Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jean L. Sarcich"'
Autor:
Robert L. Heinrikson, A G Tomasselli, Donna J. Rothrock, June Lull, Jean L. Sarcich, Ana M. Mildner, Joseph W. Leone
Publikováno v:
Aspartic Proteinases ISBN: 9781461357612
Recently, we reported [1] a single step, large scale purification of recombinant HIV protease, wherein Escherichia coli inclusion bodies harboring the enzyme are dissolved in 50% acetic acid and the solution is subjected to size exclusion chromatogra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90ca8ab1f3b85fa071a45ea2396c67bc
https://doi.org/10.1007/978-1-4615-1871-6_62
https://doi.org/10.1007/978-1-4615-1871-6_62
Autor:
Jean L. Sarcich, Robert L. Heinrikson, June Lull, Donna J. Rothrock, Ana M. Mildner, A G Tomasselli, Joseph W. Leone
Publikováno v:
Aspartic Proteinases ISBN: 9781461357612
The essential role of the protease from human immunodeficiency virus (HIV) in the final maturation phase of the viral life cycle makes this enzyme an important target for the design of drugs that might be effective in the treatment of acquired immuno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b945f772673e84a993ffea33fee1a64c
https://doi.org/10.1007/978-1-4615-1871-6_51
https://doi.org/10.1007/978-1-4615-1871-6_51
Autor:
Linda J. Barrett, Alfredo G. Tomasselli, Satish K. Sharma, W. Jeffrey Howe, Robert L. Heinrikson, David B. Evans, I M Reardon, Jean L. Sarcich
A study has been made of the susceptibility of recombinant constructs of reverse transcriptase (RT) and ribonuclease H (RNase H) from human immunodeficiency virus type 1 (HIV-1) to digestion by the HIV-1 protease. At neutral pH, the protease attacks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d24a545bef62e38a1e3abd9bd9d0201
https://europepmc.org/articles/PMC2142316/
https://europepmc.org/articles/PMC2142316/