Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Jean Dufer"'
Publikováno v:
Analytical Cellular Pathology, Vol 20, Iss 1, Pp 41-48 (2000)
There is a constant need of features able to characterize potentially metastatic cells among the heterogeneous cell subpopulations which constitute a tumor. Image cytometry of metastatic tumor cells give rise to variable results, partly because of a
Externí odkaz:
https://doaj.org/article/aa97577be6924251a2f3a90aa1d4e0f4
Publikováno v:
Analytical Cellular Pathology, Vol 18, Iss 4, Pp 175-181 (1999)
In tumour cell lines, the resistance of cancer cells to a variety of structurally unrelated chemotherapeutic drugs is termed multidrug‐resistance or MDR. We reported previously that MDR leukemic cells displayed nuclear texture changes, as assessed
Externí odkaz:
https://doaj.org/article/78c3a113f8594ac4883bf7305e9c0817
Autor:
Frank Antonicelli, Aurelie Trussardi-Regnier, Mathilde Poplineau, Aleksandra Kosciarz, Marc Diederich, Michael Schnekenburger, Sylvie Brassart-Pasco, Jean Dufer
Publikováno v:
Molecular Carcinogenesis. 54:24-34
In diseases such as cancer, cells need to degrade the extracellular matrix (ECM) and therefore require high protease levels. Thus, aberrant tissue degradation is associated to matrix metalloproteinases (MMPs) overexpression resulting from different m
Autor:
Dennis Gomez, Aurelie Trussardi-Regnier, Victoria El-Khoury, Françoise Liautaud-Roger, Jean Dufer
Publikováno v:
Cytometry Part A. :109-117
Background Texture analysis of chromatin patterns by image cytometry can be used in the development and refinement of diagnosis and prognosis of cancers and in the follow-up of therapies. However, little is known about the biological mechanisms under
Publikováno v:
Technology in Cancer Research & Treatment. 3:383-391
We attempted to characterize the cellular autofluorescence phenomenon of living HL-60 cells and to appraise its modifications under oxidative stress conditions induced by 1α,25(OH)2D3 (VD3) and its analog EB1089. Autofluorescence emission spectra of
Publikováno v:
Leukemia Research. 28:307-313
Resistance to glucocorticoids (GCs) frequently appears during treatment of hematological malignancies. This study investigates the phenotypical alterations observed in human myeloma cell sublines resistant to glucocorticoids. Using the RPMI8226 cell
Autor:
Stéphanie Struski, Nadine Gruson, Martine Doco-Fenzy, Nicole Michel, Linda Masson, Jean Dufer, Evelyne Ulrich, Gérard Potron, Pascale Cornillet-Lefebvre
Publikováno v:
Cancer Genetics and Cytogenetics. 132:51-54
In order to identify genomic changes associated with drug-resistance acquisition, we performed R-banding karyotyping, fluorescence in situ hybridization, and comparative genomic hybridization to compare a human T-cell lymphoblastic leukemia cell line
Publikováno v:
Biology of the Cell. 93:273-280
Image cytometry was applied to study the intracellular localization of autofluorescence and the influence of an oxidative stress on this emission. K562 erythroleukemia cancer cells were analyzed with a microspectrofluorometer, coupled with a Argon la
Publikováno v:
Leukemia Research. 21:147-152
A role for p53 in the regulation of multidrug-resistance (MDR) has been postulated as wild-type p53 suppresses and mutant p53 specifically activates the mdr1 promoter. Moreover, changes in p53 expression and/or functions could be implicated in drug r
Autor:
Teddy Happillon, Aurelie Trussardi-Regnier, Philippe Bernard, Michel Manfait, Olivier Piot, Frank Antonicelli, Mathilde Poplineau, Jean Dufer
Publikováno v:
Epigenomics
Epigenomics, Future Medicine, 2011, 6 (6), pp.785-794
Epigenomics, Future Medicine, 2011, 3, pp.785-794
Epigenomics, Future Medicine, 2011, 6 (6), pp.785-794
Epigenomics, Future Medicine, 2011, 3, pp.785-794
Aims: Classical biochemical and molecular methods for discerning cells with epigenetic modifications are often biologically perturbing or even destructive. We wondered whether the noninvasive laser tweezer Raman spectroscopy technique allowed the dis