Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jean L Scheijen"'
Autor:
Marie-Julie Nokin, Florence Durieux, Paul Peixoto, Barbara Chiavarina, Olivier Peulen, Arnaud Blomme, Andrei Turtoi, Brunella Costanza, Nicolas Smargiasso, Dominique Baiwir, Jean L Scheijen, Casper G Schalkwijk, Justine Leenders, Pascal De Tullio, Elettra Bianchi, Marc Thiry, Koji Uchida, David A Spiegel, James R Cochrane, Craig A Hutton, Edwin De Pauw, Philippe Delvenne, Dominique Belpomme, Vincent Castronovo, Akeila Bellahcène
Publikováno v:
eLife, Vol 13 (2024)
Externí odkaz:
https://doaj.org/article/dfea8585ba3b4458899254c8dcbe41ae
Autor:
Bernardina T Fokkens, Douwe J Mulder, Casper G Schalkwijk, Jean L Scheijen, Andries J Smit, Leonoor I Los
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173379 (2017)
PURPOSE:Advanced glycation endproducts (AGEs) and their precursors α-dicarbonyls are implicated in the progression of diabetic retinopathy. The purpose of this study was to assess AGEs and α-dicarbonyls in the vitreous of patients with type 2 diabe
Externí odkaz:
https://doaj.org/article/2a71db7bbe094e1fac706c44f3e373bd
Autor:
Marie-Julie Nokin, Florence Durieux, Paul Peixoto, Barbara Chiavarina, Olivier Peulen, Arnaud Blomme, Andrei Turtoi, Brunella Costanza, Nicolas Smargiasso, Dominique Baiwir, Jean L Scheijen, Casper G Schalkwijk, Justine Leenders, Pascal De Tullio, Elettra Bianchi, Marc Thiry, Koji Uchida, David A Spiegel, James R Cochrane, Craig A Hutton, Edwin De Pauw, Philippe Delvenne, Dominique Belpomme, Vincent Castronovo, Akeila Bellahcène
Publikováno v:
eLife, Vol 5 (2016)
Metabolic reprogramming toward aerobic glycolysis unavoidably induces methylglyoxal (MG) formation in cancer cells. MG mediates the glycation of proteins to form advanced glycation end products (AGEs). We have recently demonstrated that MG-induced AG
Externí odkaz:
https://doaj.org/article/2e16f962425e42da9c3a326900bb4ea8
Autor:
Alaa Alkhalaf, Nanne Kleefstra, Klaas H Groenier, Henk J G Bilo, Reinold O B Gans, Peter Heeringa, Jean L Scheijen, Casper G Schalkwijk, Gerjan J Navis, Stephan J L Bakker
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40427 (2012)
Formation of advanced glycation endproducts (AGEs), endothelial dysfunction, and low-grade inflammation are intermediate pathways of hyperglycemia-induced vascular complications. We investigated the effect of benfotiamine on markers of these pathways
Externí odkaz:
https://doaj.org/article/8186d518d73a427caa525e64613a5384
Autor:
Danielle J. Borg, Pouya Faridi, Kai Lin Giam, Peta Reeves, Amelia K. Fotheringham, Domenica A. McCarthy, Sherman Leung, Micheal S. Ward, Brooke E. Harcourt, Rochelle Ayala, Jean L. Scheijen, David Briskey, Nadine L. Dudek, Casper G. Schalkwijk, Raymond Steptoe, Anthony W. Purcell, Josephine M. Forbes
Publikováno v:
Metabolites, Vol 11, Iss 7, p 426 (2021)
Mechanisms by which advanced glycation end products (AGEs) contribute to type 1 diabetes (T1D) pathogenesis are poorly understood. Since life-long pharmacotherapy with alagebrium chloride (ALT) slows progression to experimental T1D, we hypothesized t
Externí odkaz:
https://doaj.org/article/aa01d89ace73484cadb792438502955d
Autor:
Sherman S. Leung, Danielle J. Borg, Domenica A. McCarthy, Tamar E. Boursalian, Justen Cracraft, Aowen Zhuang, Amelia K. Fotheringham, Nicole Flemming, Thomas Watkins, John J. Miles, Per-Henrik Groop, Jean L. Scheijen, Casper G. Schalkwijk, Raymond J. Steptoe, Kristen J. Radford, Mikael Knip, Josephine M. Forbes
Publikováno v:
Diabetes, 71(9), 1994-2008. American Diabetes Association
Type 1 diabetes (T1D) is an autoimmune disease with no cure, where clinical translation of promising therapeutics has been hampered by the reproducibility crisis. Here, short-term administration of an antagonist to the receptor for advanced glycation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dd3e8333caaa65906e3300828b73aed
https://doi.org/10.2337/figshare.20051633.v1
https://doi.org/10.2337/figshare.20051633.v1
Autor:
Justine Bellier, Marie-Julie Nokin, Maurine Caprasse, Assia Tiamiou, Arnaud Blomme, Jean L. Scheijen, Benjamin Koopmansch, Gillian M. MacKay, Barbara Chiavarina, Brunella Costanza, Gilles Rademaker, Florence Durieux, Ferman Agirman, Naïma Maloujahmoum, Pino G. Cusumano, Pierre Lovinfosse, Hing Y. Leung, Frédéric Lambert, Vincent Bours, Casper G. Schalkwijk, Roland Hustinx, Olivier Peulen, Vincent Castronovo, Akeila Bellahcène
Publikováno v:
Cell Reports, 30(5), 1400-1416.e6. Cell Press
Cell Reports, Vol 30, Iss 5, Pp 1400-1416.e6 (2020)
Cell Reports, Vol 30, Iss 5, Pp 1400-1416.e6 (2020)
Summary: The use of cetuximab anti-epidermal growth factor receptor (anti-EGFR) antibodies has opened the era of targeted and personalized therapy in colorectal cancer (CRC). Poor response rates have been unequivocally shown in mutant KRAS and are ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::11eead07678672c11d9b92e97a445f08
https://pubmed.ncbi.nlm.nih.gov/32023458
https://pubmed.ncbi.nlm.nih.gov/32023458
Autor:
Justine Bellier, Marie-Julie Nokin, Maurine Caprasse, Assia Tiamiou, Arnaud Blomme, Jean L. Scheijen, Benjamin Koopmansch, Gillian M. MacKay, Barbara Chiavarina, Brunella Costanza, Gilles Rademaker, Florence Durieux, Ferman Agirman, Naïma Maloujahmoum, Pino G. Cusumano, Pierre Lovinfosse, Hing Y. Leung, Frédéric Lambert, Vincent Bours, Casper G. Schalkwijk, Roland Hustinx, Olivier Peulen, Vincent Castronovo, Akeila Bellahcène
Publikováno v:
Cell Reports, Vol 30, Iss 5, Pp 1400-1416.e6 (2020)
Summary: The use of cetuximab anti-epidermal growth factor receptor (anti-EGFR) antibodies has opened the era of targeted and personalized therapy in colorectal cancer (CRC). Poor response rates have been unequivocally shown in mutant KRAS and are ev
Externí odkaz:
https://doaj.org/article/96932a30ac1e4a57b60f7bff8ef7fecf
Autor:
Mitchell Bijnen, Marleen M. J. van Greevenbroek, Carla J. H. van der Kallen, Jean L. Scheijen, Marjo P. H. van de Waarenburg, Coen D. A. Stehouwer, Kristiaan Wouters, Casper G. Schalkwijk
Publikováno v:
Journal of Diabetes Research, Vol 2019 (2019)
Advanced glycation end products (AGEs) accumulate in fatty livers and may contribute to low-grade inflammation (LGI), potentially via their receptor, RAGE. It is unknown if the AGE accumulation in fatty livers results in elevated circulating AGEs. In
Externí odkaz:
https://doaj.org/article/009eb056902c40e5b87a3ba6266b9119