Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jean F. Gardin"'
Publikováno v:
Toxicologic Pathology. 50:574-590
Laboratory animal research is an important contributor to both human and animal medicine. Currently, there is extensive use of cynomolgus monkeys ( Macaca fascicularis) in pathology and toxicology research. The purpose of this study was to define ref
Publikováno v:
Toxicol Pathol
Laboratory animal research is an important contributor to both human and animal medicine. Currently, there is extensive use of cynomolgus monkeys (Macaca fascicularis) in pathology and toxicology research. The purpose of this study was to define refe
Publikováno v:
Journal of Bone and Mineral Research. 11:1209-1217
Knee joints from cynomolgus monkeys of both genders and a wide range of ages were examined to characterize further the natural history of osteoarthritis (OA) in these animals. The objectives of this study were to characterize better the subchondral b
Publikováno v:
Journal of Orthopaedic Research. 20:92-100
The purposes of this study were to document the histological changes present in the tibial plateaus 12 weeks after complete medial meniscectomy in dogs and to determine if synovial lavage fluid biomarker levels are predictive of the severity of joint
Autor:
Cathy S. Carlson, Jean F. Gardin, Brent J. Shelton, Gouri Shanker, Richard F. Loeser, William E. Sonntag
Publikováno v:
Arthritis & Rheumatism. 43:2110-2120
Objective Although the development of osteoarthritis (OA) is closely associated with aging, the mechanism for this association is not clear. This study was designed to determine the effects of aging and OA on the chondrocyte response to stimulation w
Autor:
Stephen J. Delatte, Theodore Feely, Jean F. Gardin, Robert J. Kreitman, Philip D. Hall, Amy Latimer, Edward P. Tagge, Mark C. Willingham, Arthur E. Frankel, J. Mark Cline, J. Ramage, Charlotte E. Hotchkiss
Publikováno v:
Toxicology and Applied Pharmacology. 158:152-160
We developed a fusion toxin consisting of the catalytic and translocation domains of diphtheria toxin linked to human granulocyte-macrophage colony-stimulating factor (GM-CSF) (DTGM) for the treatment of patients with acute myeloid leukemia (AML). Ou