Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Jean Christophe Deloulme"'
Autor:
Jean Christophe Deloulme, Maxime Leclercq, Olivier Deschaux, Gemma Flore, Laetitia Capellano, Chiara Tocco, Barbara Yael Braz, Michèle Studer, Hana Lahrech
Publikováno v:
Neurobiology of Disease, Vol 193, Iss , Pp 106455- (2024)
White matter (WM) tract formation and axonal pathfinding are major processes in brain development allowing to establish precise connections between targeted structures. Disruptions in axon pathfinding and connectivity impairments will lead to neural
Externí odkaz:
https://doaj.org/article/a331958f558f42d6a5b3f09b4ca5e0ae
Autor:
Leticia Peris, Mariano Bisbal, José Martinez-Hernandez, Yasmina Saoudi, Julie Jonckheere, Marta Rolland, Muriel Sebastien, Jacques Brocard, Eric Denarier, Christophe Bosc, Christophe Guerin, Sylvie Gory-Fauré, Jean Christophe Deloulme, Fabien Lanté, Isabelle Arnal, Alain Buisson, Yves Goldberg, Laurent Blanchoin, Christian Delphin, Annie Andrieux
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Microtubule-associated protein 6 (MAP6) is known to be important for synaptic plasticity and cognition, supposedly via interaction with microtubules. Here, the authors found that MAP6 is crucial for the stabilisation of enlarged synapses through its
Externí odkaz:
https://doaj.org/article/9a70b96ea1e0471499f443604529b0ce
Evaluation of kernel low-rank compressed sensing in preclinical diffusion magnetic resonance imaging
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Compressed sensing (CS) is widely used to accelerate clinical diffusion MRI acquisitions, but it is not widely used in preclinical settings yet. In this study, we optimized and compared several CS reconstruction methods for diffusion imaging. Differe
Externí odkaz:
https://doaj.org/article/756ed4b6452341a8aeee651122909dd3
Autor:
Benoît Boulan, Charlotte Ravanello, Amandine Peyrel, Christophe Bosc, Christian Delphin, Florence Appaix, Eric Denarier, Alexandra Kraut, Muriel Jacquier-Sarlin, Alyson Fournier, Annie Andrieux, Sylvie Gory-Fauré, Jean-Christophe Deloulme
Publikováno v:
eLife, Vol 10 (2021)
Neurodevelopmental axonal pathfinding plays a central role in correct brain wiring and subsequent cognitive abilities. Within the growth cone, various intracellular effectors transduce axonal guidance signals by remodeling the cytoskeleton. Semaphori
Externí odkaz:
https://doaj.org/article/2e6f528332b64a189ebf72241910d1a6
Autor:
Camille Cuveillier, Benoit Boulan, Charlotte Ravanello, Eric Denarier, Jean-Christophe Deloulme, Sylvie Gory-Fauré, Christian Delphin, Christophe Bosc, Isabelle Arnal, Annie Andrieux
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
The development and function of the central nervous system rely on the microtubule (MT) and actin cytoskeletons and their respective effectors. Although the structural role of the cytoskeleton has long been acknowledged in neuronal morphology and act
Externí odkaz:
https://doaj.org/article/11217eea853d48bcac49048476cb3137
Autor:
Julie Bruyère, Yah-Se Abada, Hélène Vitet, Gaëlle Fontaine, Jean-Christophe Deloulme, Aurélia Cès, Eric Denarier, Karin Pernet-Gallay, Annie Andrieux, Sandrine Humbert, Marie-Claude Potier, Benoît Delatour, Frédéric Saudou
Publikováno v:
eLife, Vol 9 (2020)
Studies have suggested that amyloid precursor protein (APP) regulates synaptic homeostasis, but the evidence has not been consistent. In particular, signaling pathways controlling APP transport to the synapse in axons and dendrites remain to be ident
Externí odkaz:
https://doaj.org/article/b038de28dd5a440288feebeb14342e19
Autor:
Benoit Boulan, Anne Beghin, Charlotte Ravanello, Jean-Christophe Deloulme, Sylvie Gory-Fauré, Annie Andrieux, Jacques Brocard, Eric Denarier
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0234529 (2020)
Morphometry characterization is an important procedure in describing neuronal cultures and identifying phenotypic differences. This task usually requires labor-intensive measurements and the classification of numerous neurites from large numbers of n
Externí odkaz:
https://doaj.org/article/893e99dfad844856ba43387126c2d177
Autor:
Jean-Claude Platel, Alexandra Angelova, Stephane Bugeon, Jenelle Wallace, Thibault Ganay, Ilona Chudotvorova, Jean-Christophe Deloulme, Christophe Béclin, Marie-Catherine Tiveron, Nathalie Coré, Venkatesh N Murthy, Harold Cremer
Publikováno v:
eLife, Vol 8 (2019)
Adult neurogenesis in the olfactory bulb (OB) is considered as a competition in which neurons scramble during a critical selection period for integration and survival. Moreover, newborn neurons are thought to replace pre-existing ones that die. Despi
Externí odkaz:
https://doaj.org/article/427391c4f49d48d58d986b81371466c3
Publikováno v:
Magnetic Resonance Materials in Physics, Biology and Medicine.
Autor:
Barbara Yael Braz, Doris Wennagel, Leslie Ratié, Diego Alves Rodrigues de Souza, Jean Christophe Deloulme, Emmanuel L. Barbier, Alain Buisson, Fabien Lanté, Sandrine Humbert
Publikováno v:
Science
Science, 2022, 377 (6613), pp.eabq5011. ⟨10.1126/science.abq5011⟩
Science, 2022, 377 (6613), pp.eabq5011. ⟨10.1126/science.abq5011⟩
International audience; Recent evidence has shown that even mild mutations in the Huntingtin gene that are associated with late-onset Huntington’s disease (HD) disrupt various aspects of human neurodevelopment. To determine whether these seemingly