Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Jean François Dumas"'
Autor:
Alison Robert, David Crottès, Jérôme Bourgeais, Naig Gueguen, Arnaud Chevrollier, Jean-François Dumas, Stéphane Servais, Isabelle Domingo, Stéphanie Chadet, Julien Sobilo, Olivier Hérault, Thierry Lecomte, Christophe Vandier, William Raoul, Maxime Guéguinou
Publikováno v:
PLoS Biology, Vol 22, Iss 10, p e3002854 (2024)
The mitochondrial Ca2+ uniporter (MCU) plays crucial role in intramitochondrial Ca2+ uptake, allowing Ca2+-dependent activation of oxidative metabolism. In recent decades, the role of MCU pore-forming proteins has been highlighted in cancer. However,
Externí odkaz:
https://doaj.org/article/d921cf1a11eb48efbb81622c970372c0
Autor:
Adeline Dolly, Thierry Lecomte, Nicolas Tabchouri, Morgane Caulet, Nicolas Michot, Benjamin Anon, Romain Chautard, Yoann Desvignes, Mehdi Ouaissi, Gaëlle Fromont‐Hankard, Jean‐François Dumas, Stéphane Servais
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 3, Pp 1837-1849 (2022)
Abstract Background Cancer cachexia is a multifactorial syndrome characterized by involuntary and pathological weight loss, mainly due to skeletal muscle wasting, resulting in a decrease in patients' quality of life, response to cancer treatments, an
Externí odkaz:
https://doaj.org/article/6a68b874a41c439bb8a225535c7618c3
Autor:
Olivier L. Mantha, Régis Hankard, Illa Tea, Anne-Marie Schiphorst, Jean-François Dumas, Virginie Berger, Caroline Goupille, Philippe Bougnoux, Arnaud De Luca
Publikováno v:
Metabolites, Vol 12, Iss 10, p 899 (2022)
While clinical evidence remains limited, an extensive amount of research suggests a beneficial role of n-3 polyunsaturated fatty acid supplementation in cancer treatment. One potential benefit is an improvement of protein homeostasis, but how protein
Externí odkaz:
https://doaj.org/article/5a51e8a0d8384f06827cdd55c3a3d01e
Autor:
Charlotte Orre, Xavier Dieu, Jordan Guillon, Naïg Gueguen, Seyedeh Tayebeh Ahmadpour, Jean-François Dumas, Salim Khiati, Pascal Reynier, Guy Lenaers, Olivier Coqueret, Arnaud Chevrollier, Delphine Mirebeau-Prunier, Valérie Desquiret-Dumas
Publikováno v:
Biology, Vol 10, Iss 11, p 1156 (2021)
Despite improvements in therapeutic strategies for treating breast cancers, tumor relapse and chemoresistance remain major issues in patient outcomes. Indeed, cancer cells display a metabolic plasticity allowing a quick adaptation to the tumoral micr
Externí odkaz:
https://doaj.org/article/98353807760346749bdef56025f7443a
Autor:
Marion Seillier, Laurent Pouyet, Prudence N'Guessan, Marie Nollet, Florence Capo, Fabienne Guillaumond, Laure Peyta, Jean‐François Dumas, Annie Varrault, Gyslaine Bertrand, Stéphanie Bonnafous, Albert Tran, Gargi Meur, Piero Marchetti, Magalie A Ravier, Stéphane Dalle, Philippe Gual, Dany Muller, Guy A Rutter, Stéphane Servais, Juan L Iovanna, Alice Carrier
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 6, Pp 802-818 (2015)
Abstract The metabolic syndrome covers metabolic abnormalities including obesity and type 2 diabetes (T2D). T2D is characterized by insulin resistance resulting from both environmental and genetic factors. A genome‐wide association study (GWAS) pub
Externí odkaz:
https://doaj.org/article/a391b04c6a3242c3a64fb5dbffab3422
Autor:
Luca, Olivier L. Mantha, Régis Hankard, Illa Tea, Anne-Marie Schiphorst, Jean-François Dumas, Virginie Berger, Caroline Goupille, Philippe Bougnoux, Arnaud De
Publikováno v:
Metabolites; Volume 12; Issue 10; Pages: 899
While clinical evidence remains limited, an extensive amount of research suggests a beneficial role of n-3 polyunsaturated fatty acid supplementation in cancer treatment. One potential benefit is an improvement of protein homeostasis, but how protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::21d85b411c88645533e532d3707baf9e
Autor:
Maxime Guéguinou, Sajida Ibrahim, Jérôme Bourgeais, Alison Robert, Trayambak Pathak, Xuexin Zhang, David Crottès, Jacques Dupuy, David Ternant, Valérie Monbet, Roseline Guibon, Hector Flores-Romero, Antoine Lefèvre, Stéphanie Lerondel, Alain Le Pape, Jean-François Dumas, Philippe G. Frank, Alban Girault, Romain Chautard, Françoise Guéraud, Ana J. García-Sáez, Mehdi Ouaissi, Patrick Emond, Olivier Sire, Olivier Hérault, Gaëlle Fromont-Hankard, Christophe Vandier, David Tougeron, Mohamed Trebak, William Raoul, Thierry Lecomte
Publikováno v:
Cellular and Molecular Life Sciences
Cellular and Molecular Life Sciences, 2022, 79 (6), pp.article n° 284. ⟨10.1007/s00018-022-04311-4⟩
Cellular and Molecular Life Sciences, 2022, 79 (6), pp.article n° 284. ⟨10.1007/s00018-022-04311-4⟩
Colorectal cancer (CRC) is associated with high mortality worldwide and new targets are needed to overcome treatment resistance. Recent evidences highlight a role of the mitochondria calcium homeostasis in the development of CRC. In this context, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bfb4da2eb5ac132771be349515dc220
https://doi.org/10.1007/s00018-022-04311-4
https://doi.org/10.1007/s00018-022-04311-4
Autor:
Jean-François Dumas, Lucie Brisson
Publikováno v:
Cancer and Metastasis Reviews
Cancer and Metastasis Reviews, 2020, ⟨10.1007/s10555-020-09934-2⟩
Cancer and Metastasis Reviews, Springer Verlag, 2020, ⟨10.1007/s10555-020-09934-2⟩
Cancer and Metastasis Reviews, 2020, ⟨10.1007/s10555-020-09934-2⟩
Cancer and Metastasis Reviews, Springer Verlag, 2020, ⟨10.1007/s10555-020-09934-2⟩
Environment surrounding tumours are now recognized to play an important role in tumour development and progression. Among the cells found in the tumour environment, adipocytes from adipose tissue establish a vicious cycle with cancer cells to promote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fb8d010e6ee04a4bc94ffdbc8d97b13
https://doi.org/10.1007/s10555-020-09934-2
https://doi.org/10.1007/s10555-020-09934-2
Autor:
Helene Salaun, Mathilde Poisson, Adeline Dolly, Flavie Arbion, Stéphane Servais, Jean François Dumas, Caroline Goupille, Lobna Ouldamer
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 2; Pages: 1768
Prognostic factors for epithelial ovarian cancers (EOCs) are in particular clinical factors such as pathology staging at diagnosis (FIGO stages), genetic mutation, or histological phenotypes. In the present study, FIGO stage, tumor residue after surg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b745e29842c0ac3f18022867daa6e46a
https://doi.org/10.3390/ijms24021768
https://doi.org/10.3390/ijms24021768
Autor:
Philippe Bougnoux, Jean-François Dumas, Olivier L Mantha, Caroline Goupille, Arnaud De Luca, Richard Robins, Régis Hankard
Publikováno v:
American Journal of Clinical Nutrition
American Journal of Clinical Nutrition, American Society for Nutrition, 2020, 111 (5), pp.1109-1110. ⟨10.1093/ajcn/nqaa053⟩
Am J Clin Nutr
American Journal of Clinical Nutrition, American Society for Nutrition, 2020, 111 (5), pp.1109-1110. ⟨10.1093/ajcn/nqaa053⟩
Am J Clin Nutr
International audience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bf1757dcae8a2cf46e93d7fd397d1b5
https://hal.archives-ouvertes.fr/hal-02975424
https://hal.archives-ouvertes.fr/hal-02975424
