Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Jean Claude Camus"'
Publikováno v:
Aquatic Ecology. 35:195-205
The ecological assessment of freshwater ecosystems necessitates to consider (i) the operational biological classification for defining a range of ecosystem alterations, (ii) operational biomonitoring tools fulfilling the requirements of the classific
Autor:
Reinhold Tacke, Carsten Strohmann, Günter Lambrecht, Roland Feifel, Ernst Mutschler, Jean Claude Camus, Magali Waelbroeck, J.F. Rodrigues de Miranda, K. Rafeiner, Michèle Tastenoy
Publikováno v:
British Journal of Pharmacology. 112:505-514
1. We have compared the binding properties of several hexocyclium and sila-hexocyclium derivatives to muscarinic M1 receptors (in rat brain, human neuroblastoma (NB-OK 1) cells and calf superior cervical ganglia), rat heart M2 receptors, rat pancreas
Autor:
Michèle Tastenoy, Jean Christophe, Ernst Mutschler, Reinhold Tacke, Magali Waelbroeck, Günter Lambrecht, Jean Claude Camus
Publikováno v:
European Journal of Pharmacology: Molecular Pharmacology. 189:135-142
The goals of the present study were: (1) to investigate thc binding properlies oi (R)- and (S)-procyclidine and two aehiral derivatives of muscarinie M1• M2 and M4 reeeptor subtypes and (2) to identify the interaetions which allow these receptors t
Autor:
Ernst Mutschler, Jean Claude Camus, Michèle Tastenoy, Jean Christophe, Carsten Strohmann, Günter Lambrecht, Lise Schjelderup, Arne J. Aasen, Magali Waelbroeck, Reinhold Tacke
Publikováno v:
European journal of pharmacology. 227(1)
Wc invcstigatcd thc binding properlies of thc (R)- and (Sl-cnantiomcrs of thc muscarinic antagonists trihcxyphcnidyl, procyclidinc, hcxahydro-difcnidol. p-fluoro-hcxahydro-difcnidol. hcxbutinol, p-fluoro-hcxbutinnl. and thcir corrcsponding methiodidc
Publikováno v:
British journal of pharmacology. 105(1)
1. We compared the binding properties of 4-diphenyl-acetoxy-N-methyl-piperidine methiodide (4-DAMP) and nine analogues of this compound on muscarinic receptors of human neuroblastoma NB-OK1 cells (M1 subtype), rat heart (M2 subtype), rat pancreas (M3
Autor:
Jean Christophe, Michèle Tastenoy, Jean Claude Camus, Ernst Mutschler, Carsten Strohmann, Reinhold Tacke, Günter Lambrecht, Magali Waelbroeck
Hexahydro-sila-difenidoJ and eight analogues behaved as simple cumpetitive inhibitors of eHJN·methyl·scopoJamine binding to homogenates frorn human neuroblastoma NB-OK 1 cells (MI sites), rat heart (M 2 sites), rat pancreas (M 3 sites), and rat str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f25286b7d4728f43ce7830151ccc621
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-64128
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-64128
Autor:
Jean Claude Camus, Ernst Mutschler, Carsten Strohmann, Magali Waelbroeck, Michèle Tastenoy, Günter Lambrecht, Jean Christophe, Reinhold Tacke
Publikováno v:
Chirality. 3(2)
(R)-Hexahydro-difenidol has a higher affinity for M\(_1\) receptors in NB-OK 1 cells, pancreas M\(_3\) and striatum M\(_4\) receptors (pKi 7.9 to 8.3) than for cardiac M2 receptors (pKi 7 .0). (8)-Hexahydro-difenidol, by contrast, is nonselective (pK
Publikováno v:
Life Sciences. 52:576
Autor:
David H. Coy, Jean Claude Camus, Jean Christophe, Philippe De Neef, Patrick Robberecht, Mark L. Heiman, Magali Waelbroeck
Publikováno v:
Endocrinology. 117:1759-1764
The efficacy and potency of 14 GH-releasing factor (GRF) analogs, substituted in position 1 to 7, on adenylate cyclase activation in crude homogenates from rat anterior pituitary were related to those of human pancreatic GRF(1-29)-amide and vasoactiv
Publikováno v:
Life Sciences. 41:2235-2240
The antagonist binding properties of rat pancreatic and cardiac muscarinic receptors were compared. In both tissues pirenzepine (PZ) had a low affinity for muscarinic receptors labelled by ( 3 H)N-methylscopolamine (( 3 )NMS) (K D values of 140 and 2