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pro vyhledávání: '"Jean E. Sealey"'
Pregnant women with chronic hypertension are at risk for increased blood pressure and superimposed preeclampsia (SPE) in late pregnancy. Alterations in the renin-aldosterone system are a feature of normal pregnancy; however, their role in chronic hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a9870e7cf46f956f767afc31d3cacda
https://europepmc.org/articles/PMC6051425/
https://europepmc.org/articles/PMC6051425/
Publikováno v:
American journal of hypertension. 30(9)
BACKGROUND About one-half of all hypertensive adults do not have their blood pressure controlled. They are often prescribed medications that conform to national guidelines but they continue to have elevated blood pressure. This public health problem
Publikováno v:
Journal of Hypertension. 37:e2
Objective:Belief that a particular blood pressure (BP) can separate ‘hypertension’ from ‘normo-tension’ has transformed a ‘risk factor’ into a treatable condition. An arbitrary blood pressure threshold establishes the diagnosis and standa
Publikováno v:
American Journal of Hypertension. 26:727-738
Background Four recent reports revealed differences in survival rates among treated cardiovascular patients taking renin-angiotensin system–blocking drugs. Patients with higher on-treatment plasma renin activity (PRA) levels died sooner of cardiova
Publikováno v:
Кардиоваскулярная терапия и профилактика, Vol 10, Iss 6, Pp 35-41 (2011)
The extent to which the clinical effects of angiotensin receptor blockers (ARB) are related to ambient renin system activity remains poorly defined. Therefore, we measured blood pressure (BP), large (C1) and small (C2) arterial compliance, systemic v
Publikováno v:
American Journal of Hypertension. 24:1181-1186
Background Plasma renin activity (PRA) has been associated with cardiovascular disease mortality (CVD) events among hypertensive patients. We now report a long-term follow-up to assess the enduring association of PRA to CVD and all-cause mortality. m
Autor:
Carmen Merali, Curt H. Grob, Jan Basile, Daniel T. Lackland, Christine Walters, Phillip B. Davis, Jessica Flynn Riehle, Shakaib U. Rehman, John H. Laragh, Brent M. Egan, Jean E. Sealey
Publikováno v:
American Journal of Hypertension. 22:792-801
Undefined pathophysiologic mechanisms likely contribute to unsuccessful antihypertensive drug therapy. The renin test-guided therapeutic (RTGT) algorithm is based on the concept that, irrespective of current drug treatments, subnormal plasma renin ac
Autor:
Jean E. Sealey, John H. Laragh
Publikováno v:
American Journal of Hypertension. 22:112-121
Background Suppressed baseline plasma renin activity (PRA) levels or large reactive increases in renin secretion are two possible reasons for treatment failure with antirenin system drugs. Methods To investigate their prevalence we reanalyzed data fr
Autor:
Jean E. Sealey, John H. Laragh
Publikováno v:
American Journal of Hypertension. 20:587-597
A review of six clinical trials of aliskiren involving >5,000 patients with mild to moderate hypertension indicated that this first of a new class of orally active antihypertensive drugs is no more effective than angiotensin-converting enzyme inhibit
Autor:
Jean E. Sealey, M Brown, R J Johnson, J H Laragh, Tatsuo Shimosawa, J B Standridge, H Gavras, Toshiro Fujita, B M Egan, J I Meltzer, M C Houston, Jon D. Blumenfeld
Publikováno v:
Journal of Human Hypertension. 19:259-266
During the Nineteenth Annual Scientific Meeting of the American Society of Hypertension in New York, NY, on May 20, 2004, a gathering of international hypertension experts was convened to discuss far-reaching aspects of researching and managing hyper