Zobrazeno 1 - 10
of 264
pro vyhledávání: '"Jean François Constant"'
Publikováno v:
History and Theory, 2010 May 01. 49(2), 311-311.
Externí odkaz:
https://www.jstor.org/stable/40864451
In 2000, Ian McKay, a highly respected historian at Queen's University, published an article in the Canadian Historical Review entitled'The Liberal Order Framework: A Prospectus for a Reconnaissance of Canadian History.'Written to address a crisis in
Autor:
Christian Roy
Publikováno v:
Recherches sociographiques. 53:693
Autor:
Frédéric Boily
Publikováno v:
Mens: Revue d'histoire intellectuelle de l'Amérique française. 11:103
Publikováno v:
AIMS Materials Science, Vol 2, Iss 4, Pp 473-483 (2015)
Ionizing radiations induce clustered damage sites known to be severely challenging for the cell's repair machinery. In the present study, we have grafted on a biochip four synthetic oligonucleotide duplexes containing either a single 8-oxoguanine, a
Externí odkaz:
https://doaj.org/article/97d7bb012ab142a59267099df63e5c2a
Publikováno v:
Biochemistry
Biochemistry, American Chemical Society, 2016, 55 (28), pp.3899-3906. ⟨10.1021/acs.biochem.6b00396⟩
Biochemistry, American Chemical Society, 2016, 55 (28), pp.3899-3906. ⟨10.1021/acs.biochem.6b00396⟩
Ionizing radiation, free radicals, and reactive oxygen species produce hundreds of different DNA lesions. Clustered lesions are typical for ionizing radiation. They compromise the efficiency of the base excision repair (BER) pathway, and as a consequ
Publikováno v:
AIMS Materials Science, Vol 2, Iss 4, Pp 473-483 (2015)
AIMS Materials Science
AIMS Materials Science, AIMS Press, 2015, 2 (4), pp.473-483. ⟨10.3934/matersci.2015.4.473⟩
AIMS Materials Science, 2015, 2 (4), pp.473-483. ⟨10.3934/matersci.2015.4.473⟩
AIMS Materials Science
AIMS Materials Science, AIMS Press, 2015, 2 (4), pp.473-483. ⟨10.3934/matersci.2015.4.473⟩
AIMS Materials Science, 2015, 2 (4), pp.473-483. ⟨10.3934/matersci.2015.4.473⟩
Ionizing radiations induce clustered damage sites known to be severely challenging for the cell's repair machinery. In the present study, we have grafted on a biochip four synthetic oligonucleotide duplexes containing either a single 8-oxoguanine, a
Publikováno v:
Journal of Molecular Biology
Journal of Molecular Biology, Elsevier, 2014, 426 (7), pp.1524-1538. ⟨10.1016/j.jmb.2013.12.022⟩
Journal of Molecular Biology, Elsevier, 2014, 426 (7), pp.1524-1538. ⟨10.1016/j.jmb.2013.12.022⟩
International audience; Clustered DNA damage sites are caused by ionizing radiation. They are much more difficult to repair than are isolated single lesions, and their biological outcomes in terms of mutagenesis and repair inhibition are strongly dep
Autor:
Rémy Lartia, Jean-François Constant
Publikováno v:
Journal of Organic Chemistry
Journal of Organic Chemistry, American Chemical Society, 2015, 80 (2), pp.705-710. ⟨10.1021/jo502170e⟩
Journal of Organic Chemistry, American Chemical Society, 2015, 80 (2), pp.705-710. ⟨10.1021/jo502170e⟩
Hydrogen atom abstraction from the C5′-position of nucleotides in DNA results in direct strand scission by generating alkali-labile fragments from the oxidized nucleotide. The major damage consists in a terminus containing a 5′-aldehyde as part o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357168f780f4ceae713e0161464d9ac7
https://hal.archives-ouvertes.fr/hal-01651416
https://hal.archives-ouvertes.fr/hal-01651416
Autor:
Olivier Lentzen, Stephan Schumm, Eric Defrancq, Jean-François Constant, Cécile Moucheron, Andrée Kirsch-De Mesmaeker, David García-Fresnadillo, Pascal Dumy
Publikováno v:
JBIC Journal of Biological Inorganic Chemistry. 9:100-108
The influence of the distance between the an- choring site of the tethered (Ru(TAP)2dip) 2+ complex (TAP=1,4,5,8-tetraazaphenanthrene; dip=4,7-diphe- nyl-1,10-phenanthroline) on a probe sequence and the guanines of the complementary target strand was