Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jean LJM Scheijen"'
Autor:
Nordin M.J. Hanssen, Chris Tikellis, Raelene J. Pickering, Dragana Dragoljevic, Man Kit Sam Lee, Tomasz Block, Jean LJM Scheijen, Kristiaan Wouters, Toshio Miyata, Mark E. Cooper, Andrew J. Murphy, Merlin C. Thomas, Casper G. Schalkwijk
Publikováno v:
Biomedicine and Pharmacotherapy, 158:114211. Elsevier Masson
Biomedicine & Pharmacotherapy, 158:114211. Elsevier Masson
Biomedicine & Pharmacotherapy, 158:114211. Elsevier Masson
Methylglyoxal (MGO) is a reactive glucose metabolite linked to diabetic cardiovascular disease (CVD). MGO levels surge during intermittent hyperglycemia. We hypothesize that these MGO spikes contribute to athero-sclerosis, and that pyridoxamine as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db7af6216845b02d39a90bef9d164c10
https://pure.amc.nl/en/publications/pyridoxamine-prevents-increased-atherosclerosis-by-intermittent-methylglyoxal-spikes-in-the-aortic-arches-of-apoe-mice(349c407c-bb6c-4364-aeaa-7d60a055fe8e).html
https://pure.amc.nl/en/publications/pyridoxamine-prevents-increased-atherosclerosis-by-intermittent-methylglyoxal-spikes-in-the-aortic-arches-of-apoe-mice(349c407c-bb6c-4364-aeaa-7d60a055fe8e).html
Autor:
Casper G. Schalkwijk, Carla J.H. van der Kallen, Katrien H.J. Gaens, Coen D.A. Stehouwer, Jean Ljm Scheijen, Dionne E. Maessen, Marleen M.J. van Greevenbroek
Publikováno v:
Journal of Diabetes & Metabolism. 5
Objective: Methylglyoxal (MGO), a highly reactive dicarbonyl compound generated by the spontaneous degradation of glycolytic intermediates, is a major precursor for advanced glycation endproducts and can potentially disrupt cellular functions. MGO ca