Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Jean Baptiste Charbonnier"'
Autor:
Akbar Zainu, Pauline Dupaigne, Soumya Bouchouika, Julien Cau, Julie A. J. Clément, Pauline Auffret, Virginie Ropars, Jean-Baptiste Charbonnier, Bernard de Massy, Raphael Mercier, Rajeev Kumar, Frédéric Baudat
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract During meiosis, nucleoprotein filaments of the strand exchange proteins RAD51 and DMC1 are crucial for repairing SPO11-generated DNA double-strand breaks (DSBs) by homologous recombination (HR). A balanced activity of positive and negative R
Externí odkaz:
https://doaj.org/article/b23ba1e45f564ac9871d10aea2621def
Autor:
Giordano Reginato, Maria Rosaria Dello Stritto, Yanbo Wang, Jingzhou Hao, Raphael Pavani, Michael Schmitz, Swagata Halder, Vincent Morin, Elda Cannavo, Ilaria Ceppi, Stefan Braunshier, Ananya Acharya, Virginie Ropars, Jean-Baptiste Charbonnier, Martin Jinek, Andrè Nussenzweig, Taekjip Ha, Petr Cejka
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract The outcome of CRISPR-Cas-mediated genome modifications is dependent on DNA double-strand break (DSB) processing and repair pathway choice. Homology-directed repair (HDR) of protein-blocked DSBs requires DNA end resection that is initiated b
Externí odkaz:
https://doaj.org/article/9468f29a4c104f0db450028e4975e766
Autor:
Julien Bischerour, Olivier Arnaiz, Coralie Zangarelli, Vinciane Régnier, Florence Iehl, Virginie Ropars, Jean-Baptiste Charbonnier, Mireille Bétermier
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114001- (2024)
Summary: In the ciliate Paramecium, precise excision of numerous internal eliminated sequences (IESs) from the somatic genome is essential at each sexual cycle. DNA double-strands breaks (DSBs) introduced by the PiggyMac endonuclease are repaired in
Externí odkaz:
https://doaj.org/article/c96205092865484984ef481158bee425
Autor:
Florian Roisné-Hamelin, Sabrina Pobiega, Kévin Jézéquel, Simona Miron, Jordane Dépagne, Xavier Veaute, Didier Busso, Marie-Hélène Le Du, Isabelle Callebaut, Jean-Baptiste Charbonnier, Philippe Cuniasse, Sophie Zinn-Justin, Stéphane Marcand
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Different proteins localised at telomeres ensure chromosome end stability to prevent double strand-end break recognition. Here the authors provide new insight into how in S. cerevisiae the interaction between Rif2 and Rad50 inhibits MRX functions at
Externí odkaz:
https://doaj.org/article/26d231c1f074477282f58ddee8bde50e
Autor:
Benoit Roch, Vincent Abramowski, Olivier Etienne, Stefania Musilli, Pierre David, Jean-Baptiste Charbonnier, Isabelle Callebaut, François D Boussin, Jean-Pierre de Villartay
Publikováno v:
eLife, Vol 10 (2021)
We developed an Xrcc4M61R separation of function mouse line to overcome the embryonic lethality of Xrcc4-deficient mice. XRCC4M61R protein does not interact with Xlf, thus obliterating XRCC4-Xlf filament formation while preserving the ability to stab
Externí odkaz:
https://doaj.org/article/9f2b7f8042e7416dbee800b5e8f5606b
Autor:
Prashant P. Damke, Anne Marie Di Guilmi, Paloma Fernández Varela, Christophe Velours, Stéphanie Marsin, Xavier Veaute, Mérick Machouri, Gaurav V. Gunjal, Desirazu N. Rao, Jean-Baptiste Charbonnier, J. Pablo Radicella
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Some bacteria can take up DNA molecules from the environment. Here, Damke et al. identify a DNA-binding protein in Helicobacter pylori that is required for DNA import into the periplasm and that interacts with an inner-membrane channel that transloca
Externí odkaz:
https://doaj.org/article/d6cc5dff533e482ebd0d89385013b9ec
Autor:
Akbar Zainu, Pauline Dupaigne, Soumya Bouchouika, Julien Cau, Julie A. J. Clément, Pauline Auffret, Virginie Ropars, Jean-Baptiste Charbonnier, Bernard de Massy, Rajeev Kumar, Frédéric Baudat
During meiosis, nucleoprotein filaments of the strand exchange proteins RAD51 and DMC1 are crucial for repairing SPO11-generated DNA double-strand breaks (DSBs) by homologous recombination (HR). A balanced activity of positive and negative RAD51/DMC1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93ab84a7b016f89a60e516b68837e102
https://doi.org/10.1101/2023.05.17.541096
https://doi.org/10.1101/2023.05.17.541096
Autor:
Satish K. Tadi, Carine Tellier-Lebègue, Clément Nemoz, Pascal Drevet, Stéphane Audebert, Sunetra Roy, Katheryn Meek, Jean-Baptiste Charbonnier, Mauro Modesti
Publikováno v:
Cell Reports, Vol 17, Iss 2, Pp 541-555 (2016)
In mammalian cells, classical non-homologous end joining (c-NHEJ) is critical for DNA double-strand break repair induced by ionizing radiation and during V(D)J recombination in developing B and T lymphocytes. Recently, PAXX was identified as a c-NHEJ
Externí odkaz:
https://doaj.org/article/c861e7cc7c714c09a07a270f4bfd07e7
Autor:
Carine Tellier-Lebegue, Eléa Dizet, Emilie Ma, Xavier Veaute, Eric Coïc, Jean-Baptiste Charbonnier, Laurent Maloisel
Publikováno v:
PLoS Genetics, Vol 14, Iss 2, p e1007236 (2018)
[This corrects the article DOI: 10.1371/journal.pgen.1007119.].
Externí odkaz:
https://doaj.org/article/ba4343d950c641c28f528ae2004ba97d
Autor:
Carine Tellier-Lebegue, Eléa Dizet, Emilie Ma, Xavier Veaute, Eric Coïc, Jean-Baptiste Charbonnier, Laurent Maloisel
Publikováno v:
PLoS Genetics, Vol 13, Iss 12, p e1007119 (2017)
Replicative DNA polymerases cannot insert efficiently nucleotides at sites of base lesions. This function is taken over by specialized translesion DNA synthesis (TLS) polymerases to allow DNA replication completion in the presence of DNA damage. In e
Externí odkaz:
https://doaj.org/article/ffa8c3b1930d4be392ff350a6aaa94ce