Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Jean Champagnat"'
Autor:
Laure Lecoin, Bowen Dempsey, Alexandra Garancher, Steeve Bourane, Pierre-Louis Ruffault, Marie-Pierre Morin-Surun, Nathalie Rocques, Martyn Goulding, Alain Eychène, Celio Pouponnot, Gilles Fortin, Jean Champagnat
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Apneas are associated with many pathological conditions. Here, the authors show in a mouse model that stabilization of the transcription factor Mafa in brainstem GABAergic neurons may contribute to apnea, by decreasing motor drive to muscles controll
Externí odkaz:
https://doaj.org/article/4e5a7c519af7455ca59539ab8c61aa59
Autor:
Laure Lecoin, Bowen Dempsey, Alexandra Garancher, Steeve Bourane, Marie-Pierre Morin-Surun, Nathalie Rocques, Alain Eychene, Celio Pouponnot, Gilles Fortin, Jean Champagnat
Publikováno v:
Médecine du Sommeil. 20:45
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60a6882c0b2d73b07544f68bf74e9f40
https://doi.org/10.1016/j.msom.2023.01.077
https://doi.org/10.1016/j.msom.2023.01.077
Publikováno v:
Neural Plasticity, Vol 7, Iss 1-2, Pp 9-18 (2000)
The GABA-withdrawal syndrome (GWS) is a model of local status epilepticus following the interruption of a chronic GABA infusion into the rat somatomotor cortex. GWS is characterized by focal epileptic electroencephalographic discharges and associated
Externí odkaz:
https://doaj.org/article/e5213b1203b54b58bd61919d45a71424
Autor:
Muriel Thoby-Brisson, Julien Bouvier, Derrick M Glasco, Michelle E Stewart, Charlotte Dean, Jennifer N Murdoch, Jean Champagnat, Gilles Fortin, Anand Chandrasekhar
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31140 (2012)
The proper development and maturation of neuronal circuits require precise migration of component neurons from their birthplace (germinal zone) to their final positions. Little is known about the effects of aberrant neuronal position on the functioni
Externí odkaz:
https://doaj.org/article/616b6ba8dfe244c9ab9ef7793ca49140
Autor:
Julien Bouvier, Carmen Birchmeier, Gilles Fortin, Marie-Pierre Morin-Surun, Jean Champagnat, Luis R. Hernandez-Miranda, Justyna Cholewa-Waclaw, Pierre-Louis Ruffault, Niccolò Zampieri, Andrew J. Murray, Jean-François Brunet, Elodie Ey
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2017, 114 (30), pp.8095-8100. ⟨10.1073/pnas.1702893114⟩
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (30), pp.8095-8100. ⟨10.1073/pnas.1702893114⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2017, 114 (30), pp.8095-8100. ⟨10.1073/pnas.1702893114⟩
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (30), pp.8095-8100. ⟨10.1073/pnas.1702893114⟩
International audience; Vocalization in young mice is an innate response to isolation or mechanical stimulation. Neuronal circuits that control vocalization and breathing overlap and rely on motor neurons that innervate laryngeal and expiratory muscl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b9eead34405859e1cde91cb73f943c0
https://pubmed.ncbi.nlm.nih.gov/28698373
https://pubmed.ncbi.nlm.nih.gov/28698373
Autor:
L.C. Mc Kay, E. Domínguez-del-Toro, N. Voituron, A. Frugière, R. Romero-Granados, F. Saadani-Makki, Jean Champagnat, L. Bodineau
Publikováno v:
Neuroscience. 194:95-111
Acute hypoxia elicits a biphasic respiratory response characterized in the newborn by a transient hyperventilation followed by a severe decrease in respiratory drive known as hypoxic respiratory depression. Medullary O(2) chemosensitivity is known to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323bb5baa620f986c41e3503cb1edd96
https://doi.org/10.1016/j.neuroscience.2011.07.062
https://doi.org/10.1016/j.neuroscience.2011.07.062
Publikováno v:
Philosophical Transactions of the Royal Society B: Biological Sciences. 364:2469-2476
TheHoxgenetic network plays a key role in the anteroposterior patterning of the rhombencephalon at pre- and early-segmental stages of development of the neural tube. In the mouse, it controls development of the entire brainstem respiratory neuronal n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8edee7423a671443f27652ddff5b83
https://doi.org/10.1098/rstb.2009.0090
https://doi.org/10.1098/rstb.2009.0090
Autor:
Patrick Charnay, Mattias Karlen, Jean Champagnat, Gilles Fortin, Ning Wu, Muriel Thoby-Brisson
Publikováno v:
Nature Neuroscience
Nature Neuroscience, Nature Publishing Group, 2009, 12 (8), pp.1028-1035. ⟨10.1038/nn.2354⟩
Nature Neuroscience, Nature Publishing Group, 2009, 12 (8), pp.1028-1035. ⟨10.1038/nn.2354⟩
International audience; The hindbrain transcription factors Phox2b and Egr2 (also known as Krox20) are linked to the development of the autonomic nervous system and rhombomere-related regulation of breathing, respectively. Mutations in these proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e029ceba3566e556340653877c442aa
https://doi.org/10.1038/nn.2354
https://doi.org/10.1038/nn.2354
Publikováno v:
Journal of Neurophysiology. 101:591-602
To better characterize the emergence of spontaneous neuronal activity in the developing hindbrain, spontaneous activity was recorded optically from defined projection neuron populations in isolated preparations of the brain stem of the chicken embryo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a4211376323e4b1d1cdd82c8ff8b46
https://doi.org/10.1152/jn.90835.2008
https://doi.org/10.1152/jn.90835.2008
Autor:
Ludovic Wrobel, Jean Champagnat, Fabrice Chatonnet, M. Ogier, Sandra Autran, Valérie Mézières, C. Taeron, Muriel Thoby-Brisson, Heather McLean
Publikováno v:
Neuroscience. 145:384-392
Mutations of genes encoding Phox2a or Phox2b transcription factors induce modifications of different brainstem neuronal networks. Such modifications are associated with defects in breathing behavior at birth. In particular, an abnormal breathing freq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d908cfb9f7d8e5bac5509579efbc1bd4
https://doi.org/10.1016/j.neuroscience.2006.11.055
https://doi.org/10.1016/j.neuroscience.2006.11.055