Zobrazeno 1 - 10
of 512
pro vyhledávání: '"Jean Krutmann"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Human induced pluripotent stem cells (iPSCs) have great potential in research, but pluripotency testing faces challenges due to non-standardized methods and ambiguous markers. Here, we use long-read nanopore transcriptome sequencing to disco
Externí odkaz:
https://doaj.org/article/e144b945c29e44ca871a16b9e9f95679
Autor:
Ana C. B. Sant'Anna‐Silva, Thomas Botton, Andrea Rossi, Jochen Dobner, Hanene Bzioueche, Nguyen Thach, Lauriane Blot, Sophie Pagnotta, Konrad Kleszczynski, Kerstin Steinbrink, Nathalie M. Mazure, Stéphane Rocchi, Jean Krutmann, Thierry Passeron, Meri K. Tulic
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 8, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/9305f8c0f89f41ec8074cb830bcb975d
Autor:
Henry William Lim, Thierry Passeron, Chee Leok Goh, Hee Young Kang, Fatimata Ly, Akimichi Morita, Jorge Ocampo-Candiani, Susana Puig, Sergio Schalka, Liu Wei, Anne Laure Demessant, Caroline Le Floc'h, Delphine Kerob, Brigitte Dreno, Jean Krutmann
Publikováno v:
Acta Dermato-Venereologica, Vol 104 (2024)
Secondary prevention of skin cancer consists in early detection of malignant lesions through patients’ mole self-examination and medical examination. The objective of this study was to assess the self-reported frequency of mole examination in a lar
Externí odkaz:
https://doaj.org/article/829775cbb5d04e6fbaf83563bea6abbd
Autor:
Jochen Dobner, Thach Nguyen, Mario Gustavo Pavez-Giani, Lukas Cyganek, Felix Distelmaier, Jean Krutmann, Alessandro Prigione, Andrea Rossi
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 2, Pp 101231- (2024)
Mitochondrial DNA (mtDNA) analysis is crucial for the diagnosis of mitochondrial disorders, forensic investigations, and basic research. Existing pipelines are complex, expensive, and require specialized personnel. In many cases, including the diagno
Externí odkaz:
https://doaj.org/article/d31d09eb2eb54ccb8689a2489ed1f56a
Autor:
Leon-Phillip Szepanowski, Wasco Wruck, Julia Kapr, Andrea Rossi, Ellen Fritsche, Jean Krutmann, James Adjaye
Publikováno v:
Cells, Vol 13, Iss 7, p 591 (2024)
Cockayne syndrome (CS) is a rare hereditary autosomal recessive disorder primarily caused by mutations in Cockayne syndrome protein A (CSA) or B (CSB). While many of the functions of CSB have been at least partially elucidated, little is known about
Externí odkaz:
https://doaj.org/article/70e7179b5ce543bb92c75c6417032f50
Autor:
Torben Stermann, Thach Nguyen, Burkhard Stahlmecke, Ana Maria Todea, Selina Woeste, Inken Hacheney, Jean Krutmann, Klaus Unfried, Roel P. F. Schins, Andrea Rossi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Cystic fibrosis is an autosomal recessive disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) that can lead to terminal respiratory failure. Ultrafine carbonaceous particles, which are ubiquitous in
Externí odkaz:
https://doaj.org/article/d7c64df7cb9a4ae78e391e5e35ce98aa
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 253, Iss , Pp 114676- (2023)
Previous studies have found associations between chromium exposure and skin damage. However, few studies have focused on both chromium and skin aging. This study aimed to assess the degree of skin aging symptoms and estimate the relationship between
Externí odkaz:
https://doaj.org/article/d5837e5f17254dee923dc2355b91c13c
Autor:
Carr Cai, Bill Zeng, Lydia Lin, Miranda Zheng, Carolina Burki, Susanne Grether‐Beck, Jean Krutmann
Publikováno v:
Health Science Reports, Vol 6, Iss 1, Pp n/a-n/a (2023)
Abstract Background and Aims Female pattern hair loss affects females of all ages with a trend to increase after menopause. This disorder may have significant psychological impact and lead to anxiety and depression. Objective In a single center, doub
Externí odkaz:
https://doaj.org/article/d4b34f26578f4f2fba8c2730b9227306
Autor:
Christian Vogeley, Thach Nguyen, Selina Woeste, Jean Krutmann, Thomas Haarmann-Stemmann, Andrea Rossi
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Transcriptome analysis experiments enable researchers to gain extensive insights into the molecular mechanisms underlying cell physiology and disease. Oxford Nanopore Technologies (ONT) has recently been developed as a fast, miniaturized, portable, a
Externí odkaz:
https://doaj.org/article/1dc9924d50894a9798481771054e0b0c
Autor:
Timothy Budden, Caroline Gaudy-Marqueste, Andrew Porter, Emily Kay, Shilpa Gurung, Charles H. Earnshaw, Katharina Roeck, Sarah Craig, Víctor Traves, Jean Krutmann, Patricia Muller, Luisa Motta, Sara Zanivan, Angeliki Malliri, Simon J. Furney, Eduardo Nagore, Amaya Virós
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Ultraviolet radiation (UVR) increases melanoma incidence. Here, the authors report that UVR-damaged dermal fibroblasts upregulate MMP1 to degrade collagen which inhibits melanoma invasion and that aged primary melanomas in skin with degraded collagen
Externí odkaz:
https://doaj.org/article/f3eebf3f892a42e28f17cc0ebdce6bf8