Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jean Cy Wang"'
Autor:
Erkan Baloglu, Sharon Shacham, Jean Cy Wang, Julia Etchin, Amy Saur Conway, Alla Berezovskaya, William Senapedis, A. Thomas Look, Richard Stone, Yosef Landesman, Michael Kauffman, Ilene Galinsky
Publikováno v:
Clinical Cancer Research. 23:39-39
Standard chemotherapy often induces remissions in AML patients, but the disease frequently relapses due to incomplete targeting of leukemia-initiating cells (LICs), emphasizing the need for novel effective treatments. An attractive target for AML the
Autor:
Julia Etchin, Marc R. Mansour, Bonnie Thi Le, Alla Berezovskaya, Dilara McCauley, Andrew L. Kung, Michael Kauffman, Thomas Look, Daniel J. DeAngelo, Sharon Shacham, Ilene Galinsky, Amy Saur Conway, Richard Stone, Alex Kentsis, Weihsu C. Chen, Jean Cy Wang
Publikováno v:
Cancer Research. 75:4445-4445
Current treatments for acute myeloid leukemia (AML) often fail to induce long-term remissions and are toxic to normal tissues, prompting the need to develop new targeted therapies. The frequent disease relapse that is observed in patients with AML is
Autor:
Andreea C. Popescu, John E. Dick, Cynthia J. Guidos, Yan Xing, Julie Yuan, Mark D. Minden, Donna E. Hogge, Gitte Gerhard, Jean Cy Wang, Weihsu C. Chen
Publikováno v:
Cancer Research. 73:907-907
Small molecule inhibitors of Janus kinase 2 (JAK2) such as Ruxolitinib and SAR302503 have demonstrated efficacy in clinical trials for treatment of myeloproliferative disorders. Activated JAK2 signaling has been reported in some acute myeloid leukemi
Autor:
Liqing Jin, Mark D. Minden, John E. Dick, Olga I. Gan, Armando G. Poeppl, Jean Cy Wang, Tatiana K. Prasolava, Alexandre Theocharides, Jayne S. Danska
Publikováno v:
Blood. 114:476-476
Abstract 476 Introduction: A large body of work has shown that acute myeloid leukemia (AML) clones are hierarchically organized and maintained by leukemia initiating cells (AML-LSC). However, little is known about molecular regulators that govern AML