Výsledky vyhledávání - "Jean Claude Drapier"

Akademický článek

Peroxiredoxin post-translational modifications by redox messengers

Autor: Sylvie Riquier, Jacques Breton, Kahina Abbas, David Cornu, Cécile Bouton, Jean-Claude Drapier

Publikováno v: Redox Biology, Vol 2, Iss C, Pp 777-785 (2014)

Peroxiredoxins (Prxs) are a family of thiol peroxidases that participate in hydroperoxide detoxification and regulates H2O2 signaling. In mammals, the four typical 2-Cys Prxs (Prxs 1, 2, 3 and 4) are known to regulate H2O2-mediated intracellular sign

Externí odkaz: https://doaj.org/article/f8e73d3b7f2f4fe8a1b385d782b1cb02

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Nitric oxide activates an Nrf2/sulfiredoxin antioxidant pathway in macrophages

Autor: Jean-Claude Drapier, Michel B. Toledano, Jacques Breton, Jérôme Bignon, Anne-Gaëlle Planson, Cécile Bouton, Kahina Abbas, Cendrine Seguin, Sylvie Riquier

Publikováno v: Free Radical Biology and Medicine
Free Radical Biology and Medicine, Elsevier, 2011, 51 (1), pp.107-114. ⟨10.1016/j.freeradbiomed.2011.03.039⟩

International audience; Malaria represents a major public health problem and an important cause of mortality and morbidity. The malaria parasites are becoming resistant to drugs used to treat the disease and still no efficient vaccine has been develo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e4d5b92cf376303690ee4f43641bf1
https://doi.org/10.1016/j.freeradbiomed.2011.03.039

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Frataxin deficiency causes upregulation of mitochondrial Lon and ClpP proteases and severe loss of mitochondrial Fe-S proteins

Autor: Marie Wattenhofer-Donzé, Jean-Claude Drapier, Blanche Guillon, Bertrand Friguet, Anne-Laure Bulteau, Hélène Puccio, Stéphane Schmucker, Cécile Bouton

Publikováno v: FEBS Journal. 276:1036-1047

Friedreich ataxia (FRDA) is a rare hereditary neurodegenerative disease characterized by progressive ataxia and cardiomyopathy. The cause of the disease is a defect in mitochondrial frataxin, an iron chaperone involved in the maturation of Fe-S clust

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::812d3663eaa730fe500720bfcf6096db
https://doi.org/10.1111/j.1742-4658.2008.06847.x

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Regulation of the cysteine desulfurase Nfs1 and the scaffold protein IscU in macrophages stimulated with interferon-γ and lipopolysaccharide

Autor: Cédric Fosset, Frédéric Canal, Cécile Bouton, Jean-Claude Drapier, Marie-Jeanne Chauveau

Publikováno v: Archives of Biochemistry and Biophysics
Archives of Biochemistry and Biophysics, Elsevier, 2007, 465 (1), pp.282-92. ⟨10.1016/j.abb.2007.06.003⟩

International audience; Biogenesis of iron-sulfur (Fe-S) clusters in mammals involves a complex mitochondrial machinery that provides inorganic sulfide and iron for their assembly and insertion into apo-proteins. Mechanisms of Fe-S cluster assembly a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b79675ca862e870285d67e6732792648
https://doi.org/10.1016/j.abb.2007.06.003

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Hypericin Activates L-Type Ca2+ Channels in Cardiac Myocytes

Autor: Marie-Jeanne Chauveau, Michel Negrerie, Martin-Pierre Sauviat, Anthony Colas, Jean-Claude Drapier

Publikováno v: Journal of Natural Products
Journal of Natural Products, American Chemical Society, 2007, 70 (4), pp.510-514. ⟨10.1021/np060309h⟩

The effects and the mode of action of hypericin (1) were studied, in the dark, on the action potential (AP) and the L-type Ca2+ channel of frog atrial heart muscle, using intracellular microelectrode and patch-clamp techniques, respectively. In the p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffc5eb2548a4c2495c30f86eb1c2d592
https://doi.org/10.1021/np060309h

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STAT5 proteins are involved in down-regulation of iron regulatory protein 1 gene expression by nitric oxide

Autor: Jean-Claude Drapier, Ana Sofia Gonçalves, Françoise Muzeau, Ewa Smuda, Paweł Lipiński, Rafał R. Starzyński, Zofia Tyrolczyk, Carole Beaumont

Publikováno v: Biochemical Journal
Biochemical Journal, Portland Press, 2006, 400(Part2), pp.367-375. ⟨10.1042/BJ20060623⟩

RNA-binding activity of IRP1 (iron regulatory protein 1) is regulated by the insertion/extrusion of a [4Fe-4S] cluster into/from the IRP1 molecule. NO (nitic oxide), whose ability to activate IRP1 by removing its [4Fe-4S] cluster is well known, has a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41147fc3f751c28809580432b918813e
https://doi.org/10.1042/bj20060623

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RNA Silencing of Mitochondrial m-Nfs1 Reduces Fe-S Enzyme Activity Both in Mitochondria and Cytosol of Mammalian Cells

Autor: Marie-Jeanne Chauveau, Cécile Bouton, Blanche Guillon, Jean-Claude Drapier, Cédric Fosset, Frédéric Canal

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2006, 281(35), pp.25398-25406. ⟨10.1074/jbc.M602979200⟩

In prokaryotes and yeast, the general mechanism of biogenesis of iron-sulfur (Fe-S) clusters involves activities of several proteins among which IscS and Nfs1p provide, through cysteine desulfuration, elemental sulfide for Fe-S core formation. Althou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c70867ed48d27ec368e0b360fe9660
https://doi.org/10.1074/jbc.m602979200

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Endogenous Nitration of Iron Regulatory Protein-1 (IRP-1) in Nitric Oxide-producing Murine Macrophages

Autor: Cécile Bouton, Jean-Claude Drapier, Deyarina Gonzalez

Publikováno v: Journal of Biological Chemistry. 279:43345-43351

Iron regulatory protein-1 (IRP-1) is a bifunctional [4Fe-4S] protein that functions as a cytosolic aconitase or as a trans-regulatory factor controlling iron homeostasis at a post-transcriptional level. Because IRP-1 is a sensitive target protein for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dfb416424625b950b0179386bfa53fa8
https://doi.org/10.1074/jbc.m401889200

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Peroxynitrite and Nitric Oxide Differently Target the Iron−Sulfur Cluster and Amino Acid Residues of Human Iron Regulatory Protein 1

Autor: Tony A. Mattioli, Charilaos Goussias, Jean-Claude Drapier, Emmanuelle Soum, Cécile Bouton, Jean-Marc Moulis, Xavier Brazzolotto

Publikováno v: Biochemistry. 42:7648-7654

Iron regulatory protein 1 (IRP1) is a redox-sensitive protein which exists in two active forms in the cytosol of eukaryotic cells. Holo-IRP1 containing a [4Fe-4S] cluster exhibits aconitase activity which catalyzes the isomerization of citrate and is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d14e5a7ec3e2b99a3a1031b606a522
https://doi.org/10.1021/bi030041i

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Recycling of RNA Binding Iron Regulatory Protein 1 into an Aconitase after Nitric Oxide Removal Depends on Mitochondrial ATP

Autor: Jean-Claude Drapier, Cécile Bouton, Marie-Jeanne Chauveau, Sylvie Lazereg

Publikováno v: Journal of Biological Chemistry. 277:31220-31227

Iron regulatory proteins (IRPs) control iron metabolism by specifically interacting with iron-responsive elements (IREs) on mRNAs. Nitric oxide (NO) converts IRP-1 from a [4Fe-4S] aconitase to a trans-regulatory protein through Fe-S cluster disassemb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03864493b00f3ef0afd9a7191d4614af
https://doi.org/10.1074/jbc.m203276200

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