Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Jean François, Pujol"'
Autor:
Gaëlle Pinto Cardoso, Marion Lagrée-Chastan, Marion Caseris, Joël Gaudelus, Hervé Haas, Jean-Philippe Leroy, Pierre Bakhache, Jean-François Pujol, Andreas Werner, Marie-Aliette Dommergues, Emilie Pauquet, Didier Pinquier
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
BackgroundIn Europe, meningococcal (Men) vaccines are available against 5 of the 6 serogroups responsible of nearly all cases of invasive meningococcal disease (IMD). Meningococcal vaccination has been introduced in the national immunization programs
Externí odkaz:
https://doaj.org/article/4429fa442a354fed988155eda9ac72f2
Autor:
Nicolas Salvetat, Fabrice Chimienti, Christopher Cayzac, Benjamin Dubuc, Francisco Checa-Robles, Pierrick Dupre, Sandie Mereuze, Vipul Patel, Catherine Genty, Jean-Philippe Lang, Jean-François Pujol, Philippe Courtet, Dinah Weissmann
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Mental health issues, including major depressive disorder, which can lead to suicidal behavior, are considered by the World Health Organization as a major threat to global health. Alterations in neurotransmitter signaling, e.g., serotonin an
Externí odkaz:
https://doaj.org/article/bca99aa3dff34829b47596cc87a00f80
Autor:
Laurent Vincent, Dinah Weissmann, Nicolas Salvetat, Eve Mathieu-Dupas, Frédéric Allemand, Claudia Le Borgne, Franck Molina, Laurent Cavarec, Camille Plusquellec, Priscilla Normandie-Levi, Jean-François Pujol, Nathalie Ollivier
Publikováno v:
Neurotoxicity Research. 23:49-62
Many drugs in clinical trials, or already on the market, can have psychiatric side effects, independently of their therapeutic indication (e.g., Acomplia, Taranabant, and Roaccutane). There is currently no in vitro or in vivo approved test for the de
Autor:
Jean-Jacques Madjar, Herve Berthomme, Catherine Paul, Brigitte Nicolas, Jean-François Pujol, Alain Poyau, Laurent Vincent
Publikováno v:
ELECTROPHORESIS. 28:2843-2852
A new method has been developed allowing the identification and relative quantification of different forms of mRNA after RNA editing. This method was applied to the serotonin 2c receptor mRNA that potentially exhibits 32 different forms after adenosi
Autor:
Jérôme Redouté, Maguelone G. Forest, Luc Cinotti, Henri Déchaud, Didier Le Bars, Michel Pugeat, F. Lavenne, Jean François Pujol, Nicolas Costes, Serge Stoléru
Publikováno v:
Psychiatry Research: Neuroimaging. 124:67-86
Although hypoactive sexual desire disorder (HSDD) is a common condition and has long been hypothesized to result from malfunctions of the cerebral control mechanisms that adjust the level of sexual motivation, very little is known about the pathophys
Autor:
André Luxen, Nicolas Costes, Luc Cinotti, Jean-François Pujol, Jacques Delforge, Luc Zimmer, Didier Le Bars, Isabelle Merlet, Franck Lavenne
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 22:753-765
The selectivity of [18F]MPPF (fluorine-18-labeled 4-(2' -methoxyphenyl)-1-[2' -(N-2“-pirydynyl)-p-fluorobenzamido]ethylpiperazine) for serotonergic 5-hydroxytryptamine(1A) (5-HT1A) receptors has been established in animals and humans. The authors q
Autor:
André Luxen, Jean-François Pujol, Abdallah Gharib, Nicole Sarda, Alain Plenevaux, Cédar Balende, Pierre Bobillier, Dinah Weissmann
Publikováno v:
Journal of Neurochemistry. 72:2593-2600
Biochemical approaches were used in freely moving rats to determine, under steady-state conditions, the brain/arterial plasma partition coefficients of L-tryptophan and alpha-[3H]methyl-L-tryptophan, from which the lumped constant for the alpha-methy
Autor:
C. Brihaye, Dominique Comar, A Plenevaux, André Luxen, Jean-François Pujol, Dinah Weissmann, Christian Degueldre, Christian Lemaire, D. Le Bars, J. Aerts
Publikováno v:
Journal of Neurochemistry. 75:803-811
The in vivo behavior of 4-(2'-methoxyphenyl)-1-[2'-[N-(2"-pyridinyl)-p-[(18)F]fluorobenzamido ]ethyl]-piperazine (p-[(18)F]MPPF), a new serotonin 5-HT(1A) antagonist, was studied in awake, freely moving rats. Biodistribution studies showed that the c
Publikováno v:
Neurochemical Research. 27:269-275
Changes in tissue and extracellular serotonin (5-HT) in raphe dorsalis, raphe medialis and in their main projections areas (hippocampus, striatum and frontal cortex) were investigated at short and long-term times after single injection (5 mg/kg ip) o
Autor:
P. Laniece, Frédéric Pain, Vincent Leviel, L. Valentin, R. Mastrippolito, Jean-François Pujol, Y. Charon, Dominique Comar
Publikováno v:
IEEE Transactions on Nuclear Science. 47:25-32
Although high-resolution tomographs provide a new approach that strongly simplifies the measurement of in vivo tracer biodistribution and kinetics in small animals, they suffer from an important drawback: the need for animal anesthesia or immobilizat