Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Jean Bernard Lubin"'
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Weaning, the transition from a milk-based diet to solid food, coincides with the most significant shift in gut microbiome composition in the lifetime of most mammals. Notably, this period also marks a “window of opportunity” where key components
Externí odkaz:
https://doaj.org/article/a4c187ad4d7d48d8b9f253d27cd84ce8
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
The intestinal microbiome during infancy and childhood has distinct metabolic functions and microbial composition compared to adults. We recently published a gnotobiotic mouse model of the pre-weaning microbiome (PedsCom), which retains a pre-weaning
Externí odkaz:
https://doaj.org/article/b0264bbb6db1470597cb619ad00fc3f9
Autor:
Peyton E. Conrey, Lidiya Denu, Kaitlin C. O’Boyle, Isaiah Rozich, Jamal Green, Jeffrey Maslanka, Jean-Bernard Lubin, Tereza Duranova, Brittany L. Haltzman, Lauren Gianchetti, Derek A. Oldridge, Nina De Luna, Laura A. Vella, David Allman, Jonathan M. Spergel, Ceylan Tanes, Kyle Bittinger, Sarah E. Henrickson, Michael A. Silverman
Publikováno v:
Science Immunology. 8
The ability of most patients with selective immunoglobulin A (IgA) deficiency (SIgAD) to remain apparently healthy has been a persistent clinical conundrum. Compensatory mechanisms, including IgM, have been proposed, yet it remains unclear how secret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1a5e902e05987d3033059e4880acc89
https://doi.org/10.1126/sciimmunol.ade2335
https://doi.org/10.1126/sciimmunol.ade2335
Arresting microbiome development limits immune system maturation and resistance to infection in mice
Autor:
Jean-Bernard Lubin, Jamal Green, Sarah Maddux, Lidiya Denu, Tereza Duranova, Matthew Lanza, Meghan Wynosky-Dolfi, Julia N. Flores, Logan P. Grimes, Igor E. Brodsky, Paul J. Planet, Michael A. Silverman
Publikováno v:
Cell Host & Microbe. 31:554-570.e7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8387173aa107dd23dac8a2da4624b50c
https://doi.org/10.1016/j.chom.2023.03.006
https://doi.org/10.1016/j.chom.2023.03.006
Publikováno v:
mBio, Vol 7, Iss 2 (2016)
ABSTRACT A major challenge facing bacterial intestinal pathogens is competition for nutrient sources with the host microbiota. Vibrio cholerae is an intestinal pathogen that causes cholera, which affects millions each year; however, our knowledge of
Externí odkaz:
https://doaj.org/article/645db41820df4967b4e93162237d5101
Autor:
Jean-Bernard Lubin, Jamal Green, Sarah Maddux, Lidiya Denu, Tereza Duranova, Matthew Lanza, Meghan Wynosky-Dolfi, Igor E. Brodsky, Paul J. Planet, Michael A. Silverman
Disruptions to the intestinal microbiome during weaning lead to long-term negative effects on host immune function. However, the critical host-microbe interactions occurring during weaning required for healthy immune system development remain poorly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8348780b5eb12ac8dc85601f9655e381
https://doi.org/10.1101/2022.01.17.476513
https://doi.org/10.1101/2022.01.17.476513
Autor:
Sarah E. Henrickson, Ceylan Tanes, Lauren Gianchetti, David Allman, Lidiya Denu, Michael A. Silverman, Kaitlin C. O’Boyle, Jonathan M. Spergel, Derek A. Oldridge, Peyton Conrey, Jean-Bernard Lubin, Jamal Green, Brittany L. Haltzman, Jeffrey Maslanka, Laura A. Vella, Kyle Bittinger, Tereza Duranova
SummaryMammals produce large quantities of mucosal and systemic antibodies that maintain the intestinal barrier, shape the intestinal microbiome and promote lifelong mutualism with commensal microbes. Here, we developed an integrated host-commensal a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f25a30ca4d9c2c7c36615139265b084f
https://doi.org/10.1101/2021.08.20.21261620
https://doi.org/10.1101/2021.08.20.21261620
Autor:
Michael A Silverman, Jean-Bernard Lubin, Lidiya Denu, Jamal Green, Tereza Duranova, Mathew Lanza, Meghan Wynosky-Dolfi, Igor E. Brodsky, Paul Planet
Publikováno v:
The Journal of Immunology. 208:59.01-59.01
The transition from milk to solid food is a critical period in post-natal human development. Weaning coincides with a dramatic and rapid maturation of both the microbiome and immune system. Whether these weaning induced changes in commensal communiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbce5ff1916ecd4ab60b63a092368489
https://doi.org/10.4049/jimmunol.208.supp.59.01
https://doi.org/10.4049/jimmunol.208.supp.59.01
Autor:
Michael A Silverman, Peyton E. Conrey, Lidiya Denu, Kaitlin C O’Boyle, Ceylan Tanes, Jamal Green, Kyle Bittinger, David Allman, Jean-Bernard Lubin, Tereza Duranova, Derek Oldridge, Sarah Henrickson
Publikováno v:
The Journal of Immunology. 208:160.06-160.06
Mammals produce large quantities of mucosal and systemic antibodies that maintain the intestinal barrier, shape the intestinal microbiome and promote lifelong mutualism with commensal microbes. Here, we developed an integrated host-commensal approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d15a3fdf22dd89eda318a493520ffeb
https://doi.org/10.4049/jimmunol.208.supp.160.06
https://doi.org/10.4049/jimmunol.208.supp.160.06