Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jean F. Ruiz-Calderon"'
Autor:
Suranganie Dharmawardhane, Cornelis P. Vlaar, Eliud Hernández-O'Farrill, Marvin J. Bayro, Julia I. Medina, Jorge Duconge, Maria del Mar Maldonado, Linette Castillo-Pichardo, Irmaris Lopez, Luis D. Borrero-Garcia, Hector Picon, Jean F. Ruiz-Calderon, Ailed Cruz-Collazo
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::522138c1ae203a4ce68bbba6c1c27101
https://doi.org/10.1158/1535-7163.22522143.v1
https://doi.org/10.1158/1535-7163.22522143.v1
Autor:
Suranganie Dharmawardhane, Cornelis P. Vlaar, Eliud Hernández-O'Farrill, Marvin J. Bayro, Julia I. Medina, Jorge Duconge, Maria del Mar Maldonado, Linette Castillo-Pichardo, Irmaris Lopez, Luis D. Borrero-Garcia, Hector Picon, Jean F. Ruiz-Calderon, Ailed Cruz-Collazo
Triple-negative breast cancer (TNBC) is an aggressive form of breast cancer, with a high predisposition for locally invasive and metastatic cancer. With the objective to reduce cancer metastasis, we developed small molecule inhibitors to target the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44c9aa603e121d9e466d2d54a0548109
https://doi.org/10.1158/1535-7163.c.6543291.v1
https://doi.org/10.1158/1535-7163.c.6543291.v1
Autor:
Julia I. Medina, Linette Castillo-Pichardo, Maria Del Mar Maldonado, Ailed Cruz-Collazo, Suranganie Dharmawardhane, Cornelis P. Vlaar, Jean F. Ruiz-Calderon, Eliud Hernandez-O'Farrill, Luis D. Borrero-Garcia, Jorge Duconge, Marvin J Bayro, Irmaris Lopez, Hector M. Picon
Publikováno v:
Mol Cancer Ther
Triple-negative breast cancer (TNBC) is an aggressive form of breast cancer, with a high predisposition for locally invasive and metastatic cancer. With the objective to reduce cancer metastasis, we developed small molecule inhibitors to target the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b8a786a81c08334bd6c435b9965a5b0
https://europepmc.org/articles/PMC8643341/
https://europepmc.org/articles/PMC8643341/
Autor:
Clarisse Marotz, Wesley K. Thompson, Nora Henderson, William Schweizer, Elizabeth Ackley, Jincheng Wang, Maribel Campos-Rivera, Valentina Montacuti, Deanna Nardella, Cameron Martino, Lingjing Jiang, Juana I Rivera-Viñas, Se Jin Song, Jean F. Ruiz-Calderon, Melanie Jay, Rob Knight, Joan Combellick, Maria Gloria Dominguez-Bello, Daniel McDonald, Izaskun García-Mantrana, Fernando Gil Raga, Maria Carmen Collado, Caroll Hernández, Haipeng Sun, Charles Gillihan, Paul R. Harris, Liat Shenhav
Publikováno v:
Med (New York, N.Y.), vol 2, iss 8
Med (N Y)
Med (N Y)
Early microbiota perturbations are associated with disorders that involve immunological underpinnings. Cesarean section (CS)-born babies show altered microbiota development in relation to babies born vaginally. Here we present the first statistically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::320d146b2817f06554d26ed4486ca6d1
https://escholarship.org/uc/item/9d15k1pk
https://escholarship.org/uc/item/9d15k1pk
Autor:
Chris Callewaert, Laura-Isobel McCall, Henrique dos Santos Pereira, Martin J. Blaser, Jeremiah J. Minich, Madeleine Ernst, Ora Lee H. Branch, Rob Knight, Amina Bouslimani, Qiyun Zhu, Jean N. Hernandez, Humberto Cavallin, Pieter C. Dorrestein, Luciana C. Paulino, Atila Novoselac, Maria Gloria Dominguez-Bello, Jean F. Ruiz-Calderon, Rafael Rios, Se Jin Song
Publikováno v:
Nature microbiology
Urbanization represents a profound shift in human behaviour, and has considerable cultural and health-associated consequences1,2. Here, we investigate chemical and microbial characteristics of houses and their human occupants across an urbanization g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::624320ac7a50c2ee18facbc474bfc7d4
https://doi.org/10.1038/s41564-019-0593-4
https://doi.org/10.1038/s41564-019-0593-4
Autor:
José F. Rodríguez-Orengo, Maria Del Mar Maldonado, Gabriela Rosado-González, Eliud Hernandez-O'Farrill, Cornelis P. Vlaar, Jorge Duconge, Suranganie Dharmawardhane, Jean F. Ruiz-Calderon, Joseph Bloom
Publikováno v:
ACS Omega, Vol 4, Iss 19, Pp 17981-17989 (2019)
ACS Omega
ACS Omega
The Rho GTPases Rac and Cdc42 are potential targets against metastatic diseases. We characterized the small molecule MBQ-167 as an effective dual Rac/Cdc42 inhibitor that reduces HER2-type tumor growth and metastasis in mice by ∼90%. This study rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ec2e92d21a7adcf7661fd5580a92404
https://doaj.org/article/372433e0c63343658e826b365e127300
https://doaj.org/article/372433e0c63343658e826b365e127300
Autor:
Surangani Dharmawardhane, JI Medina-Vlazquez, Linette Castillo-Pichardo, Pablo E. Vivas-Mejia, Jean F. Ruiz-Calderon, LE Velazquez-Vega, Michael John Rivera-Robles, Luis Borrero-Garcia, MdM Maldonado
Publikováno v:
Cancer Research. 79:P6-21
Breast cancer metastasis, when cancer cells move and establish tumors in distant organs, confounds treatment options. Therefore, there is an unmet need for targeted therapeutics to address metastasis, especially in the intractable HER2 positive (+) b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57f68e58e0398e5b6bc9946be7a89619
https://doi.org/10.1158/1538-7445.sabcs18-p6-21-14
https://doi.org/10.1158/1538-7445.sabcs18-p6-21-14
Autor:
Jean F. Ruiz-Calderon, Jorge Duconge, Suranganie Dharmawardhane, Ailed M. Cruz-Collazo, Maria Del Mar Maldonado, Gabriela Tatiana Rosado-González, Luis D. Borrero-Garcia
Publikováno v:
Cancer Research. 80:3020-3020
The Rho GTPases Rac and Cdc42 are potential targets against metastatic disease. Our group characterized the small molecule MBQ-167 as an effective dual Rac/Cdc42 inhibitor that reduces HER2 positive and triple negative tumor growth and metastasis in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c750a6230b6257c5483885fa714e664
https://doi.org/10.1158/1538-7445.am2020-3020
https://doi.org/10.1158/1538-7445.am2020-3020
Publikováno v:
Clinical Cancer Research. 26:17-17
Triple-negative breast cancer (TNBC) is an aggressive form of breast cancer, with a high predisposition for locally advanced and metastatic cancer. While targeted therapies for TNBC are in various stages of development, current standard chemotherapie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fe88554457529f5755377c16151fde4
https://doi.org/10.1158/1557-3265.advprecmed20-17
https://doi.org/10.1158/1557-3265.advprecmed20-17
Autor:
Jean F. Ruiz-Calderon, Maria Gloria Dominguez-Bello, María Pagán-Jiménez, José E. García-Arrarás
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 1, p e0208011 (2019)
PLoS ONE, Vol 14, Iss 1, p e0208011 (2019)
High-throughput 16S rRNA gene sequencing has been used to identify the intestinal microbiota of many animal species, but that of marine invertebrate organisms remains largely unknown. There are only a few high-throughput sequencing studies on the int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::708d5d8ce4834eec2f12636d4f0e192e
https://pubmed.ncbi.nlm.nih.gov/30699110
https://pubmed.ncbi.nlm.nih.gov/30699110