Zobrazeno 1 - 10
of 172
pro vyhledávání: '"Jean C Shih"'
Autor:
David A Davis, Marco Bortolato, Sean C Godar, Thomas K Sander, Nahoko Iwata, Payam Pakbin, Jean C Shih, Kiros Berhane, Rob McConnell, Constantinos Sioutas, Caleb E Finch, Todd E Morgan
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64128 (2013)
Emerging evidence suggests that excessive exposure to traffic-derived air pollution during pregnancy may increase the vulnerability to neurodevelopmental alterations that underlie a broad array of neuropsychiatric disorders. We present a mouse model
Externí odkaz:
https://doaj.org/article/24a58c963b1b498eb1dd3176e09a7de1
Autor:
Priya Jayachandran, Francesca Battaglin, Carly Strelez, Annika Lenz, Sandra Algaze, Shivani Soni, Jae Ho Lo, Yan Yang, Joshua Millstein, Wu Zhang, Jean C. Shih, Janice Lu, Shannon M. Mumenthaler, Darcy Spicer, Josh Neman, Evanthia T. Roussos Torres, Heinz-Josef Lenz
Publikováno v:
Oncogene. 42:627-637
Exploring the relationship between various neurotransmitters and breast cancer cell growth has revealed their likely centrality to improving breast cancer treatment. Neurotransmitters play a key role in breast cancer biology through their effects on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8be946c3a46f7fb9c26c3f4e1a24493
https://doi.org/10.1038/s41388-022-02584-4
https://doi.org/10.1038/s41388-022-02584-4
Autor:
Francesca Battaglin, Priya Jayachandran, Carly Strelez, Annika Lenz, Sandra Algaze, Shivani Soni, Jae Ho Lo, Yan Yang, Joshua Millstein, Wu Zhang, Evanthia T. Roussos Torres, Jean C. Shih, Shannon M. Mumenthaler, Josh Neman, Heinz-Josef Lenz
Publikováno v:
Oncogene. 41:4769-4778
The brain-gut axis, a bidirectional network between the central and enteric nervous system, plays a critical role in modulating the gastrointestinal tract function and homeostasis. Recently, increasing evidence suggests that neuronal signaling molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17c622be0816f9b388719d8f8f56adbc
https://doi.org/10.1038/s41388-022-02479-4
https://doi.org/10.1038/s41388-022-02479-4
Publikováno v:
Brain Sciences, Vol 11, Iss 10, p 1318 (2021)
Our previous work has shown that monoamine oxidase A (MAO A) is overexpressed in glioma and prostate cancer. Near-infrared dye conjugate MAO A Inhibitor (NMI) inhibited the growth of these cancers. This study investigated the effects of NMI on other
Externí odkaz:
https://doaj.org/article/82b38678d0d24beb91dbdc0aab39061b
Autor:
Jean C. Shih, Boyang Jason Wu, Leland W.K. Chung, Haiyen E. Zhau, Chi-Hung Lin, Gina Chia-Yi Chu, Jen-Ming Huang, Ni Zeng, Chunyan Liu, Xiangyan Li, Qinlong Li, Jingjing Li, Tzu-Ping Lin
Figure S1: R1 does not affect contact inhibition during prostate cancer cell proliferation; Figure S2: R1 does not affect cell apoptosis in prostate cancer cells under both steady state and dynamic conditions; Figure S3: R1 promotes prostate cancer c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e50375be7b4a8667cadc65f4e54a1c6b
https://doi.org/10.1158/1541-7786.22511707
https://doi.org/10.1158/1541-7786.22511707
Publikováno v:
Journal of Medicinal Chemistry. 65:2208-2224
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc54064a4af46c69e7d3c7bbb30efe60
https://doi.org/10.1021/acs.jmedchem.1c01726
https://doi.org/10.1021/acs.jmedchem.1c01726
Autor:
Boyang Jason Wu, Jean C. Shih
Publikováno v:
Methods Mol Biol
Methods in Molecular Biology ISBN: 9781071626429
Methods in Molecular Biology ISBN: 9781071626429
Emerging studies, including ours, have revealed the novel essential roles of monoamine oxidase A (MAO A) in mediating the growth and progression of several types of cancers. Recently, we presented the first evidence of MAO A’s ability to promote ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206ef3e09b80a009dc63dcc0b33599c8
https://europepmc.org/articles/PMC9651040/
https://europepmc.org/articles/PMC9651040/
Autor:
Qian Shi, Hamza Malik, Jennifer Streeter, Jinxi Wang, Ran Huo, Rachel M. Crawford, Jean C. Shih, Biyi Chen, Duane Hall, E. Dale Abel, Long-Sheng Song, Ethan J. Anderson
BackgroundPeople with clinical depression exhibit increased risk for cardiac arrhythmias that could be related to differences in catecholamine metabolism. Emerging studies have implicated a pathophysiologic role for monoamine oxidase (MAO-A), which c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f0e5284705c819a3bb777143b7a45ab
https://doi.org/10.1101/2022.09.29.510139
https://doi.org/10.1101/2022.09.29.510139
Autor:
Jessica A. Lapierre, Lauren A. Geary, Julie K. Jang, Alan L. Epstein, Frank Hong, Jean C. Shih
Publikováno v:
Biochemical and biophysical research communications. 634
We have previously shown that monoamine oxidase A (MAO A) mediates prostate cancer growth and metastasis. Further, MAO A/Pten double knockout (DKO) mice were generated and demonstrated that the deletion of MAO A delayed prostate tumor development in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc1f8a232362abea240241b46bf8d723
https://pubmed.ncbi.nlm.nih.gov/36242915
https://pubmed.ncbi.nlm.nih.gov/36242915
Publikováno v:
Brain, behavior, and immunity. 107
Monoamine oxidase A (MAO A) is the critical enzyme to degrade serotonin in the brain and the knockout mouse exhibits hyperserotonemia and abnormalities that are observed in autism spectrum disorder (ASD). Thus, the MAO A knockout mouse is a valuable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5466c64371d8b34aa8a0f2a46bb62265
https://pubmed.ncbi.nlm.nih.gov/36243286
https://pubmed.ncbi.nlm.nih.gov/36243286