Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Jean F, Regal"'
Autor:
Tracy K. Her, Jin Li, Hao Lin, Dong Liu, Kate M. Root, Jean F. Regal, Emilyn U. Alejandro, Ruifeng Cao
Publikováno v:
Metabolites, Vol 14, Iss 2, p 126 (2024)
Circadian rhythm disruption is associated with impaired glucose homeostasis and type 2 diabetes. For example, night shift work is associated with an increased risk of gestational diabetes. However, the effects of chronic circadian disruption since ea
Externí odkaz:
https://doaj.org/article/207548a9a9a24260887e01b423551431
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/4d8f7a47c01546e584b72107d6afe10f
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The complement cascade was identified over 100 years ago, yet investigation of its role in pregnancy remains an area of intense research. Complement inhibitors at the maternal-fetal interface prevent inappropriate complement activation to protect the
Externí odkaz:
https://doaj.org/article/266fd5a141724f06a3000c968ddcaecd
Autor:
Connor F. Laule, Cameron R. Wing, Evan J. Odean, Jacob A. Wilcox, Jeffrey S. Gilbert, Jean F. Regal
Publikováno v:
Journal of Immunotoxicology, Vol 14, Iss 1, Pp 235-240 (2017)
Preeclampsia is a pregnancy-specific condition manifested by new-onset maternal hypertension with systemic inflammation, including increased innate immune system complement activation. While exact pathophysiology is unknown, evidence suggests that in
Externí odkaz:
https://doaj.org/article/7d2f0ada378d46308c646fbef8f641a0
Autor:
Jean F. Regal, Emilyn U. Alejandro, Ronald R. Regal, Connor F. Laule, Margaretta E. Huchthausen, Alexa M. Molin, Melissa A. Cedars, Brian Akhaphong, Kate M. Root
Preeclampsia is a pregnancy-specific complication with long-term negative outcomes for offspring including increased susceptibility to type 2 diabetes (T2D) in adulthood. In rat Reduced Uteroplacental Perfusion Pressure (RUPP) model of chronic placen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3238ed3ca746b1d4a7a81813d483c6ef
https://doi.org/10.2337/figshare.20995165.v1
https://doi.org/10.2337/figshare.20995165.v1
Autor:
Jean F Regal, Melissa A Cedars, Kate M Root, Margaretta E Huchthausen, Brian Akhaphong, Emilyn U Alejandro
Publikováno v:
Hypertension. 79
Gestational hypertension with or without low birth weight is associated with increased risk for Type 2 diabetes in offspring. Pancreatic beta cell mass is set very early in life and can influence whether an individual develops Type 2 diabetes. We pre
Autor:
Kate M. Root, Brian Akhaphong, Margaretta E. Huchthausen, Connor F. Laule, Emilyn U. Alejandro, Jean F. Regal
Publikováno v:
The FASEB Journal. 36
Autor:
Kate M. Root, Brian Akhaphong, Melissa A. Cedars, Alexa M. Molin, Margaretta E. Huchthausen, Connor F. Laule, Ronald R. Regal, Emilyn U. Alejandro, Jean F. Regal
Publikováno v:
Diabetes. 71(12)
Preeclampsia is a pregnancy-specific complication with long-term negative outcomes for offspring, including increased susceptibility to type 2 diabetes (T2D) in adulthood. In a rat reduced uteroplacental perfusion pressure (RUPP) model of chronic pla
Autor:
Jean F Regal, Kathryn E Lillegard, Ashley J Bauer, Barbara J Elmquist, Alex C Loeks-Johnson, Jeffrey S Gilbert
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132063 (2015)
Preeclampsia is characterized by reduced placental perfusion with placental ischemia and hypertension during pregnancy. Preeclamptic women also exhibit a heightened inflammatory state and greater number of neutrophils in the vasculature compared to n
Externí odkaz:
https://doaj.org/article/d6e133cc1279460e8701eef7aabe44dc
Autor:
Kendra J. Towner, Cameron R. Wing, Sherry D. Fleming, Connor F. Laule, Kate M. Root, Jean F. Regal, Evan Odean, Jeffrey S. Gilbert, Cassandra M Hamm
Publikováno v:
Am J Physiol Heart Circ Physiol
Preeclampsia is a prevalent pregnancy complication characterized by new-onset maternal hypertension and inflammation, with placental ischemia as the initiating event. Studies of others have provided evidence for the importance of lymphocytes in place