Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jean L, Tan"'
Autor:
Bhavana Nayer, Jean L. Tan, Yasmin K. Alshoubaki, Yen-Zhen Lu, Julien M. D. Legrand, Sinnee Lau, Nan Hu, Anthony J. Park, Xiao-Nong Wang, Daniela Amann-Zalcenstein, Peter F. Hickey, Trevor Wilson, Gisela A. Kuhn, Ralph Müller, Ajithkumar Vasanthakumar, Shizuo Akira, Mikaël M. Martino
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Regulatory T cells (Tregs) are crucial immune cells for tissue repair and regeneration. However, their potential as a cell-based regenerative therapy is not yet fully understood. Here, we show that local delivery of exogenous Tregs into inju
Externí odkaz:
https://doaj.org/article/f42f79ea96ac4536ad48ec4b75f69576
Autor:
Yasmin K. Alshoubaki, Bhavana Nayer, Yen-Zhen Lu, Ekaterina Salimova, Sin Nee Lau, Jean L. Tan, Daniela Amann-Zalcenstein, Peter F. Hickey, Gonzalo del Monte-Nieto, Ajithkumar Vasanthakumar, Mikaël M. Martino
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Regulatory T cells (Tregs) are key immune regulators that have shown promise in enhancing cardiac repair post-MI, although the mechanisms remain elusive. Here, we show that rapidly increasing Treg number in the circulation post-MI via system
Externí odkaz:
https://doaj.org/article/a905ba98718746ceb7e2cdf602aafd25
Autor:
Jean L. Tan, Blake Lash, Rezvan Karami, Bhavana Nayer, Yen-Zhen Lu, Celeste Piotto, Ziad Julier, Mikaël M. Martino
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Tan, Lash et al. show that blocking the Interleukin-1 receptor promotes rapid wound closure in diabetic mice. They engineered a matrix binding form of Interleukin-1 receptor antagonist (IL-1Ra) that has the ability of precise localisation and retenti
Externí odkaz:
https://doaj.org/article/d69e7e9bda4641d3aec93935b49ff999
Autor:
Gina D. Kusuma, Mehri Barabadi, Jean L. Tan, David A. V. Morton, Jessica E. Frith, Rebecca Lim
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Extracellular vesicles (EVs)-based therapeutics are based on the premise that EVs shed by stem cells exert similar therapeutic effects and these have been proposed as an alternative to cell therapies. EV-mediated delivery is an effective and efficien
Externí odkaz:
https://doaj.org/article/334be111ccaa4599a4d6ae32a3c498d0
Publikováno v:
Cell Transplantation, Vol 23 (2014)
Human amnion epithelial cells (hAECs) have been shown to modulate inflammation and restore normal lung structure and respiratory function following bleomycin challenge in immune-competent mice. These effects are exerted despite a lack of significant
Externí odkaz:
https://doaj.org/article/c87669dfcb1342c18dfde76ee0f246ba
Autor:
Sean V. Murphy, Suzane C. Shiyun, Jean L. Tan, Siow Chan, Graham Jenkin, Euan M. Wallace, Rebecca Lim
Publikováno v:
Cell Transplantation, Vol 21 (2012)
Since current treatments for both acute and chronic lung diseases are less than ideal, there has been recent interest in the use of cell-based therapies for inflammatory lung disease. Specifically, human amnion epithelial cells (hAECs) have been show
Externí odkaz:
https://doaj.org/article/eef807536a104a979a6c49ae3d7dc0ce
Autor:
Jean L, Tan, Yan Z, Tan, Ruth, Muljadi, Siow T, Chan, Sin N, Lau, Joanne C, Mockler, Euan M, Wallace, Rebecca, Lim
Publikováno v:
Stem Cells Translational Medicine
Human amnion epithelial cells (hAECs) have been shown to possess potent immunomodulatory properties across a number of disease models. Recently, we reported that hAECs influence macrophage polarization and activity, and that this step was dependent o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7ffbdb7eae75384aea6cf63d22c6e2e0
https://pubmed.ncbi.nlm.nih.gov/28371562
https://pubmed.ncbi.nlm.nih.gov/28371562