Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Jean Claude Madelmont"'
Autor:
Elisabeth Miot-Noirault, Aurélien Vidal, Philippe Auzeloux, Jean-Claude Madelmont, Jean Maublant, Nicole Moins
Publikováno v:
Molecular Imaging, Vol 7 (2008)
This study aimed to report the first single-photon emission computed tomographic (SPECT) imaging of articular cartilage in mice using 99m Tc-NTP 15-5 radiotracer. Mice intravenously injected with 99m Tc-NTP 15-5 were submitted to (1) dynamic planar i
Externí odkaz:
https://doaj.org/article/7041855d52894ee68fee9fbe722492fc
Autor:
Jean-Claude Madelmont, Eric Debiton, Marie-Josèphe Galmier, Gérard Ledoigt, Bernard Griffaut, Ana Mustel
Publikováno v:
Advances in Biological Chemistry. :485-500
Plants can respond to traumatism by synthesis and secretion of defence molecules. Wound-healing and desiccation stress of pieces of potato tuber parenchyma (Solanum tuberosum) promoted the secretion of a patatin-like phospholipase A2, PLA2 (EC.3.1.1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2edc7a4e5032c6c1c255fcc552f91cf
https://doi.org/10.4236/abc.2013.35053
https://doi.org/10.4236/abc.2013.35053
Autor:
Vincent Gaumet, Claire Denis, Aurélien Vidal, Philippe Auzeloux, Jean-Claude Madelmont, Elisabeth Miot - Noirault, Jean-Michel CHEZAL
Publikováno v:
France, Patent n° : WO2016016272 (A1). 2016
HAL
HAL
The present invention concerns compounds of formula (I):their process of preparation and compositions thereof. The present invention also concerns their use as diagnostic agent in PET imaging.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::51ea4a56b0ace38a602c3ed5fb0b8344
https://hal.archives-ouvertes.fr/hal-02885526
https://hal.archives-ouvertes.fr/hal-02885526
Autor:
Jean-Michel Chezal, Anne-Sophie Jarrousse, Fernand Leal, Jacques Métin, Marie-Josèphe Galmier, Jacques Sauzière, Magali Vivier, Maryse Rapp, Elisabeth Miot-Noirault, Valérie Weber, Jean-Claude Madelmont
Publikováno v:
European Journal of Medicinal Chemistry. 46:5705-5710
The proteasome is a promising target in cancer therapy. However, it is ubiquitous and its inhibitors cause side effects. To target melanoma cells we synthesized new peptide aldehyde and vinylsulfone inhibitors of the proteasome conjugated to the mela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81a69ec293e33217fc0dbb5c4b5daab0
https://doi.org/10.1016/j.ejmech.2011.07.037
https://doi.org/10.1016/j.ejmech.2011.07.037
First ex vivo study demonstrating that 99mTc-NTP 15-5 radiotracer binds to human articular cartilage
Autor:
Philippe Auzeloux, Marc Filaire, Jean-Claude Madelmont, Jean-Michel Chezal, Elisabeth Miot-Noirault, Stéphane Boisgard, Damien Culot, Aurélien Vidal, Florent Cachin, Serge Askienazy
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 38:2077-2082
Preclinical data pointed to (99m)Tc-NTP 15-5 as a good candidate for single photon emission computed tomography (SPECT) imaging of cartilaginous disease. We set out to investigate and quantify (99m)Tc-NTP 15-5 ex vivo uptake by human articular cartil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::031cd8cb81c7f8cbe87d27bca4db9167
https://doi.org/10.1007/s00259-011-1890-1
https://doi.org/10.1007/s00259-011-1890-1
Autor:
Maryline Gardette, Ting-Dee Wu, Nicole Moins, Elisabeth Miot-Noirault, Nicolas Desbois, Jean-Claude Madelmont, Pierre Labarre, Mathilde Bonnet, Jean-Michel Chezal, Janine Papon, Jean-Luc Guerquin-Kern
Publikováno v:
Investigational New Drugs. 29:1253-1263
The increasing incidence of melanoma and the lack of effective therapy on the disseminated form have led to an urgent need for new specific therapies. Several iodobenzamides or analogs are known to possess specific affinity for melanoma tissue. New h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a557599c976b5b7d3440d045fc1d474a
https://doi.org/10.1007/s10637-010-9471-x
https://doi.org/10.1007/s10637-010-9471-x
Autor:
Jean-Michel Chezal, Florence Mishellany, Mathilde Bonnet, Jean-Claude Madelmont, Elisabeth Miot-Noirault, Frédérique Penault-Llorca, Janine Papon, Anne Cayre, Nicole Moins
Publikováno v:
Pigment Cell & Melanoma Research. 23:e1-e11
Targeted internal radionuclide therapy (TRT) could be an efficient, specific way to treat disseminated melanoma. Based on a previous pharmacomodulation study, we selected a quinoxaline-derived molecule (ICF01012) for its melanin specificity and kinet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a57b2015c07d6893b60b6083d7f8d0b
https://doi.org/10.1111/j.1755-148x.2010.00716.x
https://doi.org/10.1111/j.1755-148x.2010.00716.x
Autor:
Pascal Coudert, Jean-Michel Chezal, Elisabeth Miot-Noirault, Eric Debiton, Jean-Claude Madelmont, Bastien Reux, Valérie Weber
Publikováno v:
Investigational New Drugs. 29:424-433
Our strategy is to increase drug accumulation in target tumour cells using specific "vectors" tailored to neoplastic tissue characteristics, which ideally are not found in healthy tissues. The aim of this work was to use 2-fluoro-2-deoxyglucose (FDG)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb60bff5dc655eabca4f7dfc81b31d28
https://doi.org/10.1007/s10637-009-9371-0
https://doi.org/10.1007/s10637-009-9371-0
Autor:
Jean Claude Madelmont, Elisabeth Miot-Noirault, Nicole Moins, Philippe Pastoureau, Janine Papon, Jean Maublant, Michèle Borel
Publikováno v:
Journal of Proteome Research. 8:2594-2600
This study assessed the 1H HRMAS NMR spectroscopic profile of articular cartilage in both physiological and osteoarthitic situations. One-dimensional and two-dimensional 1H HRMAS NMR spectra were obtained from the tibial plateau cartilage of healthy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4acab1332a6fc612cc4d5fe978f2de98
https://doi.org/10.1021/pr8009963
https://doi.org/10.1021/pr8009963
Autor:
Elisabeth Miot-Noirault, Françoise Rédini, S. Boisgard, Nicole Moins, Jean Maublant, Aurélien Vidal, Michel D'Incan, Philippe Auzeloux, Florent Cachin, Charles Merlin, Jean-Michel Chezal, Mathilde Bonnet-Duquennoy, A. Veyre, Marc Filaire, D. Mestas, Antony Kelly, Jean-Claude Madelmont
Publikováno v:
Médecine Nucléaire. 33:161-167
La plupart des programmes de recherche sur les nouveaux radiopharmaceutiques portent actuellement sur les traceurs utilises en tomographie par emission de positons (TEP). Seules quelques equipes continuent a travailler sur des nouveaux traceurs non f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0b3e1ddb55d82f05383bae7279f9d01
https://doi.org/10.1016/j.mednuc.2009.01.003
https://doi.org/10.1016/j.mednuc.2009.01.003