Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Jean Celli"'
Autor:
Erin P. Smith, Alexis Cotto-Rosario, Elizabeth Borghesan, Kiara Held, Cheryl N. Miller, Jean Celli
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Intracellular bacterial pathogens remodel cellular functions during their infectious cycle via the coordinated actions of effector molecules delivered through dedicated secretion systems. While the function of many individual effectors is kn
Externí odkaz:
https://doaj.org/article/f7dfe2eccd2248279ea9482b3b7e79ea
Autor:
Mariana X. Byndloss, April Y. Tsai, Gregory T. Walker, Cheryl N. Miller, Briana M. Young, Bevin C. English, Núbia Seyffert, Tobias Kerrinnes, Maarten F. de Jong, Vidya L. Atluri, Maria G. Winter, Jean Celli, Renée M. Tsolis
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT Subversion of endoplasmic reticulum (ER) function is a feature shared by multiple intracellular bacteria and viruses, and in many cases this disruption of cellular function activates pathways of the unfolded protein response (UPR). In the ca
Externí odkaz:
https://doaj.org/article/8f930186dae34fdd85cfc411dd999958
Autor:
Nicole Lau, Amanda L Haeberle, Brittany J O'Keeffe, Eleanor A Latomanski, Jean Celli, Hayley J Newton, Leigh A Knodler
Publikováno v:
PLoS Pathogens, Vol 15, Iss 7, p e1007959 (2019)
The enteric bacterial pathogen Salmonella enterica serovar Typhimurium (S. Typhimurium), utilizes two type III secretion systems (T3SSs) to invade host cells, survive and replicate intracellularly. T3SS1 and its dedicated effector proteins are requir
Externí odkaz:
https://doaj.org/article/3a7d4c4d4d01451db86a16ce68ffaa89
Publikováno v:
mBio, Vol 7, Iss 6 (2016)
ABSTRACT Brucella abortus, the bacterial agent of the worldwide zoonosis brucellosis, primarily infects host phagocytes, where it undergoes an intracellular cycle within a dedicated membrane-bound vacuole, the Brucella-containing vacuole (BCV). Initi
Externí odkaz:
https://doaj.org/article/42b8300053ea47208c46580f0162ca5f
Autor:
Maarten F. de Jong, Tregei Starr, Maria G. Winter, Andreas B. den Hartigh, Robert Child, Leigh A. Knodler, Jan Maarten van Dijl, Jean Celli, Renée M. Tsolis
Publikováno v:
mBio, Vol 4, Iss 1 (2013)
ABSTRACT Host cytokine responses to Brucella abortus infection are elicited predominantly by the deployment of a type IV secretion system (T4SS). However, the mechanism by which the T4SS elicits inflammation remains unknown. Here we show that translo
Externí odkaz:
https://doaj.org/article/708e716606f1474fb06f4ac852025a7a
Autor:
Audrey Chong, Robert Child, Tara D Wehrly, Dedeke Rockx-Brouwer, Aiping Qin, Barbara J Mann, Jean Celli
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67965 (2013)
Francisella tularensis is a highly infectious bacterium whose virulence relies on its ability to rapidly reach the macrophage cytosol and extensively replicate in this compartment. We previously identified a novel Francisella virulence factor, DipA (
Externí odkaz:
https://doaj.org/article/5cab4600db4a4ef19ec4c01080f2108b
Autor:
Sebenzile Myeni, Robert Child, Tony W Ng, John J Kupko, Tara D Wehrly, Stephen F Porcella, Leigh A Knodler, Jean Celli
Publikováno v:
PLoS Pathogens, Vol 9, Iss 8, p e1003556 (2013)
The intracellular pathogenic bacterium Brucella generates a replicative vacuole (rBCV) derived from the endoplasmic reticulum via subversion of the host cell secretory pathway. rBCV biogenesis requires the expression of the Type IV secretion system (
Externí odkaz:
https://doaj.org/article/34971f7e393b47f89c27fac22e30ea47
Autor:
Dedeke Rockx-Brouwer, Audrey Chong, Tara D Wehrly, Robert Child, Deborah D Crane, Jean Celli, Catharine M Bosio
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37752 (2012)
Tularemia, caused by the gram-negative bacterium Francisella tularensis, is a severe, sometimes fatal disease. Interest in tularemia has increased over the last decade due to its history as a biological weapon. In particular, development of novel vac
Externí odkaz:
https://doaj.org/article/354bf3ef51e0422b8362ef4ce631232c
Publikováno v:
PLoS Pathogens, Vol 5, Iss 1, p e1000278 (2009)
Legionella pneumophila is an opportunistic pathogen that can cause a severe pneumonia called Legionnaires' disease. In the environment, L. pneumophila is found in fresh water reservoirs in a large spectrum of environmental conditions, where the bacte
Externí odkaz:
https://doaj.org/article/03cc011a33714e2e81ad51733a82c304
Publikováno v:
Infection and Immunity. 91
Brucella abortus , the intracellular causative agent of brucellosis, relies on type IV secretion system (T4SS) effector-mediated modulation of host cell functions to establish a replicative niche, the Brucella -containing vacuole (BCV). Brucella expl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae5833000d742f18bf082c5e732e2287
https://doi.org/10.1128/iai.00130-23
https://doi.org/10.1128/iai.00130-23