Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Jean Christopher, Chamcheu"'
Publikováno v:
Cells, Vol 13, Iss 17, p 1500 (2024)
Transduction of molecular signaling is a fundamental mechanism that allows a living cell to communicate internally with other cells and its environment through chemical or physical signals, thereby maintaining its structural integrity and triggering
Externí odkaz:
https://doaj.org/article/5551386fee6a4b5f89c2a8e2c85f1dba
Autor:
Khandoker Usran Ferdous, Mulu Z. Tesfay, Aleksandra Cios, Randal S. Shelton, Conner Hartupee, Alicja Urbaniak, Jean Christopher Chamcheu, Michail N. Mavros, Emmanouil Giorgakis, Bahaa Mustafa, Camila C. Simoes, Isabelle R. Miousse, Alexei G. Basnakian, Omeed Moaven, Steven R. Post, Martin J. Cannon, Thomas Kelly, Bolni Marius Nagalo
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1596 (2024)
About one-fourth of patients with pancreatic ductal adenocarcinoma (PDAC) are categorized as borderline resectable (BR) or locally advanced (LA). Chemotherapy and radiation therapy have not yielded the anticipated outcomes in curing patients with BR/
Externí odkaz:
https://doaj.org/article/26e24818024f44df999d68d0ff29c36b
Autor:
Peihong Lyu, Huifang Li, Junzhao Wan, Ying Chen, Zhen Zhang, Panpan Wu, Yinsheng Wan, Navindra P. Seeram, Jean Christopher Chamcheu, Chang Liu, Hang Ma
Publikováno v:
Antioxidants, Vol 13, Iss 4, p 478 (2024)
Cannabis and its major cannabinoid cannabidiol (CBD) are reported to exhibit anticancer activity against skin tumors. However, the cytotoxic effects of other minor cannabinoids and synthetic CBD derivatives in melanoma are not fully elucidated. Herei
Externí odkaz:
https://doaj.org/article/1f5f154c451540f1afdae6bf9fa97b86
Autor:
Fabio Esposito, Nicolino Pala, Mauro Carcelli, Samuel T. Boateng, Paolo S. D’Aquila, Alberto Mariani, Sandro Satta, Jean Christopher Chamcheu, Mario Sechi, Vanna Sanna
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Natural α-glucosidase inhibitors from plant-based foods such as catechins offer an attractive strategy for their potential anti-diabetic effects. In this study, infusions of three different tea types (green, white, and oolong) were investigated for
Externí odkaz:
https://doaj.org/article/a8426010c28e45e2be3e2b777b431689
Autor:
Samuel T. Boateng, Tithi Roy, Kara Torrey, Uchechi Owunna, Sergette Banang-Mbeumi, David Basnet, Eleonora Niedda, Alexis D. Alexander, Denzel El Hage, Siriki Atchimnaidu, Bolni Marius Nagalo, Dinesh Aryal, Ann Findley, Navindra P. Seeram, Tatiana Efimova, Mario Sechi, Ronald A. Hill, Hang Ma, Jean Christopher Chamcheu, Siva Murru
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Twenty-five azole compounds (P1–P25) were synthesised using regioselective base-metal catalysed and microwave-assisted approaches, fully characterised by high-resolution mass spectrometry (HRMS), nuclear magnetic resonance (NMR), and infrared spect
Externí odkaz:
https://doaj.org/article/6723a7780c15410686963a027f101484
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/dfe70a0734a24cc39fc5ad5220e54101
Autor:
Tithi Roy, Sergette Banang-Mbeumi, Samuel T. Boateng, Emmanuelle M. Ruiz, Roxane-Cherille N. Chamcheu, Lin Kang, Judy A. King, Anthony L. Walker, Bolni Marius Nagalo, Konstantin G. Kousoulas, Stephane Esnault, Shile Huang, Jean Christopher Chamcheu
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Psoriasis is a chronic autoimmune inflammatory skin disorder characterized by epidermal hyperplasia and aberrant immune response. In addition to aberrant cytokine production, psoriasis is associated with activation of the Akt/mTOR pathway. mTOR/S6K1
Externí odkaz:
https://doaj.org/article/aac2a82940c348b5a3ec4d64743b35a6
Autor:
Yuguo Zhang, Musa Gabere, Mika A. Taylor, Camila C. Simoes, Chelsae Dumbauld, Oumar Barro, Mulu Z. Tesfay, Alicia L. Graham, Khandoker Usran Ferdous, Alena V. Savenka, Jean Christopher Chamcheu, Charity L. Washam, Duah Alkam, Allen Gies, Stephanie D. Byrum, Matteo Conti, Steven R. Post, Thomas Kelly, Mitesh J. Borad, Martin J. Cannon, Alexei Basnakian, Bolni M. Nagalo
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
It has long been known that oncolytic viruses wield their therapeutic capability by priming an inflammatory state within the tumor and activating the tumor immune microenvironment, resulting in a multifaceted antitumor immune response. Vaccine-derive
Externí odkaz:
https://doaj.org/article/cc4969f03b474994ad64d25b34a6caa6
Autor:
Tithi Roy, Samuel T. Boateng, Mohammad B. Uddin, Sergette Banang-Mbeumi, Rajesh K. Yadav, Chelsea R. Bock, Joy T. Folahan, Xavier Siwe-Noundou, Anthony L. Walker, Judy A. King, Claudia Buerger, Shile Huang, Jean Christopher Chamcheu
Publikováno v:
Cells, Vol 12, Iss 12, p 1671 (2023)
The dysregulated phosphatidylinositol-3-kinase (PI3K)-Akt-mammalian target of rapamycin (mTOR) signaling pathway has been implicated in various immune-mediated inflammatory and hyperproliferative dermatoses such as acne, atopic dermatitis, alopecia,
Externí odkaz:
https://doaj.org/article/7b00fedceb10450bb4ff237acb393a0b
Autor:
Leseho Swana, Bienvenu Tsakem, Jacqueline V. Tembu, Rémy B. Teponno, Joy T. Folahan, Jarmo-Charles Kalinski, Alexandros Polyzois, Guy Kamatou, Louis P. Sandjo, Jean Christopher Chamcheu, Xavier Siwe-Noundou
Publikováno v:
Pharmaceuticals, Vol 16, Iss 5, p 775 (2023)
Dacryodes Vahl. species, belonging to the Burseraceae family, are widely used in traditional medicine in tropical regions to treat a range of ailments including malaria, wounds, tonsillitis, and ringworms. This review discusses the distribution, ethn
Externí odkaz:
https://doaj.org/article/dff9025e4f1e4b6faf30e7bcd387abe4