Protein Corona Composition of Silica Nanoparticles in Complex Media: Nanoparticle Size does not Matter

Autor: Laurent Marichal, Géraldine Klein, Jean Armengaud, Yves Boulard, Stéphane Chédin, Jean Labarre, Serge Pin, Jean-Philippe Renault, Jean-Christophe Aude

Publikováno v: Nanomaterials, Vol 10, Iss 2, p 240 (2020)

Biomolecules, and particularly proteins, bind on nanoparticle (NP) surfaces to form the so-called protein corona. It is accepted that the corona drives the biological distribution and toxicity of NPs. Here, the corona composition and structure were s

Externí odkaz: https://doaj.org/article/53a6465950a9416c95261dbe27ee79be

Protein–Nanoparticle Interactions: What Are the Protein–Corona Thickness and Organization?

Autor: Jean Philippe Renault, Jean-Christophe Aude, Serge Pin, Jean Labarre, Gaël Giraudon--Colas, Laurent Marichal, Antoine Thill, Fabrice Cousin, Yves Boulard

Publikováno v: Langmuir
Langmuir, American Chemical Society, 2019, 35 (33), pp.10831-10837. ⟨10.1021/acs.langmuir.9b01373⟩
Langmuir, 2019, 35 (33), pp.10831-10837. ⟨10.1021/acs.langmuir.9b01373⟩

International audience; Protein adsorption on a surface is generally evaluated in terms of the evolution of the proteins’ structures and functions. However, when the surface is that of a nanoparticle, the protein corona formed around it possesses a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7d370c1bf2a3bb62af7f161a2057205
https://doi.org/10.1021/acs.langmuir.9b01373

Peroxiredoxin promotes longevity and H2O2-resistance in yeast through redox-modulation of protein kinase A

Autor: Cecilia Picazo, Friederike Roger, Niek Welkenhuysen, Chunxia Gao, Marouane Libiad, Markus Hartl, Mikael Molin, Sarah Hanzén, Thomas Nyström, Gilles Lagniel, Chikako Asami, Jean Labarre, Morten Grøtli, Wolfgang Reiter, Michel B. Toledano

Publikováno v: eLife
eLife, 2020, 9, ⟨10.7554/eLife.60346⟩
eLife, eLife Sciences Publication, 2020, 9, ⟨10.7554/eLife.60346⟩
eLife, Vol 9 (2020)

Peroxiredoxins are H2O2scavenging enzymes that also carry out H2O2signaling and chaperone functions. In yeast, the major cytosolic peroxiredoxin, Tsa1 is required for both promoting resistance to H2O2and extending lifespan upon caloric restriction. W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a498c95cac033c52b0c6421af1404a07
https://doi.org/10.7554/elife.60346

Importance of Post-translational Modifications in the Interaction of Proteins with Mineral Surfaces: The Case of Arginine Methylation and Silica surfaces

Autor: Serge Pin, Jean Armengaud, Stéphane Chédin, Gilles Lagniel, Laurent Marichal, Yves Boulard, Jean-Christophe Aude, Géraldine Klein, Carine Tellier-Lebegue, Jean Philippe Renault, Jean Labarre

Publikováno v: Langmuir
Langmuir, 2018, 34 (18), pp.5312-5322. ⟨10.1021/acs.langmuir.8b00752⟩
Langmuir, American Chemical Society, 2018, 34 (18), pp.5312-5322. ⟨10.1021/acs.langmuir.8b00752⟩

International audience; Understanding the mechanisms involved in the interaction of proteins with inorganic surfaces is of major interest for both basic research and practical applications involving nanotechnology. From the list of cellular proteins

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56df3d8fbd6153d929fc342ed2fb67f7
https://cea.hal.science/cea-01858455

Glutathione is essential to preserve nuclear function and cell survival under oxidative stress

Autor: Peggy Baudouin-Cornu, Meng-Er Huang, Véronique Berthonaud, Stéphane Chédin, Gilles Lagniel, Elie Hatem, Jean Labarre, M. Dardalhon

Publikováno v: Free Radical Biology and Medicine. 67:103-114

Organisms growing in aerobic environments must cope with Reactive Oxygen Species (ROS). Although ROS damage all the cellular macromolecules, they play a central role in a range of biological processes requiring a tight control of redox homeostasis. I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e28dfcd716f7b2fc8a27b0defd5f5e6
https://doi.org/10.1016/j.freeradbiomed.2013.10.807