Zobrazeno 1 - 10
of 168
pro vyhledávání: '"Jean L. Nakamura"'
Autor:
Neal K. Bennett, Mai K. Nguyen, Maxwell A. Darch, Hiroki J. Nakaoka, Derek Cousineau, Johanna ten Hoeve, Thomas G. Graeber, Markus Schuelke, Emin Maltepe, Martin Kampmann, Bryce A. Mendelsohn, Jean L. Nakamura, Ken Nakamura
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Energy metabolism and ATP levels are controlled by an interlocking network of pathways. Here, the authors apply a genome-wide CRISPR screen to define genes that increase or decrease ATP levels to define the “ATPome”, a map of pathways that contri
Externí odkaz:
https://doaj.org/article/f277e255c7dc4504b568ae47fe3e9af8
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Single nucleotide variants (SNVs) identified in cancer genomes can be de-convolved using non-negative matrix factorization (NMF) into discrete trinucleotide-based mutational signatures indicative of specific cancer-causing processes. The sta
Externí odkaz:
https://doaj.org/article/18916e3fad1b4077bd253d4b9366ceb3
Autor:
Amy L. Sherborne, Philip R. Davidson, Katharine Yu, Alice O. Nakamura, Mamunur Rashid, Jean L. Nakamura
Publikováno v:
Cell Reports, Vol 12, Iss 11, Pp 1915-1926 (2015)
Ionizing radiation (IR) is a mutagen that promotes tumorigenesis in multiple exposure contexts. One severe consequence of IR is the development of second malignant neoplasms (SMNs), a radiotherapy-associated complication in survivors of cancers, part
Externí odkaz:
https://doaj.org/article/bf664187ca3341ecba3db78de02ccd58
Autor:
Penny K, Sneed, Jason W, Chan, Lijun, Ma, Steve E, Braunstein, Philip V, Theodosopoulos, Shannon E, Fogh, Jean L, Nakamura, Lauren, Boreta, David R, Raleigh, Benjamin P, Ziemer, Olivier, Morin, Shawn L, Hervey-Jumper, Michael W, McDermott
Publikováno v:
Journal of Neurosurgery. 138:104-112
OBJECTIVE The authors previously evaluated risk and time course of adverse radiation effects (AREs) following stereotactic radiosurgery (SRS) for brain metastases, excluding lesions treated after prior SRS. In the present analysis they focus specific
Resection with intraoperative cesium-131 brachytherapy as salvage therapy for recurrent brain tumors
Autor:
William C, Chen, Matthieu, Lafreniere, Christina, Phuong, S John, Liu, Joe D, Baal, Michael, Lometti, Olivier, Morin, Benjamin, Ziemer, Harish N, Vasudevan, Calixto-Hope G, Lucas, Shawn L, Hervey-Jumper, Philip V, Theodosopoulos, Stephen T, Magill, Shannon, Fogh, Jean L, Nakamura, Lauren, Boreta, Penny K, Sneed, Michael W, McDermott, David R, Raleigh, Steve E, Braunstein
Publikováno v:
Journal of Neurosurgery. 137:924-930
OBJECTIVE The authors’ objective was to examine the safety and efficacy of salvage intracranial cesium-131 brachytherapy in combination with resection of recurrent brain tumors. METHODS The authors conducted a retrospective chart review of consecut
Autor:
Anders I. Persson, William A. Weiss, Kevan M. Shokat, C. David James, Mitchel S. Berger, Jean L. Nakamura, Daniel W. Sirkis, Yvan H. Chanthery, Dustin J. Maly, Nan Li
Figure S2. Expression of potential targets of VX680 in human GBM cultures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ddf3541420f36394191db093577a2b7
https://doi.org/10.1158/1535-7163.22502434
https://doi.org/10.1158/1535-7163.22502434
Autor:
Jean L. Nakamura, Gary L. Johnson, Kevin Shannon, D. Wade Clapp, Sourav Bandyopadhyay, Ganesh Krishnamurthi, Hiroki J. Nakaoka, Chi Zhang, Benjamin Huang, Steven P. Angus, Daniela Pucciarelli
Supplementary Figure 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9059e9dd951ee033455a93e1ba63da9f
https://doi.org/10.1158/1535-7163.22518777.v1
https://doi.org/10.1158/1535-7163.22518777.v1
Autor:
Jean L. Nakamura, Gary L. Johnson, Kevin Shannon, D. Wade Clapp, Sourav Bandyopadhyay, Ganesh Krishnamurthi, Hiroki J. Nakaoka, Chi Zhang, Benjamin Huang, Steven P. Angus, Daniela Pucciarelli
Supplementary Table 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce466ec2f39826c2bcb41e0c1a2c4218
https://doi.org/10.1158/1535-7163.22518738
https://doi.org/10.1158/1535-7163.22518738
Autor:
Jean L. Nakamura, Gary L. Johnson, Kevin Shannon, D. Wade Clapp, Sourav Bandyopadhyay, Ganesh Krishnamurthi, Hiroki J. Nakaoka, Chi Zhang, Benjamin Huang, Steven P. Angus, Daniela Pucciarelli
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cd937f798c4b530b4b075f6af4fdb40
https://doi.org/10.1158/1535-7163.22518744.v1
https://doi.org/10.1158/1535-7163.22518744.v1
Autor:
Jean L. Nakamura, Gary L. Johnson, Kevin Shannon, D. Wade Clapp, Sourav Bandyopadhyay, Ganesh Krishnamurthi, Hiroki J. Nakaoka, Chi Zhang, Benjamin Huang, Steven P. Angus, Daniela Pucciarelli
Loss of the tumor suppressor NF1 leads to activation of RAS effector pathways, which are therapeutically targeted by inhibition of mTOR (mTORi) or MEK (MEKi). However, therapeutic inhibition of RAS effectors leads to the development of drug resistanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77b9200fd99429f0de8d13ec16a7d102
https://doi.org/10.1158/1535-7163.c.6542103
https://doi.org/10.1158/1535-7163.c.6542103