Zobrazeno 1 - 10
of 216
pro vyhledávání: '"Jean Lachaine"'
Publikováno v:
Current Oncology, Vol 30, Iss 5, Pp 4483-4498 (2023)
Background: Continuous oral targeted therapies (OTT) represent a major economic burden on the Canadian healthcare system, due to their high cost and administration until disease progression/toxicity. The recent introduction of venetoclax-based fixed-
Externí odkaz:
https://doaj.org/article/08d96d2b8ab0478382bdb92987667731
Autor:
Kimberly Guinan, Karine Mathurin, Yunghan Au, Andre C. Schuh, Cat N. Bui, Xinglei Chai, Jean Lachaine
Publikováno v:
Current Oncology, Vol 29, Iss 10, Pp 7524-7536 (2022)
Treatment for acute myeloid leukemia (AML) typically involves intensive chemotherapy (IC); however, there is an unmet need for approximately 50% of AML patients who are deemed unfit or ineligible for IC. The purpose of this study was to evaluate, fro
Externí odkaz:
https://doaj.org/article/bf0b243931014d68b508d082835e8efb
Autor:
Jean Lachaine, Catherine Beauchemin, Kimberly Guinan, Philippe Thebault, Andrew Aw, Versha Banerji, Isabelle Fleury, Carolyn Owen
Publikováno v:
Current Oncology, Vol 28, Iss 1, Pp 332-345 (2021)
Background: Continuous oral targeted therapy (OTT) for chronic lymphocytic leukemia (CLL) represents an effective therapy but also a major economic burden on the healthcare system. This study aimed to estimate future direct costs, along with the prev
Externí odkaz:
https://doaj.org/article/4cb8792bbcc348f8a927618a83a11e85
Publikováno v:
JMIR Research Protocols, Vol 11, Iss 3, p e35461 (2022)
BackgroundType 2 diabetes mellitus (T2DM) imposes a substantial burden owing to its increasing prevalence and life-threatening complications. In patients who do not achieve glycemic targets with oral antidiabetic drugs, the initiation of insulin is r
Externí odkaz:
https://doaj.org/article/5ec6cce21b224b8280e5a4ff8841b00c
Autor:
Véronique Baribeau, Connie J Kim, René-Pierre Lorgeoux, Josée Brisebois, Harout Tossonian, Jean Lachaine
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0262645 (2022)
There is limited understanding on healthcare utilization and costs of age-related comorbidities such as cardiovascular, bone and renal disease/disorder in people living with human immunodeficiency virus, so we compared comorbidity prevalence and asso
Externí odkaz:
https://doaj.org/article/9a2f7d6738864e0e892abb8dc160158b
Autor:
Alan N Barkun, Ralph Crott, Carlo A Fallone, Wendy A Kennedy, Jean Lachaine, Carey Levinton, David Armstrong, Naoki Chiba, Alan Thomson, Sander Veldhuyzen van Zanten, Paul Sinclair, Sergio Escobedo, Bijan Chakraborty, Sandra Smyth, Robert White, Helen Kalra, Krista Nevin
Publikováno v:
Canadian Journal of Gastroenterology, Vol 24, Iss 8, Pp 489-498 (2010)
BACKGROUND: The cost-effectiveness of initial strategies in managing Canadian patients with uninvestigated upper gastrointestinal symptoms remains controversial.
Externí odkaz:
https://doaj.org/article/19e441294c494587b8a877ac6347323d
Publikováno v:
ClinicoEconomics and Outcomes Research. 15:295-308
Jean Lachaine,1,2 Jean-Nicolas Charron,2 Jean C Gregoire,3 Robert A Hegele,4 Lawrence A Leiter5 1University of Montreal, Montreal, QC, Canada; 2PeriPharm Inc., Montreal, QC, Canada; 3Institut de cardiologie de Montréal, Montreal, QC, Canada; 4Roba
Publikováno v:
Journal of Comparative Effectiveness Research. 11:57-64
Health state utilities (HSU) data collected in real-world evidence studies are at risk of bias. Although numerous guidance documents are available, practical advice to avoid bias in HSU studies is limited. Thus, the objective of this article was to d
Autor:
Martin Barbeau, Paul Harasymowycz, Catherine Royer, Katherine Jobin-Gervais, Jean Lachaine, Amy Xianying Cui, Catherine Beauchemin, K. Mathurin
Publikováno v:
British Journal of Ophthalmology. 106:640-647
Background/aimsTo assess the comparative efficacy of latanoprostene bunod (LBN), a novel prostaglandin analogue (PGA), to other medications for open-angle glaucoma and ocular hypertension on lowering intraocular pressure (IOP).MethodsA systematic lit
Autor:
Kimberly Guinan, Jean Lachaine, Nancy Paul Roc, Sarah-Jane Bull, Dipti Tankala, Stéphane Barakat, Christopher M. Hillis, Versha Banerji
Publikováno v:
Blood. 140:2157-2158