monique Tillard, Serge Brunel, Jean-Paul Ribet
Publikováno v:
Scopus-Elsevier
The title compound, C 11 H 13 N 2 O 2 + .Br - , crystallizes in the P2 1 2 1 2 1 space group. The absolute configuration of the therapeutically active molecule idazoxan [2-(1,4-benzodioxan-2-yl)imidazoline] could be resolved in this hydrobromide salt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58e6725f5227ae6d5a3d411df4e80bc0
https://doi.org/10.1107/s0108270198013286
https://doi.org/10.1107/s0108270198013286
Autor:
Adrian Newman-Tancredi, Bernard Vacher, Francis Colpaert, Jean Louis Maurel, Philippe Funes, Jean-Marie Autin
Publikováno v:
Journal of medicinal chemistry. 50(20)
We report the discovery of novel 5-HT1A receptor agonists and describe the process that led to the antidepressant candidate 9 (F 15599). 9 has nanomolar affinity for 5-HT1A binding sites and is over 1000-fold selective with respect to the other 5-HT1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b2e915c93311e0b1be03969cd950e5e
https://pubmed.ncbi.nlm.nih.gov/17803293
https://pubmed.ncbi.nlm.nih.gov/17803293
Autor:
Jean-Paul Ribet, B. Bonnaud, Claude Belin, B. Vacher, F. Colpaert, Monique Tillard, Jean-Louis Maurel, R. Pena
Publikováno v:
Spectrochimica Acta Part A : Molecular Spectroscopy [1967-1993]
Spectrochimica Acta Part A : Molecular Spectroscopy [1967-1993], Elsevier, 2005, 62 (1-3), pp.353-363. ⟨10.1016/j.saa.2005.01.002⟩
Spectrochimica Acta Part A : Molecular Spectroscopy [1967-1993], Elsevier, 2005, 62 (1-3), pp.353-363. ⟨10.1016/j.saa.2005.01.002⟩
{[1-(3-Chloro-4-fluorobenzoyl)-4-fluoropiperidin-4yl]methyl}[(5-methylpyridin-2-yl)methyl]amine, fumaric acid salt (C(20)H(22)ClF(2)N(3)O, C(4)H(4)O(4)) (1) was synthesized and characterized by the complete (1)H, (13)C and (19)F NMR analyses. The con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4180eceaa3abbc26c3ff919fe5b65af
https://hal.archives-ouvertes.fr/hal-00383121
https://hal.archives-ouvertes.fr/hal-00383121
Publikováno v:
Acta Crystallographica Section C Crystal Structure Communications. 51:2439-2441
The isomorphous structures of 2-[2-(2-ethyl-2,3-dihydro-2-benzofuranyl)]-2-imidazolinium [(+)-efaroxan cation] chloride, C 13 H 17 N 2 O + .Cl - , and bromide, C 13 H 17 N 2 O + .-Br-, have been determined. The absolute configuration of the active mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d00f45a12fe2962bd55d900b2607b342
https://doi.org/10.1107/s0108270195006706
https://doi.org/10.1107/s0108270195006706
Publikováno v:
Acta crystallographica. Section C, Crystal structure communications. 57(Pt 4)
The title compound, C(12)H(14)FN(2)O(3)(+).Br(-), crystallizes in the non-centrosymmetric P2(1)2(1)2(1) space group. The absolute configuration of the pharmacologically active molecule could be resolved in the hydrobromide salt, the structure of whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a76562b474f38046dd7235cef067fc89
https://pubmed.ncbi.nlm.nih.gov/11313601
https://pubmed.ncbi.nlm.nih.gov/11313601
Autor:
Jean-Marie Autin, Alain Chauvet, Jean-François Patoiseau, Joël Jaud, Jacqueline Masse, D C Bigg, Jean-Louis Maurel, Jean-Paul Ribet
Publikováno v:
Journal of pharmaceutical sciences. 81(8)
The characterization of two polymorphs of the title compound (F2692; 1) by differential scanning calorimetry (DSC), microanalysis, proton nuclear magnetic resonance spectroscopy, thermogravimetry, thermomicroscopy, infrared spectroscopy, and X-ray di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c621e5cd9a56184b1b07fd0953cfe3bf
https://pubmed.ncbi.nlm.nih.gov/1357154
https://pubmed.ncbi.nlm.nih.gov/1357154
Publikováno v:
Acta Crystallographica Section C Crystal Structure Communications. 54:IUC9800004
In the title compound, C13H17N2O+.Cl−, homochiral cationic molecules are linked to form chains in the b-direction of the triclinic cell by N—H⋯Cl hydrogen bonds. The dihydro-2-furanyl groups are nearly parallel to the a axis [81.7 (1)° between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0156cf6ccc2d02cb1fcddcc34e9ae8f6
https://doi.org/10.1107/s0108270198099818
https://doi.org/10.1107/s0108270198099818