Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jean Francois Hernandez"'
Autor:
Arpita Dey, Ran Chen, Feng Li, Subhamita Maitra, Jean-Francois Hernandez, Guo-Chun Zhou, Bruno Vincent
Publikováno v:
Molecules, Vol 26, Iss 24, p 7660 (2021)
Alzheimer’s disease (AD) is a devastating neurodegenerative disorder, one of the main characteristics of which is the abnormal accumulation of amyloid peptide (Aβ) in the brain. Whereas β-secretase supports Aβ formation along the amyloidogenic p
Externí odkaz:
https://doaj.org/article/c68621c20a804985b61232ddfe1cd0b5
Autor:
Mehbuba Nur Protha, Therathep Srisutjarit, Arpita Dey, Subhamita Maitra, Jean-Francois Hernandez, Mayuree H. Tantisira, Yingrak Boondam, Narawut Pakaprot, Bruno Vincent
Publikováno v:
ScienceAsia. 49:256
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10de0d44e51ba77e0e669f8c66be866e
https://doi.org/10.2306/scienceasia1513-1874.2023.014
https://doi.org/10.2306/scienceasia1513-1874.2023.014
Autor:
Antonio Miranda, Wayne Kornreich, Gayle Yamamoto, Wylie Vale, Jean Francois Hernandez, Catherine Rivier, Yvette Taché, John S. Andrews, Jean Rivier
Publikováno v:
Journal of Medicinal Chemistry. 36:2860-2867
Two series of CRF antagonists with N alpha- and C alpha-methylated alanine and leucines were evaluated for their biological activities in vitro and in vivo in several systems. The poly-N-methylated analogue of alpha-helical-CRF9-41, [N alpha MeLeu10,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::733154240f12438e1720e47d7a596ef8
https://doi.org/10.1021/jm00072a004
https://doi.org/10.1021/jm00072a004
Publikováno v:
Analytica Chimica Acta. 249:215-225
Synthetic peptides (up to 40 residues in length) are routinely purified and characterized by reversed-phase liquid chromatography (RP-LC). However, as the peptide size is further increased, this technique becomes less efficient in separating micro-he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c78f2623b9519c18339b991d0340a2dc
https://doi.org/10.1016/0003-2670(91)87025-3
https://doi.org/10.1016/0003-2670(91)87025-3
Autor:
Lourdes J. Cruz, J. Michael McIntosh, Jean Rivier, Terry Oas, Richard A. Myers, Jean Francois Hernandez, Robert W. Williams, Baldomero M. Olivera, Julie A. Haack, Julita S. Imperial
Publikováno v:
Journal of Toxicology: Toxin Reviews. 9:179-202
The venoms of fish-hunting Conus contain paralytic conotoxins and an unprecedented variety of other biologically-active peptides. Particularly noteworthy are peptides which inhibit calcium entry into neurons, the conantokins and w-conotoxins which ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::396d50cbe8dbfdb144ef231756f57b66
https://doi.org/10.3109/15569549009033113
https://doi.org/10.3109/15569549009033113
Autor:
Petit-Paitel, Agnès, Frederic, Checler, Cristine, Alves, Erwan, Ayral, David, Andrau, Cecile, Dumanchin, Michael, Farzan, Jean-Francois, Hernandez, Martinez, J., Solveig, Lefranc-Jullien, Philippe, Marambaud, Andrea, Pasini, Agnes, Petit, Christopher, Phiel, Philippe, Robert, St George-Hyslop Peter, Bentham Science Publisher, Sherwin, Wilk
Publikováno v:
Current Alzheimer Research
Current Alzheimer Research, Bentham Science Publishers, 2005, 2 (3), pp.327-334. ⟨10.2174/1567205054367874⟩
Current Alzheimer Research, Bentham Science Publishers, 2005, 2 (3), pp.327-334. ⟨10.2174/1567205054367874⟩
Alzheimers disease is characterized by the extracellular deposition of the amyloid β-peptide that derives from its precursor bAPP by sequential actions of β- and γ- secretases, respectively. Recent studies aimed at identifying these enzymes have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80486c80d2211c214e0f380f474ce69d
https://hal.archives-ouvertes.fr/hal-03016641
https://hal.archives-ouvertes.fr/hal-03016641
Autor:
David, Andrau, Cecile, Dumanchin-Njock, Erwan, Ayral, Jean, Vizzavona, Mike, Farzan, Michel, Boisbrun, Pierre, Fulcrand, Jean-Francois, Hernandez, Jean, Martinez, Solveig, Lefranc-Jullien, Frederic, Checler
Publikováno v:
The Journal of biological chemistry. 278(28)
We have set up stably transfected HEK293 cells overexpressing the beta-secretases BACE1 and BACE2 either alone or in combination with wild-type beta-amyloid precursor protein (betaAPP). The characterization of the betaAPP-derived catabolites indicate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::25bfaf75629d9531b2ec394720a5f3b2
https://pubmed.ncbi.nlm.nih.gov/12736275
https://pubmed.ncbi.nlm.nih.gov/12736275
Autor:
Jean Francois Hernandez, Catherine Rivier, Gayle Yamamoto, Wayne Kornreich, Cynthia J. Donaldson, A. G. Craig, Jean Rivier, R. Galyean, Wylie Vale
Publikováno v:
Journal of medicinal chemistry. 35(10)
Previous structure-activity relationship studies of CRF have shown that residues 1-4 were not necessary for receptor binding or transduction, that residues 4-8 were important for activation, and that residues 12-41 were mostly responsible for binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::207b4c1e774cc18cc11eb681deac6894
https://pubmed.ncbi.nlm.nih.gov/1316969
https://pubmed.ncbi.nlm.nih.gov/1316969
Autor:
Frederic, Checler, Cristine, Alves da Costa, Erwan, Ayral, David, Andrau, Cecile, Dumanchin, Michael, Farzan, Jean-Francois, Hernandez, Martinez, J., Solveig, Lefranc-Jullien, Philippe, Marambaud, Andrea, Pasini, Agnes, Petit, Christopher, Phiel, Philippe, Robert, Peter, St George-Hyslop, Sherwin, Wilk
Publikováno v:
Current Alzheimer Research; July 2005, Vol. 2 Issue: 3 p327-334, 8p