Lexical-perceptual integration influences sensorimotor adaptation in speech

Autor: Nicolas Jean Bourguignon, Shari R. Baum, Douglas M Shiller

Publikováno v: Frontiers in Human Neuroscience, Vol 8 (2014)

A combination of lexical bias and altered auditory feedback was used to investigate the influence of higher-order linguistic knowledge on the perceptual aspects of speech motor control. Subjects produced monosyllabic real words or pseudo-words contai

Externí odkaz: https://doaj.org/article/fc36804e76b74929a26c5302f7d9265a

Allosteric Functional Switch of Neurokinin A-Mediated Signaling at the Neurokinin NK2 Receptor: Structural Exploration

Autor: Jean Bourguignon, Celine Valant, Bernard Bucher, Jean Luc Galzi, Marcel Hibert, Valérie Utard, Emeline Maillet

Publikováno v: Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2009, 52 (19), pp.5999-6011. ⟨10.1021/jm900671k⟩

International audience; The neurokinin NK2 receptor is known to pre-exist in equilibrium between at least three states: resting-inactive, calcium-triggering, and cAMP-producing. Its endogeneous ligand, NKA, mainly induces the calcium response. Using

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a7ea47843416908d168833a5d75643
https://doi.org/10.1021/jm900671k

Chiral biomimetic NADH models in the benzo[b]-1,6-naphthyridine series. A novel class of stable, reactive and highly enantioselective NADH mimics

Autor: Jean-Luc Vasse, Vincent Levacher, Georges Dupas, Jean Bourguignon

Publikováno v: Tetrahedron. 59:4911-4921

The preparation of a new class of tricyclic models 1 based on a Friedlander reaction between chiral piperidine-2,4-diones 2 and azomethine 3 is reported. Alkylation of the lactam allowed to install various pendant arms on the chiral cyclic inducer. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::800750fbb48581b357835aa39e87380f
https://doi.org/10.1016/s0040-4020(03)00706-3

Design of new axially chiral NADH mimics. Mechanistic investigation of the enantioselective hydride transfer

Autor: J. Duflos, Jean-Luc Vasse, Georges Dupas, Jean Bourguignon, Vincent Levacher, Guy Quéguiner

Publikováno v: Tetrahedron Letters. 42:4613-4616

This paper reports the design of a new axially chiral NADH model which relies on the configurational control around the C3-CO chiral axis by means of a chiral relay installed on the cyclic structure. The conformational and configurational control

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ab1b343a2112809116d72aae7517adbd
https://doi.org/10.1016/s0040-4039(01)00805-x

A convenient synthesis of 3,4-difunctionalized δ-carbolines

Autor: Jean Bourguignon, Cyril Papamicaël, Guy Quéguiner, Georges Dupas

Publikováno v: Tetrahedron. 57:5385-5391

An efficient and direct preparation of functionalized δ-carbolines, via a ring closure reaction between the appropriate indole amine and a masked 1,3-dicarbonyl compound is described. This method afforded new 3-substituted δ-carbolines and these pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eda646680fc8d187e7902757b0131715
https://doi.org/10.1016/s0040-4020(01)00435-5