Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jean Geneve"'
Autor:
Jean Genève Schubert
Si la théorie est en place, la pratique est loin d'être une certitude. « La théorie c'est quand on sait tout, mais rien ne fonctionne. La pratique c'est quand tout fonctionne, mais personne ne sait pourquoi. La théorie et la pratique réunies,
Publikováno v:
Journal of hepatology. 11(2)
A case of primary sclerosing cholangitis associated with cystic dilatations of intrahepatic bile ducts simulating Caroli's disease is described. The diagnosis of primary sclerosing cholangitis was based upon cholangiogram features, liver histologic e
Autor:
Dominique Pessayre, Marina Tinel, Veronique Descatoire, Jacques Belghiti, Jean Geneve, Dominique Larrey, Philippe Lettéron, Gilles Amouyal
Publikováno v:
Biochemical Pharmacology. 36:951-955
The effects of psoralen derivatives on cytochrome P-450 have been studied in human liver microsomes. CO-binding cytochrome P-450 was decreased by 33% after 10 min of incubation with 1.5 mM EDTA, an NADPH-regenerating system and 20 microM methoxsalen
Publikováno v:
Journal of Hepatology. 9:130-133
Autor:
Gilles Amouyal, Dominique Larrey, Jean Geneve, Dominique Pessayre, Marina Tinel, Veronique Descatoire, Philippe Lettéron
Publikováno v:
Biochemical Pharmacology. 36:323-329
Incubation of [ 14 C] amineptine (1 mM) with hamster liver microsomes resulted in the irreversible binding of an amineptine metabolite to microsomal proteins. Covalent binding measured in the presence of various concentrations of amineptine (0.0625-1
Autor:
Dominique Larrey, Gilles Amouyal, Philippe Lettéron, Dominique Pessayre, Claude Degott, Jean Geneve, Veronique Descatoire, Marina Tinel
Publikováno v:
Biochemical Pharmacology. 36:331-337
Incubation of [11- 14 C]aimneptine (1 mM) with an NADPH-generaung system and hamster liver microsomes resulted in the in vitro covalent binding of an amineptine metabolite to microsomal proteins; this binding was decreased by 41–71% in the presence
Autor:
Dominique Pessayre, Marina Tinel, Veronique Descatoire, Jean Geneve, Dominique Larrey, Philippe Lettéron
Publikováno v:
Biochemical Pharmacology. 35:2213-2220
Administration of amiodarone hydrochloride (50-150 mg/kg i.p. daily) to rats, mice or hamsters resulted in the in vivo formation of a cytochrome P-450Fe(II)-amiodarone metabolite complex absorbing at 453 nm, unable to bind CO and biologically inactiv
Autor:
Jean Geneve, Claude Degott, Dominique Pessayre, Jean-pierre Machayekhi, Dominique Larrey, Jean-Pierre Benhamou
Publikováno v:
Journal of Clinical Gastroenterology. 9:102-104
We report a patient in whom cyproheptadine-induced hepatitis was followed by prolonged cholestasis marked by elevation of serum alkaline phosphatase levels, gammaglut-amyltransferase and bile acid levels, and disappearance of small bile ducts. Chlorp
Publikováno v:
Biochemical pharmacology. 36(14)
Autor:
Marina Tinel, Yasna Carrion-Pavlov, Gilles Amouyal, Dominique Pessayre, Philippe Lettéron, Claude Degott, Dominique Larrey, Jean Geneve, Gilles Labbe, Veronique Descatoire
Publikováno v:
Biochemical pharmacology. 36(6)
Methoxsalen, a potent suicide inhibitor of cytochrome P-450 that can be used in humans, might be of value for the prevention of hepatitis in subjects with carbon tetrachloride poisoning. As a preliminary step, we have determined its effects on the he